Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy by Chen-Hsueh Pai (828204)

“…The high salt-treated wild-type pregnant mice had shown unchanged maternal body weight, hypertension (MAP increase 15 mmHg), and decreased pup weight (~50%) and size (~24%), but these adverse effects were ameliorated in TXAS knockout (KO) mice. …”

Table_1.DOC by Hui Zhang (7197)

“…Therefore, current study was conducted to explore the ameliorating effect of icariin in thiram-induced TD chickens. A total of 180 broiler chicks were equally distributed in three groups; control, TD induced by thiram (50 mg/kg), and icariin group (treated with icariin @10 mg/kg). …”

Image_1_Intervention effects of low-molecular-weight chondroitin sulfate from the nasal cartilage of yellow cattle on lipopolysaccharide-induced behavioral disorders: regulation of... by Yuxuan Deng (4898617)

“…Surprisingly, compared to the LPS model group, the abundances of Streptococcus, Eisenbergiella, Vampirovibrio, Coprococcus, Enterococcus and Lachnoanaerobaculum were significantly increased in the intestines of mice in the CS-1 and CS-2 group, whereas those of Parabacteroides and Mycoplasma were significantly decreased. Altogether, this study provides a theoretical basis for the comprehensive utilization of agricultural and animal resources and the application of brain nutrition, anti-inflammatory, and LMWCS health products.…”

Supplementary materials: Comparing the performance of two-stage residual inclusion methods when using physician’s prescribing preference as an instrumental variable: unmeasured con... by Lisong Zhang (18296679)

“…Further, 2SRI was found to be robust to mild noncollapsibility with the percent bias less than 50%. As the level of unmeasured confounding increased, the ability to alleviate the noncollapsibility decreased. …”

DataSheet1_Safflower Polysaccharide Inhibits AOM/DSS-Induced Mice Colorectal Cancer Through the Regulation of Macrophage Polarization.DOC by Qun Wang (102815)

“…Taken together, all results suggested that SPS-1 could be a therapeutic option for the prevention and treatment of CRC.…”

Asthma Is Associated with Multiple Alterations in Anti-Viral Innate Signalling Pathways by Antonia L. Pritchard (627406)

“…Though decreased capacity to produce anti-viral interferons (IFNs) has been reported in asthma, a detailed analysis of the molecular events involved has not been undertaken.…”

AlgiMatrix™ Based 3D Cell Culture System as an In-Vitro Tumor Model for Anticancer Studies by Chandraiah Godugu (101721)

“…</p> <h3>Results</h3><p>IC₅₀ values for anticancer drugs were significantly higher in AlgiMatrix™ systems compared to 2D culture models. …”

Baseline characteristics of the study population. by Eun Sol Kang (18309844)

“…The study population comprised patients with at least one record of a principal diagnosis of breast cancer (ICD-10 code: C50) from the national health insurance claim database between 2010 and 2019. …”

Murine IL-21 plus rituximab prolongs the survival of SCID mice bearing disseminated lymphoma tumor cells. by Cecile M. Krejsa (426824)

“…<p>(<b>A, B</b>) SCID mice (n = 10/group) were injected i.v. with 10⁶ lymphoma cells and then treated with rituximab alone (20 µg on days 3, 7, 11, 15, 19), mIL-21 alone (100 µg days 1–5), or mIL-21 and rituximab. …”

Table1_The mechanism of oxymatrine on atopic dermatitis in mice based on SOCS1/JAK-STAT3 pathway.XLS by Xianwei Han (6452636)

“…And the expression of serum inflammatory factors, CD3 positive expression and JAK-STAT3 pathway protein in the model group were increased (p < .05), and the expression of suppressor of cytokine signaling 1 protein (p < .05) was decreased. Compared with the model group, the above pathological damage of the mice was reduced, and the serum inflammatory factors, JAK-STAT3 pathway protein, and CD3 positive expression were decreased as a dose-dependant manner (p < .05), and the expression of suppressor of cytokine signaling 1 protein was increased as a dose-dependent manner (p < .05). …”

Data_Sheet_1_Structural and functional changes of bioactive proteins in donor human milk treated by vat-pasteurization, retort sterilization, ultra-high-temperature sterilization,... by Ningjian Liang (5853227)

