<i>In Vivo</i> Substrates of the Lens Molecular Chaperones αA-Crystallin and αB-Crystallin by Usha P. Andley (354477)

“…The amount of degraded glutamate dehydrogenase, α-enolase, and cytochrome c increased more than 50-fold in homozygous αA-R49C mutant lenses. In αB-R120G mouse lenses, our analyses identified decreased abundance of phosphoglycerate mutase, several β- and γ-crystallins, and degradation of αA- and αB-crystallin early in cataract development. …”

Data_Sheet_1_Middle Cerebellar Peduncle Width—A Novel MRI Biomarker for FXTAS?.PDF by Annie L. Shelton (5445332)

“…<p>Fragile X-associated tremor/ataxia syndrome (FXTAS) is a severe neurodegenerative movement disorder affecting over 40% of male and 16% of female FMR1 premutation carriers over the age of 50. …”

Ca²⁺ signalling and mitochondrial physiology defects in cells lacking anxA6. by Marcin Chlystun (288876)

“…(C) ΔΨm in <i>AnxA6</i>^+/+ and <i>AnxA6</i>^−/− ear fibroblasts was measured in cells equilibrated with 50 nM TMRM under resting conditions. …”

Sensitivity of various GFP insertion constructs (<i>columns A through J</i>) to protein misfolding. by Stéphanie Cabantous (92574)

“…<p>(A) Images of <i>E. coli</i> cells on plates expressing four test fusions proteins with decreasing folding robustness at 37°C. …”

Impaired bone formation in <i>Col1a1-Krm2</i> transgenic mice. by Jochen Schulze (365258)

“…<p>(A) Toluidine blue staining of non-decalcified vertebral body sections from 6 weeks old female wildtype and <i>Col1a1-Krm2</i> transgenic littermates revealing that the normal appearance of cuboidal osteoblasts (arrows) covering trabecular bone surfaces is only observed in wildtype controls (scale bars, 50 µm). …”

Dynamic profiles of the prototypic integrated system under different conditions, and a comparison to the kinetic-based model. by Jong Min Lee (271984)

“…<p>The concentration of carbon and amount of biomass within the cellular system over a simulation time of 10 h is illustrated. The decreasing lines represent the concentration of carbon (as indicated by the left <i>y</i>-axis), which is being consumed, in the system. …”

The impact of improved detection and treatment of isoniazid resistant tuberculosis on prevalence of multi-drug resistant tuberculosis: A modelling study by Kamila Romanowski (6260870)

“…</p><p>Conclusion</p><p>Accurate diagnosis and tailored treatment of INHR-TB with LPA led to an almost 50% relative decrease in acquired MDR-TB when compared with an Xpert MTB/RIF strategy. …”

dAβ expression alters memory only when associated with APPL partial loss-of-function. by Isabelle Bourdet (783402)

DataSheet_1_Investigating miR-9 as a mediator in laryngeal cancer health disparities.docx by Christina Gobin (15181795)

“…In this study, we present our computational analysis of differentially expressed miRNAs in Black compared with White laryngeal cancer and further validate microRNA-9-5p (miR-9-5p) as a potential mediator of cancer phenotype and chemoresistance.…”

Increased sediment load during a large-scale dam removal changes nearshore subtidal communities by Stephen P. Rubin (4672648)

“…Macroalgae, predominantly kelp and foliose red algae, were abundant before dam removal with combined cover levels greater than 50%. Where persistent sediment deposits formed, macroalgae decreased greatly or were eliminated. …”

DataSheet1_A novel hybrid bioprocess strategy addressing key challenges of advanced biomanufacturing.PDF by Lucas Nik Reger (14632742)

“…In addition, we could demonstrate scalability of the process to a 5L benchtop system, using a fluidized-bed centrifuge as scalable media exchange system. …”

A mutation in the <i>CACNA1C</i> gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study by Xin Liu (43569)

“…</p><p>Methods and results</p><p>We described a large Chinese family with nocturnal sudden cardiac death induced by ERS in most of the young male adults. …”

<i>Operando</i> Particle-Scale Characterization of Silicon Anode Degradation during Cycling by Ultrahigh-Resolution X‑ray Microscopy and Computed Tomography by Paul Choi (1762975)

“…At low rate cycling, the X-ray signal attenuation over the Si particles decreased with increased lithiation. In contrast, at high rate cycling, we observe increased attenuation at the electrode scale. …”

<i>Operando</i> Particle-Scale Characterization of Silicon Anode Degradation during Cycling by Ultrahigh-Resolution X‑ray Microscopy and Computed Tomography by Paul Choi (1762975)

“…At low rate cycling, the X-ray signal attenuation over the Si particles decreased with increased lithiation. In contrast, at high rate cycling, we observe increased attenuation at the electrode scale. …”

<i>Operando</i> Particle-Scale Characterization of Silicon Anode Degradation during Cycling by Ultrahigh-Resolution X‑ray Microscopy and Computed Tomography by Paul Choi (1762975)

“…At low rate cycling, the X-ray signal attenuation over the Si particles decreased with increased lithiation. In contrast, at high rate cycling, we observe increased attenuation at the electrode scale. …”

Data from: Large subsurface carbon stocks in a long-term no-tillage site are vulnerable to potential mineralization by Qiuping Peng (20147290)

“…Soil cores were sampled to 153 cm depth at 25 locations representing 5 distinct soil series, a range in landscape positions, and a range in profile organic carbon contents. …”

Inspiratory muscle training is effective to reduce postoperative pulmonary complications and length of hospital stay: a systematic review and meta-analysis by Filipa Kendall (3642886)

“…IMT significantly reduced the risk of PPC (Risk Ratio (RR) = 0.50, 95%CI: 0.39, 0.64, <i>I²</i>=<i></i>0.0%), and a decrease in LOS (Mean Difference = −1.41, 95%CI: −2.07, −0.75, <i>I</i>² = 0.0%).…”

Deletion of <i>Wt1</i> during early gonadogenesis has a great impact on ovarian morphogenesis. by Alejo Torres-Cano (12878169)

“…Decreased CDH1 and RALDH2 expression was observed in the OE of <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> P5 mice. …”

Data_Sheet_1_Sense of agency at a gaze-contingent display with jittery temporal delay.docx by Junhui Kim (18575083)

“…We manipulated the delay between eye movements and display updates using a truncated normal distribution (μ to μ + 2 σ) with μ ranging from 0 to 400 ms and σ fixed at 50 ms. …”

Dynamin inhibition by dynasore affects LTP, a type of synaptic plasticity due to sustained activity in hippocampus. by Mauro Fà (59065)

“…<p><b>A</b>, Dynasore (80 μM, 20 minute perfusion, open triangles) decreases LTP induced by theta-burst stimulation in CA₃–CA₁ synapses compared to vehicle-treated slices (black circles)(F_1,10 = 9.081, <i>p</i> = 0.013). …”