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ppm decrease » _ decrease (Expand Search), a decrease (Expand Search), pa decreased (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
nm decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
ht decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
10 nm » 100 nm (Expand Search), 10 mm (Expand Search)
5 ht » 5 h (Expand Search)
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Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction.
Published 2019“…(F) Decreasing levels of RID neural activity during the transition periods from forward to backward locomotion in mock, 5-HT pre-exposed (p = 1.3 × 10<sup>−3</sup>), and <i>mod-1</i> mutant (p = 5.4 × 10<sup>−4</sup>) animals. …”
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5-HT inhibits <i>P</i>. <i>berghei</i> infection in mosquitoes.
Published 2024“…(J) Oocyst numbers in control (Ctrl, <i>n</i> = 62) and mosquitoes orally supplemented with 10 nM (<i>n</i> = 43), 100 nM (<i>n</i> = 47) and 1000 nM (<i>n</i> = 64) 5-HT. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis
Published 2025“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis
Published 2025“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries
Published 2023“…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …”
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Evidence of Formation of 1–10 nm Diameter Ice Nanotubes in Double-Walled Carbon Nanotube Capillaries
Published 2023“…However, the single-walled INTs reported in the literature all possess subnanometer diameters (<1 nm). Herein, based on systematic and large-scale molecular dynamics simulations, we demonstrate the spontaneous freezing transition of liquid water to single-walled INTs with diameters reaching ∼10 nm when confined to capillaries of double-walled carbon nanotubes (DW-CNTs). …”