“…UHT did not alter osteopontin immunoreactivity, but Vat-PT and retort decreased it by ~50 and 70%, respectively. Freeze-thawing with homogenization, Vat-PT and UHT reduced lactoferrin's immunoreactivity by 35, 65, and 84%, respectively. …”

Resistance to Diet-Induced Obesity and Associated Metabolic Perturbations in Haploinsufficient Monocarboxylate Transporter 1 Mice by Sylvain Lengacher (499047)

“…Body composition analysis revealed that reduced weight gain in <i>MCT1</i>^+/− mice was due to decreased fat accumulation (50.0% less after 9 months of HFD) notably in liver and white adipose tissue. …”

Presentation_1_Chronic Exercise Improves Mitochondrial Function and Insulin Sensitivity in Brown Adipose Tissue.pdf by Natalia de las Heras (120375)

“…Male Wistar rats were divided into two groups: (1) control group (C; n = 10) and (2) exercise-trained rats (ET; n = 10) for 8 weeks on a motor treadmill (five times per week for 50 min). …”

Knockdown of micro-RNA-125 reverses the mesenchymal phenotype and increases the drug sensitivity in BxPC3-GZR cells. by Alakesh Bera (493669)

“…Images were taken after crystal violet staining of migrated cells and the data was plotted as a graph (Bar = 50 µm). <b>F.</b> Knockdown of miR-125b increases response to gemcitabine. …”

Trans10,cis12 conjugated linoleic acid inhibits proliferation and migration of ovarian cancer cells by inducing ER stress, autophagy, and modulation of Src by Mian M. K. Shahzad (4759608)

“…RNA sequencing was conducted using the Illumina platform and apoptosis was measured using a flow cytometry assay. t10,c12 CLA (IC₅₀, 7 μM) inhibited proliferation of ovarian cancer cell lines SKOV-3 and A2780. c9,t11 CLA did not attenuate the proliferation of these cells. …”

Data_Sheet_1_Structural and functional changes of bioactive proteins in donor human milk treated by vat-pasteurization, retort sterilization, ultra-high-temperature sterilization,... by Ningjian Liang (5853227)

“…UHT did not alter osteopontin immunoreactivity, but Vat-PT and retort decreased it by ~50 and 70%, respectively. Freeze-thawing with homogenization, Vat-PT and UHT reduced lactoferrin's immunoreactivity by 35, 65, and 84%, respectively. …”

DataSheet_1_Clinical characteristics and the influence of rs1800470 in patients with Camurati-Engelmann disease.docx by Hanting Liang (9348707)

“…All patients manifested bone pain and decreased subcutaneous fat tissue. Inflammatory markers increased in over 60% of patients, and the median erythrocyte sedimentation rate (ESR) was 1.40 (0.50~3.67) of the upper limit of normal (ULN), and the median high sensitivity C reactive protein (hsCRP) was 1.71 (0.48~12.56) of ULN. …”

3-MA and Atg7 siRNA increase the level of apoptosis in MDA-MB-231 and BT-549 cells. by Weibin Wu (335758)

“…<p>(A) 3-MA and Atg7 siRNA decreased the protein level of Bcl-2 and increased that of Bax in MDA-MB-231 and BT-549 cells, as shown by western blotting. …”

Assay controls for primary screening. by Nermina Vejzagić (6269618)

“…Recovery of juveniles was assessed on day 7 (168 h) from the initial drug screening. Data represent the mean ± standard deviation for n = 38 per time point for a total of B) The representative phenotype of juveniles treated with 30 μM PZQ and 0.3% v/v DMSO. 10x magnification; h: hours; v/v: volume by volume.…”

The effect of rapid wall movement on internal flow. by Shinji Deguchi (228220)

“…If a perturbation <i>b_c</i> with a positive value is slowly given to the steady state (ii), such enlargement of the constriction weakens the convective acceleration and hence decreases the instantaneous velocity <i>U_c</i> with the appearance of a negative perturbation velocity <i>u_c</i> and a consequent positive perturbation pressure <i>p_c</i>. …”