Congener Variation of Genetic Dependent-Developmental Toxicology in Two Emerging Classes of Dioxin-like Compounds by Yishan Lin (9159326)

“…Emerging classes of dioxin-like compounds (DLCs) like hydroxylated/methoxylated polybrominated diphenyl ethers (HO-/MeO-PBDEs) and polychlorinated diphenyl sulfides (PCDPSs) could lead to diverse adverse outcomes in humans and wildlife, yet knowledge gaps exist in their molecular mechanisms associated with different structures following early life environmental exposure. This study integrated a genetic knockout technique and concentration-dependent reduced zebrafish transcriptome approach (CRZT) to unravel the toxicological pathways underpinning developmental toxicity of four HO-/MeO-PBDEs and five PCDPSs at environmentally relevant doses. …”

Trypacidin, a Spore-Borne Toxin from <em>Aspergillus fumigatus</em>, Is Cytotoxic to Lung Cells by Thierry Gauthier (185229)

“…We found that spores of <em>A. fumigatus</em> contain five main compounds, tryptoquivaline F, fumiquinazoline C, questin, monomethylsulochrin and trypacidin. …”

HNRNPD regulates the biogenesis of circRNAs and the ratio of mRNAs to circRNAs for a set of genes by Shuhui Chang (19479069)

Effect of corticosteroids over plantar fascia thickness in plantar fasciitis: a systematic review and meta-analysis by Víctor M. Peña-Martínez (16324399)

Data_Sheet_2_A meta-review of standard polysomnography parameters in Rett Syndrome.pdf by Xin-Yan Zhang (3541766)

“…Findings of comparison with literature normative values suggested shorter total sleep time (TST) and sleep onset latency (SOL), twice as long wake after sleep onset (WASO) with lower sleep efficiency (SEI) in RTT, as well as increased non-rapid eye movement stage 3 (stage N3) and decreased rapid eye movement sleep. Based on limited data per stratifications, we found in RTT cases <5 years old lower stage N3, and in RTT cases >5 years old less WASO and more WASO in the epileptic strata. …”

Data_Sheet_3_A meta-review of standard polysomnography parameters in Rett Syndrome.docx by Xin-Yan Zhang (3541766)

“…Findings of comparison with literature normative values suggested shorter total sleep time (TST) and sleep onset latency (SOL), twice as long wake after sleep onset (WASO) with lower sleep efficiency (SEI) in RTT, as well as increased non-rapid eye movement stage 3 (stage N3) and decreased rapid eye movement sleep. Based on limited data per stratifications, we found in RTT cases <5 years old lower stage N3, and in RTT cases >5 years old less WASO and more WASO in the epileptic strata. …”

Data_Sheet_1_A meta-review of standard polysomnography parameters in Rett Syndrome.docx by Xin-Yan Zhang (3541766)

“…Findings of comparison with literature normative values suggested shorter total sleep time (TST) and sleep onset latency (SOL), twice as long wake after sleep onset (WASO) with lower sleep efficiency (SEI) in RTT, as well as increased non-rapid eye movement stage 3 (stage N3) and decreased rapid eye movement sleep. Based on limited data per stratifications, we found in RTT cases <5 years old lower stage N3, and in RTT cases >5 years old less WASO and more WASO in the epileptic strata. …”

Impacts of crop rotational diversity and grazing under integrated crop-livestock system on soil surface greenhouse gas fluxes by Gandura Omar Abagandura (6725744)

“…The cropping system investigated here included spring wheat grown continuously for five years and a 5-yr crop rotation (spring wheat-cover crops-corn-pea/barley-sunflower). …”

Immunofluorescent staining of TMEM43 and IC disc proteins in HL-1 cells stably expressing wild-type and mutant TMEM43. by Vinayakumar Siragam (455948)

Assessment of metabolic alterations in Leishmania-infected bone marrow-derived macrophages. by Elaine Carvalho de Oliveira (11630455)

