DataSheet2_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Supp... by Fei-lin Ge (11611192)

“…The inhibition rates of LWWL (0.8 mg/ml) on HBV DNA, HBsAg, and pgRNA were 57.06, 38.55, and 62.49% in HepG2.2.15 cells, and 51.57, 17.57, and 53.88% in HepG2. A64 cells, respectively. LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”

DataSheet7_Chinese Patent Medicine Liuweiwuling Tablet had Potent Inhibitory Effects on Both Wild-Type and Entecavir-Resistant Hepatitis B Virus (HBV) in vitro and Effectively Supp... by Fei-lin Ge (11611192)

“…The inhibition rates of LWWL (0.8 mg/ml) on HBV DNA, HBsAg, and pgRNA were 57.06, 38.55, and 62.49% in HepG2.2.15 cells, and 51.57, 17.57, and 53.88% in HepG2. A64 cells, respectively. LWWL (2 g kg⁻¹ d⁻¹ for 4 weeks)-treated mice had 1.16 log₁₀ IU/mL decrease of serum HBV DNA, and more than 50% decrease of serum HBsAg/HBeAg and hepatic HBsAg/HBcAg. …”

Atherosclerosis development is reduced with virgin pumpkin seed oil. by Martine C. Morrison (800552)

“…E: Immunohistochemical staining for MAC-3 (CD107b) followed by quantification of positively stained area showed that both REF and VIR reduced the macrophage content of type V lesions. Data are mean±SEM. * p≤0.05, ** p≤0.01 compared with CON.…”

Table_1_Relevance of PUFA-derived metabolites in seminal plasma to male infertility.xlsx by Xiangfeng Chen (1548517)

“…In men with normozoospermia, higher levels of 7(R)-MaR1 (HR: 0.4 (95% CI [0.24, 0.64]) and 11,12-DHET (0.36 (95% CI [0.21, 0.58]) were significantly associated with a decreased risk of infertility, while higher levels of 17(S)-HDHA (HR: 2.32 (95% CI [1.44, 3.79]), LXA5 (HR: 8.38 (95% CI [4.81, 15.24]), 15d-PGJ2 (HR: 1.71 (95% CI [1.06, 2.76]), and PGJ2 (HR: 2.28 (95% CI [1.42, 3.7]) correlated with an increased risk of infertility. …”

Image_1_Relevance of PUFA-derived metabolites in seminal plasma to male infertility.jpeg by Xiangfeng Chen (1548517)

“…In men with normozoospermia, higher levels of 7(R)-MaR1 (HR: 0.4 (95% CI [0.24, 0.64]) and 11,12-DHET (0.36 (95% CI [0.21, 0.58]) were significantly associated with a decreased risk of infertility, while higher levels of 17(S)-HDHA (HR: 2.32 (95% CI [1.44, 3.79]), LXA5 (HR: 8.38 (95% CI [4.81, 15.24]), 15d-PGJ2 (HR: 1.71 (95% CI [1.06, 2.76]), and PGJ2 (HR: 2.28 (95% CI [1.42, 3.7]) correlated with an increased risk of infertility. …”

Table_2_Relevance of PUFA-derived metabolites in seminal plasma to male infertility.docx by Xiangfeng Chen (1548517)

“…In men with normozoospermia, higher levels of 7(R)-MaR1 (HR: 0.4 (95% CI [0.24, 0.64]) and 11,12-DHET (0.36 (95% CI [0.21, 0.58]) were significantly associated with a decreased risk of infertility, while higher levels of 17(S)-HDHA (HR: 2.32 (95% CI [1.44, 3.79]), LXA5 (HR: 8.38 (95% CI [4.81, 15.24]), 15d-PGJ2 (HR: 1.71 (95% CI [1.06, 2.76]), and PGJ2 (HR: 2.28 (95% CI [1.42, 3.7]) correlated with an increased risk of infertility. …”

Table_3_Relevance of PUFA-derived metabolites in seminal plasma to male infertility.docx by Xiangfeng Chen (1548517)

“…In men with normozoospermia, higher levels of 7(R)-MaR1 (HR: 0.4 (95% CI [0.24, 0.64]) and 11,12-DHET (0.36 (95% CI [0.21, 0.58]) were significantly associated with a decreased risk of infertility, while higher levels of 17(S)-HDHA (HR: 2.32 (95% CI [1.44, 3.79]), LXA5 (HR: 8.38 (95% CI [4.81, 15.24]), 15d-PGJ2 (HR: 1.71 (95% CI [1.06, 2.76]), and PGJ2 (HR: 2.28 (95% CI [1.42, 3.7]) correlated with an increased risk of infertility. …”

Effects of H₂O₂ on the TGF-<i>β</i>1-induced association between Smad3 and Smad4. by Huchun Li (370357)

