Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-5 by Hong Yang (37298)

SARS-CoV-2 decreases excitatory synapses, while influenza A does not induce cell death in BCO. by Pinar Mesci (14053895)

Statistically significant union pathways refer to the miRNAs with a decreased expression on day 1. by Morgana Lüdtke Azevedo (15285409)

25OHD₃ does not induce vascular calcification in CYP27B1^-/- mice with CKD. by Noelia Torremadé (3687523)

25OHD₃ restores calcium and PTH levels in CYP27B1^-/- mice with CKD. by Noelia Torremadé (3687523)

SIRT1 is involved in the attenuation of H₂O₂-induced senescence by resveratrol. by Yasuo Ido (172159)

ING1 is one of the miR-371-5p targets and negatively regulated by miR-371-5p. by De He (497662)

Reduced autophagy, decreased survival, larger infarct areas, compromised cardiac function and contraction, and impaired angiogenesis in <i>AGGF1</i>^<i>+/-</i> knockout m... by Qiulun Lu (302045)

AMPK activation increases FOXO3 protein expression. by Yasuo Ido (172159)

Data Sheet 5_Phosphodiesterase 7: a potential novel therapeutic target in ovarian cancer.pdf by Nayara Gusmão Tessarollo (18228556)

“…</p>Results and discussion<p>MTT assays revealed that while BRL 50481 reduced metabolic cellular viability (MCV) in A2780 (IC50 = 200 μM), its combination with PTX decreased MCV in both lines, reducing PTX IC50 by 103- and 625-fold in A2780 and OVCAR3, respectively. …”

DMB treatment improved neurological deficit and decreased infarct volume 24 h after MCAO. by Huinan Zhang (849524)

Inhibition of IL-17A at tumor sites decreases the intratumoral microvessel density. by Keiji Hayata (277090)

“…<p>(A) The endothelial maker CD31-stained sections of tumor tissue are shown in Ad-SNC and Ad-si-IL-17 treatment models, Ad-si-IL-17 treatment decreased the intratumoral microvessel density compared with Ad-SNC. …”

The material parameters of the 50 MPa concrete for the simulations [26]. by Xiaochao Jin (3993236)

Image_5_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOTCH1, MKI67, OCT4, and MUC5AC via HIF1A Upregulation in Human Bronchial Epithelial Cells.TIF by Yung-Yu Yang (9343376)

“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”

NREM 1/f slopes calculated from Power Spectrum Densities (PSDs) have a robust nocturnal rhythm at low frequencies that are initially flattened during spontaneous oxycodone withdraw... by Michael Gulledge (20577135)

Effect of the Hill coefficient on estimates of <i>ε</i>_max (left column) and IC₅₀ (right column) for the logistic model with drug applied to the growth rate <... by Hope Murphy (8843516)

Partial correlation of <i>ε</i>_max (left column) and IC₅₀ (right column) estimates at 10 days and 20 days (first and second bar of each color, respectively) o... by Hope Murphy (8843516)

3D snapshots of the tumor system with single-agent BHQ880 treatment at (a) time step 40, (b) time step 50 and (c) time step 120. by Minna Qiao (836556)

E₅₀ values. by Junxia Zhou (14381598)

High-throughput drug screen reveals HDAC and proteasome inhibitors as potent drug classes against synovial sarcoma. by Aimée N. Laporte (3617987)

“…(C) Compounds that brought about greater than 90% decreased relative cell viability were scored as 1 (+++), 75.1–90% as 0.5 (++), 50–75% as 0.25 (+) and less than 50% as 0 (-). …”