Potent Suppression of Kv1.3 Potassium Channel and IL-2 Secretion by Diphenyl Phosphine Oxide-1 in Human T Cells by Ning Zhao (84707)

“…<div><p>Diphenyl phosphine oxide-1 (DPO-1) is a potent Kv1.5 channel inhibitor that has therapeutic potential for the treatment of atrial fibrillation. …”

Disease progression phenotypes, clinical cohorts, and our computational framework together with the reproducibility of disease progression pattern. by Kimiyo N. Yamamoto (213724)

The experimentally reported network parameters can generate supersaturation and be adapted to enter the inhibition-stabilized state. by Pierre Ekelmans (15470955)

“…This results in a decrease in the firing rates of both populations, as predicted by the SSN (dashed lines). …”

Leaf extracts of Campomanesia xanthocarpa positively regulates atherosclerotic-related protein expression by EDUARDO B.B. CUNHA (10363794)

“…Cell viability was affected only at higher concentrations and times. We observed decreased ICAM-1 expression in cells treated with 50 μg/ml EG and CD14 expression with IFN-γ and without IFN-γ. …”

Deletion of diploid-specific doxorubicin resistance genes result in cell cycle progression or recombination defects. by Tammy J. Westmoreland (38006)

“…Single unbudded (G1) cells were arrayed into 5×4 cell grids on YPD with and without doxorubicin (50 µg/ml). …”

Results of MRE measurements and histological cell counts in the substantia nigra. by Elisabeth G. Hain (542261)

“…<p>MPTP induced a significant reduction in MRE elasticity (a) and viscosity (b) in the substantia nigra (mean±SEM, n(-3,3,6,10,14,18dpi) = 5). DAB-stained brain sections showed an immediate significant drop in TH+ dopaminergic neurons in the substantia nigra after MPTP treatment (c) (mean±SEM, n(-3dpi) = 4, n(3,6,10,14,18dpi) = 5). …”

Factors that drive zooplankton diversity in Neo-Tropical Savannah shallow lakes by Claudia Padovesi-Fonseca (4653880)

Myotonia-causing mutations and the putative binding pocket of the 9-AC inhibitor. by Kaituo Wang (6193994)

“…(a) Overall view with all known disease and selected experimental mutations. We note that mutations of 5 residues that cause recessive myotonia and inward rectification are facing the extracellular vestibule; 3 located in a row on the same face of on helix B (M128, S132, D136) and 2 being the pore-constricting residues (K231, R421). …”

The effect of stimulus luminance on pupil dilation. by Elena Geangu (339260)

“…Illuminance measured at the level of the eye during the presentation of each video was within a range not expected to yield significant differences in pupil size (15.0±0.5 Lux) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027132#pone.0027132-MacLachlan1" target="_blank">[50]</a>. …”

HSV-2-specific CD4⁺ and CD8⁺ T cell responses are detected in HSV-2/SHIV-RT co-infected animals. by Federica Crostarosa (256646)

“…(D) Approximately 12 months after challenge with SHIV-RT or co-challenge with HSV-2/SHIV-RT, the fold decreases in CD4 counts (mean±SEM, relative to pre-exposure levels) (left axis, stars) and plasma viral loads (mean RNA copies/ml±SEM, right axis, circles) are shown (n = 5 for both).…”

<b>Single-dose replicon RNA Sudan virus vaccine uniformly protects female guinea pigs from disease</b> by Andrea Marzi (758337)

“…We demonstrate 100% survival and protection with the LION-SUDV and the LION-Combination vaccines, while the LION-EBOV vaccine achieved 50% protection. Antigen-specific humoral responses correlate with decreased virus replication and survival. …”

Table_1_Evaluation of a machine learning algorithms for predicting the dental age of adolescent based on different preprocessing methods.docx by Shihui Shen (7208720)

“…</p>Subjects and methods<p>We analyzed 748 orthopantomographs (392 males and 356 females) from eastern China between the age of 5 and 13 years in this retrospective study. …”

Regulation of targets by EWS in vivo. by Sujitha Duggimpudi (699551)

“…Pie diagram showing the distribution of PAR-CLIP clusters across 3’UTR, 5’UTR, intronic and coding regions of Refseq RNAs. …”

Table_1_Arterial oxygenation and acid–base status before and during oxygen supplementation in captive European bison (Bison bonasus) immobilized with etorphine-acepromazine-xylazin... by Nino Gardoni (16316643)

“…We observed decreased respiratory rates and pH and mild hypercapnia consistent with a mild respiratory acidosis. …”

Table_2_Arterial oxygenation and acid–base status before and during oxygen supplementation in captive European bison (Bison bonasus) immobilized with etorphine-acepromazine-xylazin... by Nino Gardoni (16316643)

“…We observed decreased respiratory rates and pH and mild hypercapnia consistent with a mild respiratory acidosis. …”

<i>In vivo</i> mitochondrial metabolism in SOD1^−/− mice. by Michael P. Siegel (195229)

“…Data are expressed as means ± SEM with n = 4–5 per group. In C, data are normalized to control averages. …”

Early and Late-Term Follow-Up Results of Patients Diagnosed with Aortic Aneurysm or Aortic Dissection with Aortic Regurgitation Undergoing Aortic Valve Repair or Valve-Sparing Aort... by Görkem Yiğit (10392838)

“…Freedom from reoperation in one, two, and five years were 97.9%, 93.6%, and 81%, respectively. …”

Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting by Geoffrey P. Chase (207164)

“…To characterize the composition of vRNP export complexes and their interplay with the nucleus of infected cells, we affinity-purified tagged vRNPs from biochemically fractionated infected nuclei. …”

Deletion of <i>Foxm1</i> from macrophages induces activation of p38 MAPK pathway. by Chinmayee Goda (8694597)

“…<p><b>(A-B)</b> Interstitial and alveolar macrophages were isolated from bleomycin-treated my<i>Foxm1</i>^-/- and control lungs using FACS sorting. qRT-PCR shows decreased <i>Foxm1</i>, and <i>Dusp1</i> mRNAs and increased <i>Tnf</i>, <i>Ccl5</i>, <i>Il1β</i>, and <i>Il6</i> mRNAs in flow-sorted interstitial and alveolar macrophages from bleomycin-treated my<i>Foxm1</i>^-/- mice. …”

TF maps and averaged profile of alpha oscillatory response. by Audrey Breton (534422)

“…<p>A) TF map depicting the color-coded mean energy (in μV²) in response to faces in the three player rank conditions (Highest, Middle and Lowest) at the electrode Pz. …”