image8_Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials.jpeg by Yanli Sun (1559716)

“…According to published data, the rates of SD, PD, CR and PR were 27.4%, 37.6%, 3.5%, and 5.7%, respectively, which is not very satisfactory. …”

image11_Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials.jpe... by Yanli Sun (1559716)

“…According to published data, the rates of SD, PD, CR and PR were 27.4%, 37.6%, 3.5%, and 5.7%, respectively, which is not very satisfactory. …”

Table_1_Impact of climate warming on soil microbial communities during the restoration of the inner Mongolian desert steppe.DOCX by Jirong Qiao (19341820)

“…This inevitability highlights the urgent need to study the effect of temperature on grassland soil microbial communities, given their critical ecological functions.</p>Methods<p>Here, we assessed the effects of heavy grazing (control), grazer exclosure, and grazer exclosure plus warming by 1.5°C on soil microbial community diversity and network properties as well as their relationships to soil physicochemical properties.…”

Table_1_Artesunate Suppresses Choroidal Melanoma Vasculogenic Mimicry Formation and Angiogenesis via the Wnt/CaMKII Signaling Axis.doc by Bochao Geng (11267529)

“…Recent studies have shown that the Wnt5a/calmodulin-dependent kinase II (CaMKII) signaling pathway has a close correlation with angiogenesis and VM formation. …”

image1_Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials.jpeg by Yanli Sun (1559716)

“…According to published data, the rates of SD, PD, CR and PR were 27.4%, 37.6%, 3.5%, and 5.7%, respectively, which is not very satisfactory. …”

Supplementary Material for: Management and Survival of Pleural Mesothelioma: A Record Linkage Study by Carioli G. (4838469)

“…OS was 45.4% at 1 year, 24.8% at 2 years, and 9.6% at 5 years (median 11 months). OS decreased with age, and was higher for those who underwent surgery, but not for those treated with chemotherapy. …”

image10_Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials.jpe... by Yanli Sun (1559716)

“…According to published data, the rates of SD, PD, CR and PR were 27.4%, 37.6%, 3.5%, and 5.7%, respectively, which is not very satisfactory. …”

Table_1_Implementation of Nurse-Led, Goal-Directed Lung Physiotherapy for Older Patients With Sepsis and Pneumonia in the ICU.DOCX by Jianhua Sun (187443)

“…Patients in the treatment group had a significantly shorter duration of mechanical ventilation [5 (4, 6) vs. 5 (4, 8) days; P = 0.045], and a lower risk of intensive care unit (ICU) mortality [14.5% (24/166) vs. 28.7% (25/87); P = 0.008] and 28 day mortality [15.1% (25/166) vs. 31% (27/87); P = 0.005] compared with those in the control group. …”

A Systems Toxicology Approach to Elucidate the Mechanisms Involved in RDX Species-Specific Sensitivity by Christopher M. Warner (2064109)

“…Interspecies uncertainty factors in ecological risk assessment provide conservative estimates of risk where limited or no toxicity data is available. We quantitatively examined the validity of interspecies uncertainty factors by comparing the responses of zebrafish (<i>Danio rerio</i>) and fathead minnow (<i>Pimephales promelas</i>) to the energetic compound 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), a known neurotoxicant. …”

Table_2_Are Cognitive Changes in Hereditary Spastic Paraplegias Restricted to Complicated Forms?.DOCX by Laís Alves Jacinto-Scudeiro (6730991)

“…</p><p>Results: Fifty four patients with genetically confirmed HSP diagnosis, 36 with spastic paraplegia type 4 (SPG4), 5 SPG11, 4 SPG5, 4 cerebrotendinous xanthomatosis (CTX), 3 SPG7 and 2 SPG3A, and 10 healthy, unrelated control subjects, with similar age, sex, and education participated in the study. …”

Image_9_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Image_1_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Biological Responses to Perfluorododecanoic Acid Exposure in Rat Kidneys as Determined by Integrated Proteomic and Metabonomic Studies by Hongxia Zhang (164388)

“…Furthermore, the profiles of free amino acids in the PFDoA treated groups were investigated quantitatively by high-coverage quantitative iTRAQ-LC MS/MS, which showed levels of sarcosine, asparagine, histidine, 1-methylhistidine, Ile, Leu, Val, Trp, Tyr, Phe, Cys, and Met increased markedly in the 0.5 mg dosed group, while homocitrulline, α-aminoadipic acid, β-alanine, and cystathionine decreased.…”

Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx by Hongliang Gu (21671054)

“…Compared to current, under the SSP1-2.6 and SSP5-8.5 climate scenarios, the moderately suitable distribution area expanded by 1.47% and 0.89%, respectively (averaging 5.53% across four time periods), while the highly suitable area decreased by 0.04% and 0.21%. …”

datasheet1_Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials.... by Yanli Sun (1559716)

“…According to published data, the rates of SD, PD, CR and PR were 27.4%, 37.6%, 3.5%, and 5.7%, respectively, which is not very satisfactory. …”

Hydrogen extends <i>Caenorhabditis elegans</i> longevity by reducing reactive oxygen species by Miao Zhang (17216)

“…Our results showed that the lifespans of the N2, <i>sod-3</i> and <i>sod-5</i> mutant strains were extended by approximately 22.7%, 9.5%, and 8.7%, respectively, after hydrogen treatment, but hydrogen had no effect on the lifespans of the <i>daf-2</i> and <i>daf-16</i> mutant strains. …”

Soil Respiration Rate and Climatic Parameters from Mixed and Broad-leaved forest sites from Bhutan, Eastern Himalayas for 2015 by Norbu Wangdi (3351200)

“…Measured temperature sensitivity of Rh was similar at the mixed and broadleaved forest site (<i>Q₁₀</i> 2.2- 2.3) under intermediate soil moisture but decreased (<i>Q₁₀</i> 1.5 at both sites) in dry soil. …”

DataSheet_1_Artesunate Suppresses Choroidal Melanoma Vasculogenic Mimicry Formation and Angiogenesis via the Wnt/CaMKII Signaling Axis.zip by Bochao Geng (11267529)

“…Recent studies have shown that the Wnt5a/calmodulin-dependent kinase II (CaMKII) signaling pathway has a close correlation with angiogenesis and VM formation. …”

OSTEOTOMY AT THE BASE OF FEMORAL NECK AND OSTEOPLASTY FOR THE TREAMENT OF SCFE by LARISSA MARTINS GARCIA (14108288)

“…No differences were observed between the SCFE and control cohort for the functional scores (HHS, 94 ± 7 vs 100 ± 1, p = 0.135); except for ROM, with increased internal rotation (37.3º ± 9.4º vs 28.7º ± 8.2º, p < 0.001), and strength, with decreased abduction torque (75.5 ± 36.9 Nm/Kg vs 88.5 ± 27.6 Nm/Kg, p = 0.045) in the SCFE cohort. …”

Table_1_Artesunate Suppresses Choroidal Melanoma Vasculogenic Mimicry Formation and Angiogenesis via the Wnt/CaMKII Signaling Axis.doc by Bochao Geng (11267529)

“…Recent studies have shown that the Wnt5a/calmodulin-dependent kinase II (CaMKII) signaling pathway has a close correlation with angiogenesis and VM formation. …”