Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

Subjects:

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

“…<i>Immediate ART</i> increased the 5-year HIV care budget from $801.9M to $812.6M compared to <i>ART<350/μL</i>.…”

Stress can increase or decrease anxiety depending on the timing of the stressor by Jason Snyder (96580)

Lower signal-to-noise ratio leads to decreased peak assignment. by Travis S. Hughes (779495)

Transepithelial resistance of NHBE decreases significantly after PAA exposure. by Ellie S. Burns (21246537)

Ageing results in an abrupt decrease in overall neurogenesis in the mouse DG. by Joana Gil-Mohapel (462002)

“…(C) An estimation of overall neurogenesis based on the total number of BrdU-positive cells that survived the 42-day period multiplied by the proportion of BrdU-positive cells that acquired a mature neuronal phenotype indicates an age-induced significant and abrupt decrease in the overall number of new neurons. *** <i>p</i> < 0.001 between 1.5 and 3 months and between 3 and 6 months. …”

Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis by Santiago Avila-Rios (3160959)

Subjects:

Anti-CXCR3 group decreased number of specific CD8⁺ T cells as well as polyfunctionality after infection with <i>T</i>. <i>cruzi</i>. by Camila Pontes Ferreira (6194006)

Decrease in GABA_B expression in APP mice. by Ksenia V. Kastanenka (3692380)

Rap1A knockdown <i>in vitro</i> impairs steady state monolayer integrity and decreases transepithelial electrical resistance. by Erika S. Wittchen (256700)

Phosphocreatine and ATP were decreased in the hearts CCCP-administered rats. by Akira Kawamoto (444329)

“…<p>(A) Representative images of <i>in situ</i> cardiac ³¹P magnetic resonance spectra. ppm, parts per million. …”

Semi-log plot of the FIFA countries ranked by their decreasing “order of importance” through the FIFA coefficient; the best 5-parameter function, Eq (5), is shown. by Marcel Ausloos (748325)

“…<p>Semi-log plot of the FIFA countries ranked by their decreasing “order of importance” through the FIFA coefficient; the best 5-parameter function, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166011#pone.0166011.e005" target="_blank">Eq (5)</a>, is shown.…”

Supplementary Material for: Platelet Decreases following Continuous Renal Replacement Therapy Initiation as a Novel Risk Factor for Renal Nonrecovery by Griffin B.R. (8570007)

“…<b><i>Results:</i></b> Time to RRT independence censored for death was achieved less frequently in patients with low platelet nadir (hazard ratio [HR] 0.77, confidence interval [CI] 0.66–0.91) and in those with >50% platelet decrease (HR 0.84, CI 0.72–0.97). RRT-free days were lower in both low platelet nadir (odds ratio [OR] 0.94, CI 0.90–0.97) and >50% platelet decrease (OR 0.91, CI 0.88–0.95). …”

Protection of Aβ-mediated neuronal cell death by sRAGE, pyridoxamine or ALT-711 through decreasing RAGE levels. by Kyunghee Byun (162379)

“…(D) *, The number of the triple-labeled cells (AGE/albumin/Iba-1 positive cells) significantly increased in whole EC area of Aβ injected rat brain but decreased dramatically in Aβ/sRAGE treated rat brain (p<0.01). …”

Decreased echinocandin susceptibility in <i>Candida parapsilosis</i> causing candidemia and emergence of a pan-echinocandin resistant case in China by Yating Ning (11264310)

Ivermectin significantly decreases <i>L</i>. <i>loa</i> mf in BALB/c mice. by Rene Bilingwe Ayiseh (6900296)

Both with somatic and with dendritic stimulation, pyramidal cell burst firing decreases as the apical dendrite becomes shorter. by Ronald A. J. van Elburg (80591)

Both with somatic and with dendritic stimulation, pyramidal cell burst firing decreases as the apical dendrite becomes shorter. by Ronald A. J. van Elburg (80591)

FOXO3a decreases expression of ER-regulated genes and increases CDK inhibitors in MCF7-FO breast tumors by Yiyu Zou (47196)

Transaldolase deficiency causes a starvation-like response that decreases animal fat content and rewires lipid metabolism gene expression. by Christopher F. Bennett (3875731)

“…<p><b>(A)</b> Intestinal fat staining decreases from RNAi knockdown of <i>tald-1</i> or <i>cco-1</i>. …”