2020 Boston qualifying times. by Laura Albrecht (1792711)

“…Currently, women’s qualifying times in each age group are thirty minutes slower than the men’s qualifying times equating to a 16.7% adjustment for the 18-34 age group, decreasing with age to a 10.4% adjustment for the 80+ age group. …”

Immunomodulation by gastrointestinal carbon black nanoparticle exposure in ovalbumin T cell receptor transgenic mice by Jason H. Fine (3109035)

Table_1_Accessibility to Non-COVID Health Services in the World During the COVID-19 Pandemic: Review.docx by Magdalena Tuczyńska (11842118)

“…Methods used in the studies were based on retrospective analysis or on the subjective assessment of patients in the form of a questionnaire or interview. Most authors claimed a decrease in accessibility to health services during the COVID-19 pandemic compared to the pre-pandemic period, including a decrease in planned surgeries, doctor appointments, patient admission to hospital or ER, and access to medicines. …”

Table_3_Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis.DOCX by Qiang Lu (49688)

“…Patients with pre-existing meibomian gland dysfunction (MGD) had worsened subjective symptoms of dry eye (1.31, 95% confidence interval (CI) [0.66, 1.95], P < 0.0001), a reduced tear break-up time (BUT) (−2.27, 95% CI [−2.66, −1.88], P < 0.0001), and a worse corneal fluorescein staining (CFS) score (0.75, 95% CI [0.5, 1.0], P < 0.0001) after phacoemulsification cataract surgery, whereas in the general population, the subjective symptoms score and CFS remained unchanged and BUT decreased slightly after surgery. …”

Table_1_Body Mass Index, Diabetes, and Risk of Tuberculosis: A Retrospective Cohort Study.PDF by Hayoung Choi (3279576)

“…However, compared to the normal weight without DM, the severely obese without DM and those with DM showed a 0.37 (95% CI, 0.36–0.38) and a 0.42 (95% CI, 0.36–0.48)-fold decreased risk of TB, respectively. …”

Image_1_Microplastics influence the functional responses of a tropical estuarine calanoid Pseudodiaptomus annandalei.tif by Jaigopal Sharma (17901740)

“…Considered three types of functional response: (i) with increasing food density, when intake rate increases linearly until asymptote, called Type-I functional response; (ii) when the proportion of prey ingested by the consumer decreases monotonically with prey density, considered as a Type-II functional response; and (iii) when ingestion rate and food density show a sigmoid relationship, is considered as Type-III functional response. …”

Molecular Basis for Vulnerability to Mitochondrial and Oxidative Stress in a Neuroendocrine CRI-G1 Cell Line by Natasha Chandiramani (233718)

“…Genome-wide gene expression analysis and follow-up biochemical studies revealed that, in this experimental system, increased vulnerability to mitochondrial and oxidative stress was associated with (1) inhibition of ARE/Nrf2/Keap1 antioxidant pathway; (2) decreased expression of antioxidant and phase I/II conjugation enzymes, most of which are Nrf2 transcriptional targets; (3) increased expression of molecular chaperones, many of which are also considered Nrf2 transcriptional targets; (4) increased expression of β cell-specific genes and transcription factors that specify/maintain β cell fate; and (5) reconstitution of glucose-stimulated insulin secretion.…”

Organ burden of inhaled nanoceria in a 2-year low-dose exposure study: dump or depot? by Jutta Tentschert (1277127)

“…The CeO₂ burden for lung, lung-associated lymph nodes, and major non-pulmonary organs, blood, and feces, was determined in a chronic whole-body inhalation study in female Wistar rats undertaken according to OECD TG453 (6 h per day for 5 days per week for a 104 weeks with the following concentrations: 0, 0.1, 0.3, 1.0, and 3.0 mg/m³, animals were sacrificed after 3, 12, 24 months). …”

Polymorphisms of microRNA Sequences or Binding Sites and Lung Cancer: A Meta-Analysis and Systematic Review by Zhiwei Chen (254191)

“…Methodological quality of eligible studies was adequate with an average score of 8.5. miRNA-196a2 rs11614913 polymorphism was associated with increased lung cancer risk (homozygote comparison, OR = 1.299, 95% CI: 1.096–1.540; dominant model, OR = 1.217, 95% CI: 1.041–1.421) and decreased survival. …”

Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study by Susan Martin (6648740)

