Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial by Michael Eddleston (53745)

“…</p><h3>Methods and Findings</h3><p>We performed a double-blind randomised placebo-controlled trial of pralidoxime chloride (2 g loading dose over 20 min, followed by a constant infusion of 0.5 g/h for up to 7 d) versus saline in patients with organophosphorus insecticide self-poisoning. …”

Supplementary Material for: Endothelial Dysfunction of the Peripheral Vascular Bed in the Acute Phase after Ischemic Stroke by Scherbakov N. (4129753)

“…A decreased RHI was observed in cardioembolic and lacunar infarcts and stroke of undetermined etiology (1.7 ± 0.4, 1.8 ± 0.5 and 1.7 ± 0.3, p < 0.0001). …”

Determinants of coronary flow reserve in non-diabetic patients with chest pain without myocardial perfusion defects by Helena U. Westergren (758365)

“…Secondly, we investigated association between cardiovascular parameters and decreased CFR in a sex specific manner.…”

The development of the glomerulocystic phenotype is progressively associated with loss of primary cilium. by Anna Iervolino (708944)

“…<p>Representative pictures of renal cortex from 50 days old Ctr (B) and Dicer cKO mice (A, C, D) stained for α-Acetylated Tubulin (green) and counterstained with Dapi (blue). …”

The PI3K/Akt- and NO-related pathways contribute to EPC tube formation affected by oxLDL. by Feng-Yen Lin (143413)

“…<p>(A and B) EPCs were treated for 2 hours with 0–50 μg/mL oxLDL, then eNOS and Akt activation (phosphorylation) was analyzed by Western blot. …”

Small molecule inhibitors of GSK-3β impede VEEV replication. by Kylene Kehn-Hall (45085)

“…<p><b>A</b>) U87MG astrocytes were treated with BIO (10, 5, 2.5, or 1.25 µM) and cell viability assayed 24 hours later by CellTiter Glo Assay (Promega). …”

Triptolide induces tRXRα degradation and AKT inactivation through activation of p38. by Na Lu (325317)

“…Triptolide-induced time-dependent phosphorylation of p38, JNK and Erk1/2 was compared to its effect on decreasing AKT phosphorylation and PARP cleavage. (B) HepG2 cells were treated with 50 nM triptolide for 9 h with or without p38 inhibitor SB203580 (10 µM), JNK inhibitor SP600125 (10 µM) or Erk1/2 MAPK inhibitor PD98059 (10 µM). …”

Benzodiazepine prescribing for children, adolescents, and young adults from 2006 through 2013: A total population register-linkage study by Anna Sidorchuk (313137)

“…Prescribing patterns were established in relation to duration (3 months, >3 to ≤6 months, or >6 months), dosage (<0.5 defined daily dosage [DDD]/day, ≥0.5 to <1.5 DDD/day, or ≥1.5 DDD/day), and “user category” (“regular users” [≥0.5 to <1.5 DDD/day for ≥1 year], “heavy users” [≥1.5 DDD/day for ≥1 year], or otherwise “occasional users”). …”

Simulation results of rate-dependent APD changes in six different conditions. by Young-Seon Lee (565899)

“…<p>APs were drawn in the steady-state condition at the pacing rates of 2 Hz (A) and 1 Hz (B). (C) The relationships between APD and BCL were drawn at the control condition (<b>a</b>), I_CaL decreased by 50% (<b>b</b>), 70% (<b>c</b>), I_K1 increased by 100% (<b>d</b>), the PeAF condition with I_CaL decreased by 50% (<b>e</b>), and the PeAF condition (<b>f</b>) with I_CaL decreased by 70%.…”

Data_Sheet_1_Influence of Older Age and Other Risk Factors on Pneumonia Hospitalization in Switzerland in the Pneumococcal Vaccine Era.docx by Werner C. Albrich (3177693)

“…Older age with both age cut-offs were associated with increased LOS (≥50 years: aRR: 1.19 and 1.24, respectively; age ≥65 years: aRR: 1.60 and 1.20, respectively; p < 0.001 for all) and mortality (≥50 years: aOR: 4.73 and 2.84, respectively; age ≥65 years: aOR: 2.38 and 2.69, respectively, p < 0.001 for all) in patients with a pneumonia and pneumococcal pneumonia diagnosis, respectively. …”

DataSheet1_Long-term change of the eruption activities of Sakurajima volcano, Japan, inferred from the fallout tephra deposits.PDF by Ayumu Nishihara (14173077)

“…We define three eruption stages of Stage 1 (30–24 ka), Stage 2 (12.8–4.8 ka), and Stage 3 (4.5 ka–present), based on a major hiatus and shifting of the volcanic centers. …”

Table_1_Temporal trends in cardiovascular health among Chinese urban children and adolescents, 2004–2019 pre-pandemic COVID-19.docx by Pei Xiao (466657)

“…Notably, the proportion of ideal body mass index (2004, 77.5%; 2019, 59.7%) and blood pressure (2004, 73.6%; 2019, 67.3%) continuously decreased from 2004 to 2019. …”

DataSheet3_Long-term change of the eruption activities of Sakurajima volcano, Japan, inferred from the fallout tephra deposits.PDF by Ayumu Nishihara (14173077)

“…We define three eruption stages of Stage 1 (30–24 ka), Stage 2 (12.8–4.8 ka), and Stage 3 (4.5 ka–present), based on a major hiatus and shifting of the volcanic centers. …”

Table1_Long-term change of the eruption activities of Sakurajima volcano, Japan, inferred from the fallout tephra deposits.XLSX by Ayumu Nishihara (14173077)

“…We define three eruption stages of Stage 1 (30–24 ka), Stage 2 (12.8–4.8 ka), and Stage 3 (4.5 ka–present), based on a major hiatus and shifting of the volcanic centers. …”

Data_Sheet_1_Enhancing β-Carotene Production in Escherichia coli by Perturbing Central Carbon Metabolism and Improving the NADPH Supply.pdf by Yuanqing Wu (401810)

“…Deletion of the zwf gene increased the resultant strain's β-carotene production and content by 5.1 and 32.5%, respectively, relative to the values of strain ZF43ΔgdhA, but decreased the biomass by 26.2%. …”

DataSheet2_Long-term change of the eruption activities of Sakurajima volcano, Japan, inferred from the fallout tephra deposits.PDF by Ayumu Nishihara (14173077)

“…We define three eruption stages of Stage 1 (30–24 ka), Stage 2 (12.8–4.8 ka), and Stage 3 (4.5 ka–present), based on a major hiatus and shifting of the volcanic centers. …”

Characteristics induced by 2 weeks exposure of SRA01/04 cells to low-doses of H₂O₂. by Zi-Feng Zhang (341807)

“…<p>A. Shows that cell viability (Left) of SRA01/04 cells decreases with increasing concentrations of H₂O₂ as measured by the MTT assay (Mean± SD; n = 5.). …”

Diagram illustrates the potential actions of Astragaloside IV on Fas/Fas L apoptotic pathway. by Mi Hye Kim (543923)

Fig-7. The development of the glomerulocystic phenotype is progressively associated with loss of primary cilium. by Anna Iervolino (6712642)

“…<div>Fig-7 Representative pictures of renal cortex from 50 days old Ctr (B) and Dicer cKO mice (A, C, D) stained for α-Acetylated Tubulin (green) and counterstained with Dapi (blue). …”

Changes in endocannabinoids and <i>N</i>-acylethanolamines after mood inductions by ambiance and moderate alcohol consumption. by Ilse C. Schrieks (512142)