KLF2 (kruppel-like factor 2 [lung]) regulates osteoclastogenesis by modulating autophagy by Dipranjan Laha (6491537)

“…To investigate the specific role of KLF2 in autophagy, osteoclastic differentiation was induced in monocytes in presence or absence of the autophagy inhibitor 3-methyladenine (3-MA), KLF2 inducer geranylgeranyl transferase inhibitor (GGTI298), and adenoviral overexpression of KLF2. We found that the number of autophagic cells and multinucleated osteoclasts were significantly decreased in presence of 3-MA, GGTI298, and KLF2 overexpressed cells indicating involvement of KLF2 in these processes. …”

DataSheet_1_Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.docx by Fuliang Zong (13827097)

“…To test this, colony stimulating factor 2 receptor alpha (Csf2ra) knockout (KO) mice that lack GM-CSF signaling and wild-type (WT) mice models of intratracheal exposure to a lethal dose (2× LD₅₀) of RT were established. …”

Effects of three sesquiterpene compounds from volatile oil of <i>Dalbergia odorifera</i> T. Chen on pERK1/2, ERK1/2, PPARγ and HO-1 expression in LPS-stimulated RAW264.7 macrophage... by Xiang Li (114679)

“…<p>(A). LPS co-incubation induced significant increase of pERK1/2 expression, the ratio of pERK1/2 to ERK1/2 was higher than that in the control group (*<i>p</i><0.05). 50 µM ENL attenuated the increased ratio of pERK1/2 to ERK1/2, while 50 µM SDL suppressed this ratio compared to LPS treated alone (#<i>p</i><0.05), and RDL had no effect on the increased ratio. …”

Trajectory of disability and quality-of-life in non-geriatric and geriatric survivors after severe traumatic brain injury by Chiara S. Haller (3689263)

“…</p> <p><i>Methods</i>: Patients ≥ 16 years who sustained a severe TBI (Abbreviated Injury Scale of the head region > 3) were included in this prospective, multi-centre study. …”

Deuteration of Perylene Enhances Photochemical Upconversion Efficiency by Andrew Danos (1362450)

Effects of the structure-based peptides on <i>C</i>. <i>elegans</i> survival infected by <i>P</i>. <i>aeruginosa</i>. by Yichen Zhang (473963)

“…<p>(<b>A</b>) The T2SS is critical to the virulence of <i>P</i>. …”

Image_2_Time dependent effects of prolonged hyperglycemia in zebrafish brain and retina.jpeg by Cassie J. Rowe (13388265)

“…After 8-weeks, RelA, GAD, and TH were significantly elevated in both tissues; IKK and GFAP levels were also elevated, though not significantly. ZO-1 and claudin-5 levels osmotically decreased in retina but displayed an increasing trend in glucose-treated brains. …”

Data Sheet 3_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. …”

Image2_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Data Sheet 2_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. …”

DataSheet_1_Pharmacodynamic and Metabolomics Studies on the Effect of Kouyanqing Granule in the Treatment of Phenol-Induced Oral Ulcer Worsened by Sleep Deprivation.docx by Pan Chen (385477)

“…KYQG significantly reduced the levels of 5-HT and GABA in serum, and only decreased the 5-HT level in brain tissue after phenol injury followed by sleep deprivation. …”

Table 1_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.docx by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. …”

Table1_Molecular subtyping of acute myeloid leukemia through ferroptosis signatures predicts prognosis and deciphers the immune microenvironment.XLS by Denggang Fu (5082062)

“…<p>Acute myeloid leukemia (AML) is one of the most aggressive hematological malignancies with a low 5-year survival rate and high rate of relapse. …”

Data Sheet 1_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. …”

Table4_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Table3_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Epidemiological Study of RRT-Treated ESRD in Nanjing - A Ten-Year Experience in Nearly Three Million Insurance Covered Population by Yu-Chen Han (2149615)

“…</p><p>Results</p><p>The UEBMI population in Nanjing increased from 1,301,882 in 2005 to 2,921,065 in 2014, among which a total of 5,840 subjects developed ESRD and received RRT. …”

Image4_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Image1_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Image3_Molecular subtyping of acute myeloid leukemia through ferroptosis signatures predicts prognosis and deciphers the immune microenvironment.TIF by Denggang Fu (5082062)

“…<p>Acute myeloid leukemia (AML) is one of the most aggressive hematological malignancies with a low 5-year survival rate and high rate of relapse. …”