“…HEK293T cells were co-transfected with 0.5 µg of Flag-Smad3, 0.5 µg of HA-Smad4, and 0.15 µg of caT<i>β</i>RII plasmids, as indicated. 24 hours later, cells were treated with 200 µM of H₂O₂ for 2 hours, followed by immunoprecipitation and Western blotting, as indicated. …”

Image_1.TIF by Meng Li (79487)

“…HUVEC were pre-treated with acetate (10 mM), butyrate (5 mM) or propionate (10 mM) for 24 h and then stimulated with LPS (1 μg/ml) or TNFα (1 ng/ml) for 8 h. …”

Inhibitory Effect of Tanshinone IIA on Rat Hepatic Stellate Cells by Ya-Wei Liu (606320)

“…HSC-T6 cells were pretreated with Tan IIA (1, 3 and 10 µM), then induced by LPS (100 ng/ml). NF-κB activity was evaluated by the luciferase reporter gene assay. …”

Supplementary Material for: Serum Autotaxin Level Positively Associates with Metabolic Associated Fatty Liver Disease and Hyperuricemia in Postmenopausal Women by Zhang J. (2986470)

“…Serum level of autotaxin is significantly elevated in hyperuricemia group (257.3±60.9 vs. 214.5±49.4 ng/mL; P < 0.05), and positively correlated with uric acid level (P＜0.01). …”

Image_3.TIF by Meng Li (79487)

“…HUVEC were pre-treated with acetate (10 mM), butyrate (5 mM) or propionate (10 mM) for 24 h and then stimulated with LPS (1 μg/ml) or TNFα (1 ng/ml) for 8 h. …”

Image_2.TIF by Meng Li (79487)

“…HUVEC were pre-treated with acetate (10 mM), butyrate (5 mM) or propionate (10 mM) for 24 h and then stimulated with LPS (1 μg/ml) or TNFα (1 ng/ml) for 8 h. …”

Xenograft model of CML with the human cell line K562 in wild-type and E- and P-selectin knockout scid mice. by Daniel Wicklein (333203)

“…<p>Selectin deficiency dramatically increases survival of the animals after injection of 2×10⁶ K562 cells and decreases the number of leukemia cells in blood and bone marrow. …”

<i>headcase</i> affects the physiology of the prothoracic gland and the release of ecdysone. by Panagiotis Giannios (10113763)

“…The wing disc volume of <i>phmGal4/hdc</i>^<i>RI</i> and <i>phmGal4/hdc</i>^<i>R2</i> larvae is significantly lower (mean = 3.6μm³*10⁻⁶ and 3.5μm³*10⁻⁶) than the control (mean = 6.9 μm³*10⁻⁶ and 7.1 μm³*10⁻⁶ for the <i>phmGal4/+</i> and the <i>hdc</i>^{<i>BG00237/+</i>} respectively) and all mutant groups (mean = 7.9 μm³*10⁻⁶, 7.8 μm³*10⁻⁶ and 7.9 μm³*10⁻⁶, for the <i>hdc</i>^<i>43</i>, <i>hdc</i>^<i>50</i> and <i>hdc</i>^{<i>BG00237</i>} respectively). …”

(A): Orexin A inhibits propofol-induced neurite retraction by activation of phospholipase D. by Karin Björnström (118598)

“…OA increases the PKCε Ser⁷²⁹ phosphorylation compared to CCM, and this is reduced when PLD is blocked by FIPI, whereas propofol-treated cells showed a decrease in PKCε Ser⁷²⁹ phosphorylation that increased after FIPI treatment (n = 5). …”

Possible Gene Dosage Scenarios before and after the Acquisition of Imprinting by Andrew J Wood (24461)

“…</p><p>(C) A nonimprinted autosomal gene acquires imprinting without undergoing a recent duplication, resulting in a 50% decrease in active gene copy number (2:1). …”

Analysis of WT and <i>Abl</i> neuronal growth at RT and HT. by Lijuan Liu (136685)

Table_1_Effect of dietary protein content shift on aging in elderly rats by comprehensive quantitative score and metabolomics analysis.DOCX by Wenxuan Zheng (12524215)

“…Hence, in this study, 50, 25-month-old male rats were randomly divided into five groups: Control (basal diet), LP (low-protein diet with a 30% decrease in protein content compared to the basal diet), HP (high-protein diet with a 30% increase in protein content compared to the basal diet), Model 1 (switched from LP to HP feed at week 4), and Model 2 (switched from LP to HP feed at week 7). …”

Table_1_Nitrogen Isotope Sclerochronology—Insights Into Coastal Environmental Conditions and Pinna nobilis Ecology.xlsx by Melita Peharda (536604)