Data_Sheet_1_The role of GPD1L, a sodium channel interacting gene, in the pathogenesis of Brugada Syndrome.PDF by Alexander M. Greiner (18852223)

“…</p>Objective<p>We sought to re-assess the genetic underpinnings of BrS in a large mutligenerational family with a putative mutation in GPD1L that affects surface membrane expression of Na_V1.5 in vitro.…”

Micelle and Inverse Micelle Structure Driven Viscoelasticity and Phase Separation in 2‑Isobutoxyethanol–Water Mixtures: Insights from All-Atom Simulations by Mayank Dixit (7879364)

“…We observed the presence of the inverse micelle structure in <i>x</i>_IBE = 0.5 and micelle structures in <i>x</i>_IBE = 0.1. …”

Data Sheet 1_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …”

Data_Sheet_1_Beyond QuantiFERON-TB Results, the Added Value of a Weak Mitogen Response.pdf by Marine Jacquier (578627)

“…</p>Methods<p>Retrospective, case-control study in hospitalized patients who underwent QFT testing in two hospitals between 2016 and 2019. We defined two groups of cases with either negative [interferon (IFN)-γ ≤ 0.5 IU/ml, official threshold] or weak (0.5–2 IU/ml) mitogen response, and one group of controls with normal (>2 IU/ml) mitogen response.…”

Image_1_Trends in radiotherapy administration in the management of hepatocellular carcinoma: Analysis of a Korean tertiary hospital registry of hepatocellular carcinoma patients di... by Bong Kyung Bae (8736945)

“…With the technical developments, the overall survival (OS) of patients who received radiotherapy as initial management increased significantly (5-year OS: from 5.4% to 30.1%), and the OS difference between patients who did and did not receive radiotherapy as initial management significantly decreased (ratio of restricted mean survival time: from 0.383 to 0.544).…”

Data_Sheet_1_High blood viscosity in acute ischemic stroke.PDF by Jihoon Kang (816884)

“…At an oscillatory frequency of 10 rad/sec, blood viscosity differed significantly between the ischemic stroke (24.2 ± 4.9 centipoise, cP) and stroke mimic groups (17.8 ± 6.5 cP, p < 0.001). This finding was consistent at different oscillatory frequencies (134.2 ± 46.3 vs. 102.4 ± 47.2 at 1 rad/sec and 39.2 ± 11.5 vs. 30.4 ± 12.4 at 5 rad/sec, Ps < 0.001), suggesting a relationship between decreases in viscosity and shear rate. …”

Image_1_The Predictive Value of Estrogen Receptor 1 on Adjuvant Chemotherapy in Locally Advanced Colorectal Cancer: A Retrospective Analysis With Independent Validation and Its Pot... by Shu-Biao Ye (4264795)

“…Downregulation of ESR1 was related with enhanced chemosensitivity to 5-FU in CRC cell lines, while upregulation of ESR1 was correlated with decreased chemosensitivity.…”

Table_1_After-Effects of Thixotropic Maneuvers on Chest Wall and Compartmental Operational Volumes of Healthy Subjects Using Optoelectronic Plethysmography.DOCX by Illia Nadinne Dantas Florentino Lima (7617188)

“…Thus, after performing thixotropic maneuvers, OEP may also provide evidence regarding the history-dependent properties of these muscles. We studied the after-effects of different thixotropic conditionings on chest wall (CW) and compartmental operational volumes of 28 healthy subjects (25.5 ± 2.2 years, FVC_%pred 94.8 ± 5.5, and FEV₁_%pred 95.5 ± 8.9) using OEP. …”

Image_2_CD2 Regulates Pathogenesis of Asthma Induced by House Dust Mice Extract.JPEG by Tanwir Hashem (8825765)

“…Interestingly, Il13 but not Il4 or Il5 gene expression in the lungs was dramatically decreased in HDME-exposed Cd2^−/− mice. …”

BMI (crude values and <i>z</i>-scores) age trend with 95% confidence intervals by haplotypes (CCT/x, red, vs carriers of the most prevalent haplotype, TTC, blue) in boys and girls. by Francesco Gianfagna (440763)

Changes in air quality during the first-level response to the COVID-19 pandemic in Shanghai Municipality, China by Bai, Yang

“…The results showed that air quality improved significantly During-FLR compared with Pre-FLR, with the concentrations of PM2.5, PM10, SO2, NO2, and CO all decreasing significantly. …”
Get full text
Get full text
Get full text

Table_1_Water mass mixing contributes dynamics of dissolved organic matter in Kuroshio-Oyashio confluence region.docx by Yasong Wang (1406251)

“…The biological index (BIX) decreases with increasing depth, indicating decreasing in-situ production of plankton downwards. …”

DataSheet_1_Single-Cell Transcriptomics Reveals Peripheral Immune Responses in Anti-Synthetase Syndrome-Associated Interstitial Lung Disease.pdf by Lili Zhu (219363)

“…</p>Methods<p>We performed single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) from 5 patients with ASS-ILD and 3 healthy donors (HDs). …”

Genetic Analysis of a Rat Model of Aerobic Capacity and Metabolic Fitness by Yu-yu Ren (469951)

“…Here we conduct the first in-depth pedigree and molecular genetic analysis of these lines, the high capacity runners (HCR) and low capacity runners (LCR). …”

Overdiagnosis and overtreatment of thyroid cancer: A population-based temporal trend study by Sabrina Jegerlehner (4110049)

“…</p><p>Conclusions</p><p>We observed a large increase in the incidence of thyroid cancer, limited to papillary and early stage tumors, with a three- to four-fold parallel increase in thyroidectomy. …”

Image_1_Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model.tif by Rinku Dutta (2131366)

“…Tumors and spleens were analyzed by flow cytometry for the distinct immune cell populations affected by the treatment, in addition to RT-PCR for tumor samples. We demonstrated the combination treatment decreases tumor growth, thus increasing the effectiveness of the CB. …”

Image_2_Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Uses the VraSR Regulatory System to Modulate Autophagy for Increased Intracellular Survival in Macrophage-Like C... by Yuanyuan Dai (714579)

“…Mu3ΔvraSR-infected RAW264.7 cells also showed decreased transcription of autophagy-related genes Becn1 and Atg5, decreased LC3-II turnover and increased p62 degradation, and fewer visible punctate LC3 structures. …”

Table_1_Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Uses the VraSR Regulatory System to Modulate Autophagy for Increased Intracellular Survival in Macrophage-Like C... by Yuanyuan Dai (714579)

“…Mu3ΔvraSR-infected RAW264.7 cells also showed decreased transcription of autophagy-related genes Becn1 and Atg5, decreased LC3-II turnover and increased p62 degradation, and fewer visible punctate LC3 structures. …”

Altered glucose metabolism and hypoxic response in alloxan-induced diabetic atherosclerosis in rabbits by Yunosuke Matsuura (513639)

“…Diabetic atherosclerosis was induced in rabbit ilio-femoral arteries by injecting alloxan (100 mg/kg), injuring the arteries using a balloon, and feeding with a 0.5% cholesterol diet. We histologically assessed the atherosclerotic lesion development, cellular content, pimonidazole positive-hypoxic area, the nuclear localization of hypoxia-inducible factor-1α, and apoptosis. …”

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin by Vanniarajan Ayyasamy (205064)

“…We developed a MitoExpress array for rapid analysis of all known nuclear genes encoding the mitochondrial proteome. …”