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5.HT<sub>1A</sub> binding difference between known cause of death (KCOD) controls and SIDS.
Published 2025“…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT<sub>1A</sub> receptor binding. Data include the combined South Africa and Northern Plains cohorts.…”
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Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf
Published 2022“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …”
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Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf
Published 2022“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …”
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Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf
Published 2022“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …”
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HC11 cells increase Pthlh gene expression and activity via cAMP with increases in intracellular 5HT.
Published 2020“…<p><b>A-C.</b> 5HTP significantly increases intracellular 5HT at 12- and 72 hours post treatment compared to baseline and at 12 hours compared to lactogenic control <b>(B).…”
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Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [<sup>18</sup>F]ENL30: A Potential PET Radiotracer for the 5‑HT<sub>7</sub> Receptor
Published 2019“…However, we believe that [<sup>18</sup>F]ENL30 may prove to be valuable in higher species that exhibit decreased <i>P</i>-gp dependency. If required, σ-receptor binding could, in such studies, be selectively blocked potentially allowing for selective 5-HT<sub>7</sub>R imaging.…”
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Table_1_Gender-Specific Effect of 5-HT and 5-HIAA on Threshold Level of Behavioral Symptoms and Sex-Bias in Prevalence of Autism Spectrum Disorder.DOCX
Published 2020“…Age did not influence the neurochemical parameters, but imitation, listening responses and nonverbal communication scores decreased with age. Conversely in female probands, plasma 5-HIAA level significantly attenuated with age, when platelet 5-HT content remained unchanged. …”
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Image 5_Using sodium glycodeoxycholate to develop a temporary infant-like gut barrier model, in vitro.pdf
Published 2025“…</p>Methods<p>This study aimed to develop an in vitro model of the infant gut barrier treating Caco-2/HT29-MTX with 0.5, 0.8, and 1 mM sodium glycodeoxycholate (GDC).…”
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Table_1_Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling.DOCX
Published 2020“…Background<p>Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. …”