Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

“…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Low-dose <b>35m</b> remarkably decreases LPS-induced IL-1β release both <i>in vitro</i> and <i>in vivo</i> by blocking the activation of NLRP3, indicating that <b>35m</b> can be a potential orally active therapeutic agent for the treatment of NLRP3-related diseases.…”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Low-dose <b>35m</b> remarkably decreases LPS-induced IL-1β release both <i>in vitro</i> and <i>in vivo</i> by blocking the activation of NLRP3, indicating that <b>35m</b> can be a potential orally active therapeutic agent for the treatment of NLRP3-related diseases.…”

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…To develop more potent compounds, we initiated a structure–activity relationship study that identified 2-aminobenzoxazole as a viable scaffold. …”

Fig 3 - by Yan Shu (441370)

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD₅₀ = 8.4 μM, p ≤ 0.05). …”

Pulse Ultrasound-Based Response Enhancement of a MOX Gas Sensor by Yumin Yang (5737235)

“…For 2 ppm methanol, the RE by the pulse ultrasound is 50%, relative to the continuous ultrasound, when the pulse width, duty ratio, and working frequency are 0.4 ms, 50%, and 110.1 kHz, respectively. …”

Pulse Ultrasound-Based Response Enhancement of a MOX Gas Sensor by Yumin Yang (5737235)

“…For 2 ppm methanol, the RE by the pulse ultrasound is 50%, relative to the continuous ultrasound, when the pulse width, duty ratio, and working frequency are 0.4 ms, 50%, and 110.1 kHz, respectively. …”

Histology of the perfused intestinal tract at the end of the 3 hours of extracorporeal circulation (H&E stain, 100x, scale bar = 200 μm). by Matteo Dell’Anno (10724418)

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Proliferation of intestinal crypt epithelial cells. by Matteo Dell’Anno (10724418)

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Diet composition and nutritional values. by Taynara Aparecida Vieira (16401726)

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Nutritional and metabolic analysis. by Taynara Aparecida Vieira (16401726)

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Cardiovascular parameters. by Taynara Aparecida Vieira (16401726)

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Mineral concentrations measured over time in blood plasma and intestinal lumen content. by Matteo Dell’Anno (10724418)

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Cardiac inflammatory parameters. by Taynara Aparecida Vieira (16401726)

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Mean fecal egg count per individual before and after administration of a single oral dose albendazole. by Martin Walker (170282)

Influence of Interfacial Gas Enrichment on Controlled Coalescence of Oil Droplets in Water in Microfluidics by Jianlong Wang (438075)

“…When the amount of dissolved gases (oxygen) in oil decreases (from 7.89 to 4.59 mg/L), the average drainage time of coalescence significantly increases (from 19 to 50 ms). …”

Effect of <i>bipA</i> deletion on biofilm formation in <i>E. coli</i> and <i>S</i>. Typhimurium. by Eunsil Choi (8271039)

<i>Bbs1</i>^{<i>M390R/M390R</i>} mice have decreased hippocampal proliferation. by Thomas K. Pak (10686881)

“…At P30, mice were started on BrdU injections (2x50mg/kg) for five days. At P44, mice were taken down. …”