Validation of ING3 in combination with AZD5582 as a HIV-1 latency maintenance factor. by Emily Hsieh (377992)

“…<p><b>(A)</b> HIV-1 reverse transcriptase activity (y-axis) of the viral supernatant of NTC sgRNA transduction or <i>ING3</i> knockout in J-Lat 10.6 and 5A8 treated with 10 nM AZD5582 or an equivalent volume of DMSO. …”

Data_Sheet_1_The Aha! experience is associated with a drop in the perceived difficulty of the problem.docx by Nadezhda V. Moroshkina (12904751)

“…To test our hypotheses, we developed a novel set of rebus puzzles. A total of 160 participants solved rebuses and provided initial (within 5 s of problem presentation) and retrospective difficulty ratings (following the generation or presentation of a correct solution). …”

The efficacy of topical 8% capsaicin patches for the treatment of postsurgical neuropathic pain: a systematic review by Brandon Goodwin (20328988)

“…Five commonly used databases were employed utilizing a search string made from MeSH terms and boolean operators. …”

Assessment of physiological and electrochemical effects of a repurposed Zinc dithiocarbamate complex on Acinetobacter baumannii biofilms by Obinna Ajunwa (12530125)

“…Among the DTC-metal complexes and DTCs tested, ZnL1 (N-methyl-1-phenyldithiocarbamato-S,S’ Zn(II)), originally designed as an antitumor agent, is effective against biofilm forming <em>A. baumannii.</em> A MIC value of 12.5 µM, comparable to that of Gentamicin (5 µM) was measured for planktonic cells in tryptic soy broth. …”

Role of α1^ins in spinal nociceptive modification. by Zi-Yang Zhang (4988555)

“…<i>n</i> = 21 slices from 5 mice. Scale bar: 5 μm. (<b>C</b>) GlyR-mIPSC amplitudes were decreased at day 28 after intraspinal injection of AAV encoding shRNA-α1^ins. …”

Description of the study population. by Jane Kabami (310926)

“…</p><p>Methods</p><p>We conducted a time series analysis using data from a dynamic cohort of persons with HIV enrolled between March 2017 and September 2021 at HIV clinics in Masaka and Mbarara Regional Referral Hospitals in Southwestern Uganda. …”

S1 File - by Jane Kabami (310926)

“…</p><p>Methods</p><p>We conducted a time series analysis using data from a dynamic cohort of persons with HIV enrolled between March 2017 and September 2021 at HIV clinics in Masaka and Mbarara Regional Referral Hospitals in Southwestern Uganda. …”

Supplementar Material for: Population-Genetic Influences on Genomic Estimates of the Inbreeding Coefficient: A Global Perspective by Pemberton T.J. (3831982)

“…For the small number of populations with specific consanguinity estimates, we find a correlation between inbreeding coefficients and consanguinity frequency (<i>r</i> = 0.349, p = 0.040). …”

A<i>ß</i> stimulation of platelets induces ROS generation and cell membrane scrambling. by Nina S. Gowert (528687)

“…(G) Bar graphs depict mean values ±SEM (n = 5, left panel) of the percentage of human platelets binding Annexin V-Fluos after pre-treatment with caspase inhibitor 1 µM zVAD-FMK (zVAD) followed by a 60 min. exposure with 20 ng/ml A<i>ß</i> in the presence of 2 mM CaCl₂ and in the nominal absence of Ca²⁺ and presence of EGTA, **p<0.01 indicates statistically significant difference to the control in the absence of Aß, *p<0.05 indicates statistically significant difference to results with 20 ng/ml A<i>ß</i> alone in the absence of any pre-treatment. …”

Phase contrast images of MCF7 cells. by Fazal Khan (3149331)

“…<p>Phase contrast images of MCF7 cells showing morphological changes in a dose and time-dependent manner following treatment with MEAD at 5, 10, 15, 20 and 25 mg/ml. …”