Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects by Xiaopeng Peng (9136955)

“…Importantly, the combination of <b>NT-6</b> with a small-molecule PD-L1 inhibitor NP-19 decreased tumor burden significantly (TGI% = 77.6%). …”

Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects by Xiaopeng Peng (9136955)

“…Importantly, the combination of <b>NT-6</b> with a small-molecule PD-L1 inhibitor NP-19 decreased tumor burden significantly (TGI% = 77.6%). …”

Effect of the W501R substitution on the ability of HCV helicase to unwind DNA. by Paola J. S. Provazzi (835454)

“…The reactions were prepared containing 25 mM MOPS, 1.25 mM MgCl₂, 5 nM Cy5-substrate; 1mM ATP, 0.05 mM DTT, 0.005 mg/mL BSA, 0.001% Tween20, and enzymes NS3h_1b (con1), NS3h_3a (wt) and NS3h_3a (W501R) at indicated concentrations.…”

Temporal Trends of Great Lakes Legacy Contaminants: Ecological and Biological Considerations Applying the Age-Trend Model by James J. Pagano (2043490)

“…Our research revealed that select legacy contaminant groups (∑PCBs, ∑DDTs, ∑chlordanes, and ∑5PBDEs) have similar <i>t</i>_1/2 and <i>k</i>₂ values across the Great Lakes, with the exception of both Lake Erie sites and the Lake SuperiorKeweenaw Point site. …”

Calculated cytoplasmic conductivities over [Na⁺] of suspending solutions at two desired temperatures. by Chadapust J. Sudsiri (14670602)

Integration of CcnA in the cell cycle regulation model in <i>C</i>. <i>crescentus</i>. by Wanassa Beroual (5314028)

“…<p><b>(A)</b> Secondary structure prediction of 5′ UTR of <i>ctrA</i> starting from the TSS of <i>ctrA-</i>P2 using « The DINAmelt Web server » –Two-state melting (folding) with default parameters for RNA energy rules [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001528#pbio.3001528.ref065" target="_blank">65</a>]. …”

Comparisons of normalized reads of indicated classes of small RNAs in <i>lin-35(n745)</i> with wild type. by Ashwin Seetharaman (615458)

“…The rest of the small RNAs are represented as light gray data points. Lines denoting equal, 5-fold increased and 5-fold decreased expression are shown as light gray dashed lines. …”

Comparisons of normalized reads of indicated classes of small RNAs in <i>lin-15b(n744)</i> with wild type. by Ashwin Seetharaman (615458)

“…The rest of the small RNAs are represented as light gray data points. Lines denoting equal, 5-fold increased and 5-fold decreased expression are shown as light gray dashed lines. …”

Comparisons of normalized reads of indicated classes of small RNAs in <i>lin-35(n745); glp-4(bn2)</i> with <i>glp-4(bn2)</i>. by Ashwin Seetharaman (615458)

“…The rest of the small RNAs are represented as light gray data points. Lines denoting equal, 5-fold increased, and 5-fold decreased expression are shown as light gray dashed lines. …”

Comparisons of normalized reads of indicated classes of small RNAs in <i>lin-52(n771)</i> with wild type. by Ashwin Seetharaman (615458)

“…The rest of the small RNAs are represented as light gray data points. Lines denoting equal, 5-fold increased and 5-fold decreased expression are shown as light gray dashed lines. …”

Comparisons of normalized reads of indicated classes of small RNAs in <i>lin-9(n112)</i> with wild type. by Ashwin Seetharaman (615458)

“…The rest of the small RNAs are represented as light gray data points. Lines denoting equal, 5-fold increased and 5-fold decreased expression are shown as light gray dashed lines. …”

GLAST-Cre⁺ cells from the GER mitotically regenerate IPhCs. by Tomokatsu Udagawa (11675636)

“…<p>Representative images of apical turns are shown. (A, C) Cryosections of P4 and P7 control cochleae with Fabp7⁺ Sox2⁺ IPhCs (arrowheads). …”

Impact of Appropriate Antimicrobial Therapy for Patients with Severe Sepsis and Septic Shock – A Quality Improvement Study by Paula K. O. Yokota (655314)

Arrested Catalysis: Controlling Kumada Coupling Activity via a Redox-Active N-Heterocyclic Carbene by Andrew G. Tennyson (1419994)

“…Addition of 2 equiv of cobaltocene (with respect to <b>3a</b>) to the coupling reaction with bromotoluene caused a decrease in catalytic activity (from 4.7 × 10⁻⁵ to 2.7 × 10⁻⁶ s⁻¹), which was attributed to the conversion of <b>3a</b> to an arrested state. …”

Arrested Catalysis: Controlling Kumada Coupling Activity via a Redox-Active N-Heterocyclic Carbene by Andrew G. Tennyson (1419994)

“…Addition of 2 equiv of cobaltocene (with respect to <b>3a</b>) to the coupling reaction with bromotoluene caused a decrease in catalytic activity (from 4.7 × 10⁻⁵ to 2.7 × 10⁻⁶ s⁻¹), which was attributed to the conversion of <b>3a</b> to an arrested state. …”

Arrested Catalysis: Controlling Kumada Coupling Activity via a Redox-Active N-Heterocyclic Carbene by Andrew G. Tennyson (1419994)

“…Addition of 2 equiv of cobaltocene (with respect to <b>3a</b>) to the coupling reaction with bromotoluene caused a decrease in catalytic activity (from 4.7 × 10⁻⁵ to 2.7 × 10⁻⁶ s⁻¹), which was attributed to the conversion of <b>3a</b> to an arrested state. …”

Simple Scalable Fabrication of Laser-Induced Graphene Composite Membranes for Water Treatment by Abhishek Gupta (402938)

“…An enhanced removal of bacteria was observed at 2.5 V during filtration. This work demonstrates a method to scale up LIG composite membranes, a crucial step that is necessary in determining their commercial potential in water technology applications.…”

Simple Scalable Fabrication of Laser-Induced Graphene Composite Membranes for Water Treatment by Abhishek Gupta (402938)

“…An enhanced removal of bacteria was observed at 2.5 V during filtration. This work demonstrates a method to scale up LIG composite membranes, a crucial step that is necessary in determining their commercial potential in water technology applications.…”

Fig 1 - by Valérie Chetboul (579758)

Effect of ibuprofen (IBU) on carbonic anhydrase IX (CA IX) expression. by Katarina Grossmannova (7543517)

“…<p>HCT116, RKO, FaDu and UM-22A cells cultured in monolayers in hypoxic conditions (1% O2) were lyzed at 24h and 48h of treatment with 0.5 mM IBU, 1 mM IBU, or DMSO as control (0 mM). …”