“…MR analysis provided evidence only for a causal role of liver fat and pancreas volume on risk of type 2 diabetes (1.27 [1.08,1.49] or 27% increased risk and 0.76 [0.62,0.94] or 24% decreased risk per 1SD, respectively) and no causal associations with type 1 diabetes.…”

Image_1_Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis.TIF by Qiang Lu (49688)

“…Patients with pre-existing meibomian gland dysfunction (MGD) had worsened subjective symptoms of dry eye (1.31, 95% confidence interval (CI) [0.66, 1.95], P < 0.0001), a reduced tear break-up time (BUT) (−2.27, 95% CI [−2.66, −1.88], P < 0.0001), and a worse corneal fluorescein staining (CFS) score (0.75, 95% CI [0.5, 1.0], P < 0.0001) after phacoemulsification cataract surgery, whereas in the general population, the subjective symptoms score and CFS remained unchanged and BUT decreased slightly after surgery. …”

Image_1_Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.tif by Chien-Ming Lin (740034)

“…</p>Objective<p>A 45-year-old male presenting with moderate hypercalcemia, hypocalciuria, and inappropriately high parathyroid hormone (PTH) had a good response to cinacalcet (total serum calcium (Ca²⁺) from 12.5 to 10.1 mg/dl). …”

Table_2_Retinal microvasculature features in patients with migraine: a systematic review and meta-analysis.XLSX by Yulian Pang (14002071)

“…Background<p>Migraine is a central nervous system disorder involving neuronal and vascular factors. …”

Image_2_Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.tif by Chien-Ming Lin (740034)

“…</p>Objective<p>A 45-year-old male presenting with moderate hypercalcemia, hypocalciuria, and inappropriately high parathyroid hormone (PTH) had a good response to cinacalcet (total serum calcium (Ca²⁺) from 12.5 to 10.1 mg/dl). …”

Taxes on Sugar-Sweetened Beverages to Reduce Overweight and Obesity in Middle-Income Countries: A Systematic Review by Sharon S. Nakhimovsky (3138477)

“…Estimates for own-price elasticity ranged from -0.6 to -1.2, and decreases in SSB consumption ranged from 5 to 39 kilojoules per person per day given a 10% increase in SSB prices. …”

Lack of Functional Benefit with Glutamine versus Placebo in Duchenne Muscular Dystrophy: A Randomized Crossover Trial by Elise Mok (264326)

“…</p><h3>Methodology/Principal Findings</h3><p>30 ambulant DMD boys were included in this double-blind, randomized crossover trial with 2 intervention periods: glutamine (0.5 g/kg/d) and placebo, 4 months each, separated by a 1-month wash-out, at 3 outpatient clinical investigation centers in France. …”

Table_1_Causal effect of iron status on lung function: A Mendelian randomization study.docx by Zhimin Yu (2258896)

“…</p>Results<p>Based on conservative genetic instruments, MR analyses showed that genetically predicted higher iron (beta: 0.036 per 1 SD increase, 95% confidence interval (CI): 0.016 to 0.056, P = 3.51 × 10⁻⁴), log10-transformed ferritin (beta: 0.081, 95% CI: 0.047 to 0.116, P = 4.11 × 10⁻⁶), and transferrin saturation (beta: 0.027, 95% CI: 0.015 to 0.038, P = 1.09 × 10⁻⁵) were associated with increased forced expiratory volume in 1 s (FEV1), whereas higher transferrin was associated with decreased FEV1 (beta: −0.036, 95% CI: −0.064 to −0.008, P = 0.01). …”

Economic and public health impact of decentralized HIV viral load testing: A modelling study in Kenya by M. de Necker (6407402)

“…The GeneXpert system is a diagnostic point-of-care technology that can quantify, amongst others, HIV VL. …”

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity by Mohamed Abu-Farha (25322)

“…Using this approach, a total of 47 proteins showed at least 1.5 fold change between lean and obese subjects. …”

Spontaneous cephalic version and risk factors for persistent breech presentation: a longitudinal retrospective cohort study by Zehong Zhou (6927917)

“…Female fetus, lateral or fundal placenta, and known uterine malformation was each associated with an increased odd of 1.4 (aOR, 95% CI, 1.11–1.70), 2.4 (aOR, 95% CI,1.50–3.73), 3.1 (aOR, 95% CI, 1.71–5.53) and 8.7 (aOR, 95% CI, 3.84–19.84) times in the persistent breech presentation, respectively.…”