Image_4_The Valproate Mediates Radio-Bidirectional Regulation Through RFWD3-Dependent Ubiquitination on Rad51.tif by Guochao Liu (10450499)

“…Here, using the 7,12-dimethylbenz[α]anthracene (DMBA)-induced malignant transformed MCF10A cells, we found that valproate (VPA), a histone deacetylase inhibitor (HDACi), radiosensitized transformed cells while alleviated IR-induced damage in normal cells at a safe dose (0.5 mM). …”

Image3_Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells.TIF by William Bachman (12459624)

“…Increases (≥two-fold) were also observed in levels of Wnt signaling regulator (glypican-4), actin-binding chromatin modulator (BRG1) and nuclear actin filament depolymerizing protein (MICAL2; microtubule-associated monooxygenase, calponin and LIM domain containing), together with a decrease in tissue plasminogen activator. These changes were independently further confirmed by immunoblotting analysis. …”

Data_Sheet_3_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.ZIP by Kalyan C. Vinnakota (43374)

“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”

DataSheet_2_Natal environmental conditions modulate senescence of antler length in roe deer.csv by Solène Cambreling (16493826)

“…We found evidence of similar patterns of antler length senescence in both populations, with an onset of senescence around 7 years of age and a decrease of length by about 1–1.5 cm per additional year of life from 7 years of age onwards. …”

Table_1_PUB11-Dependent Ubiquitination of the Phospholipid Flippase ALA10 Modifies ALA10 Localization and Affects the Pool of Linolenic Phosphatidylcholine.xlsx by Juliette Salvaing (62574)

“…In Arabidopsis, ALA10, a phospholipid flippase of the P₄ type-ATPase family, counteracts the limitation of monogalactosyldiacylglycerol (MGDG) production and has a positive effect on leaf development. …”

Neutral Gold Complexes with Tridentate <i>SNS</i> Thiosemicarbazide Ligands by Pedro I. da S. Maia (2117377)

“…On the other hand, the reduction of Au^III to Au^I leads to a considerable decrease of the cytotoxicity.…”

Induction of apoptosis by pinostrobin in human cervical cancer cells: Possible mechanism of action by Alka Jaudan (4839792)

“…Additionally, a significant increase in the expression of proteins of extrinsic (TRAIL R1/DR4, TRAIL R2/DR5, TNF RI/TNFRSF1A, FADD, Fas/TNFRSF6) and intrinsic pathway (Bad, Bax, HTRA2/Omi, SMAC/Diablo, cytochrome C, Pro-Caspase-3, Cleaved Caspase-3) was observed in the cells exposed to P_N. …”

Image_2_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.tif by Kalyan C. Vinnakota (43374)

“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”

Table_3_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc by Sofia Priyadarsani Das (17830028)

“…The diet containing L. acidophilus at 1 × 10⁷ CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. …”

Image4_Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells.TIF by William Bachman (12459624)

“…Increases (≥two-fold) were also observed in levels of Wnt signaling regulator (glypican-4), actin-binding chromatin modulator (BRG1) and nuclear actin filament depolymerizing protein (MICAL2; microtubule-associated monooxygenase, calponin and LIM domain containing), together with a decrease in tissue plasminogen activator. These changes were independently further confirmed by immunoblotting analysis. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Supplementary Material for: Population-Attributable Risk Fractions for Antiplatelets and Anticoagulants in Spontaneous Intracranial Hemorrhages by Choi H.H. (14759125)

“…<b><i>Methods:</i></b> From the National Health Insurance Service-National Sample Cohort including 1,108,369 citizens, 4,385 cases, aged 20 years or more and newly diagnosed as sICHs between 2003 and 2015, were included in this study. A total of 65,775 sICH-free controls were randomly selected at a ratio of 1:15 from individuals with the same birth year and sex according to a nested case-control study design. …”

The structure of spontaneous locomotion in zebrafish larvae and mice during the active phase of the circadian cycle (light for zebrafish larvae, dark for mice). by Stefan Spulber (148803)

“…Zebrafish larvae exposed to 1 mg/L PFOS have a hyperactive phenotype characterized by a 2.5 fold higher distance swum during spontaneous bouts of activity. …”

Large-Scale Spatio-Temporal Patterns of Mediterranean Cephalopod Diversity by Stefanie Keller (220749)

“…While the western basin showed a high diversity, our analyses do not support a steady eastward decrease of diversity as proposed in some previous studies. …”

Table_2_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.XLSX by Kalyan C. Vinnakota (43374)

“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”

Metformin treatment inhibited the expression of 4EBP1 and S6K1. by Feng Wang (44414)

“…<p><b>A</b>. KYSE 450 cells were treated with 5, 10, 20 mmol/L of metformin for 48h. …”

Grüter et al. (2022) PLOS ONE "Expected global suitability..." by Roman Grüter (10679589)

“…Per crop, four raster maps (.tif raster format) are available:</div><div>The crops' overall current suitability (crop_current.tif), the current climate suitability (crop_climate.tif) based on climate parameters only, the current land and soil suitability (crop_soil.tif) based on land and soil parameters only and the suitability change by 2050 due to climate change according to RCP4.5.</div><div>For the former three maps (crop_current.tif, crop_climate.tif, crop_soil.tif), each raster cell contains a value between 1 to 4 which represent decreasing crop suitability (1: S1 very suitable; 2: S2 moderately suitable; 3: S3 marginally suitable; 4: N unsuitable).…”

Heat map grid summarizing the effects of LPS and BET inhibitors on target gene mRNA expression in DSCs. by Sandeep Ajgaonkar (14774336)

“…The significance threshold is 5% FDR (Q<0.05), highlighted in bold. The orange color indicates a significant increase, the blue color indicates a significant decrease regarding the contrasts shown. …”

DataSheet_1_Natal environmental conditions modulate senescence of antler length in roe deer.csv by Solène Cambreling (16493826)

“…We found evidence of similar patterns of antler length senescence in both populations, with an onset of senescence around 7 years of age and a decrease of length by about 1–1.5 cm per additional year of life from 7 years of age onwards. …”

Sensitivity of retinal endothelial cells by FP59 and LeTx <i>in vitro</i> and <i>in vivo</i>. by Jennifer L. Bromberg-White (259780)

“…Immunoblots indicate cleavage of MEK1 following LeTx treatment via loss of N-terminal epitope (MEK1 NT), as well as a decrease in phosphorylated ERK (pERK). (D) <i>In vivo</i> analysis of retinal vasculature following intravitreal injection of FP59 and PA (0.02 µg FP59 and 0.1 µg PA in 1 µL) of postnatal day 10 (PN10) and PN21 C57BL/6 mice. …”