IgE Mediated Autoallergy against Thyroid Peroxidase – A Novel Pathomechanism of Chronic Spontaneous Urticaria? by Sabine Altrichter (224869)

“…IgE-anti-TPO-positive csU patients exhibited significantly higher IgG-anti-TPO levels and lymphocyte counts as well as decreased C4 complement levels.</p> <h3>Conclusion</h3><p>Our findings show that a sizeable subgroup of csU patients expresses IgE antibodies against thyroid peroxidase. …”

Table_1_The burden of poisoning in children hospitalised at a tertiary-level hospital in South Africa.pdf by Mahtaab Khan (17257735)

“…Most (71.3%) children were less than 5 years of age and 55% were male. The incidence of poisoning per 100,000 was highest at 108.4 (95% CI: 104.3–112.6) in 2019 and decreased to 77.3 (95% CI: 73.9–80.7) in 2020 and 59.6 (95% CI: 56.3–62.5) in 2021. …”

Image_2_The burden of poisoning in children hospitalised at a tertiary-level hospital in South Africa.JPEG by Mahtaab Khan (17257735)

“…Most (71.3%) children were less than 5 years of age and 55% were male. The incidence of poisoning per 100,000 was highest at 108.4 (95% CI: 104.3–112.6) in 2019 and decreased to 77.3 (95% CI: 73.9–80.7) in 2020 and 59.6 (95% CI: 56.3–62.5) in 2021. …”

Vascular Complications after Transfemoral Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis by Zouhair Rahhab (6925127)

“…CoreValve (5.98% vs. 7.97%, <i>p</i> = 0.094). Major VC rate was lower in late-phase vs. early-phase studies (5.82% vs. 7.84%, <i>p</i> = 0.048) and a tendency towards a lower rate was seen in intermediate vs. high-risk studies (7.09% vs. 9.62%, <i>p</i> = 0.059).…”

Systematic analysis of <i>CDC73</i> as a suppressor of GCRs selected in the dGCR assay. by Rahul V. Nene (4752033)

“…The semi-quantitative scoring strategy assigns a number between 0 and 5 to each patch depending on the number of papillae (0: no papillae, 1: 1 to 5 papillae, 2: 6 to 15 papillae, 3: 16 to ~150–200 papillae, 4: distinct papillae that were too many or too close together to count, 5: a lawn of papillae covering the entire patch). …”

Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial by Trupti Nagendra Prasad (17266455)

“…<p dir="ltr">Context: Type 2 diabetes (T2D) increases fragility fracture risk despite normal/elevated aBMD, attributed to compromised bone microarchitecture. …”

Data_Sheet_1_Extracutaneous features and complications of the Ehlers-Danlos syndromes: A systematic review.docx by Brent J. Doolan (14490089)

“…Vascular EDS presented with cerebrovascular events (25/153, 16.3%), aneurysm (77/245, 31.4%), arterial dissection/rupture (89/250, 35.5%), and pneumothorax/hemothorax. Chronic pain was the most common miscellaneous complication, disproportionately affecting hypermobile EDS patients (139/157, 88.5%). …”

Biochemical and Mutational Analysis of a Novel Nicotinamidase from <em>Oceanobacillus iheyensis</em> HTE831 by Guiomar Sánchez-Carrón (381982)

“…Mutational analysis was carried out on seven critical amino acids, confirming for the first time the importance of Cys133 and Phe68 residues for increasing pyrazinamidase activity 2.9- and 2.5-fold, respectively. In addition, the change in the fourth residue involved in the ion metal binding (Glu65) was detrimental to pyrazinamidase activity, decreasing it 6-fold. …”

The role of endoscopic doppler probe in the management of bleeding peptic ulcers: a systematic review and meta-analysis by Abhishek Bhurwal (9766157)

“…The risk of rebleeding is significantly higher if the signal persists despite endoscopic therapy (48.5% (95% CI 29.5–67.9%)).</p> <p>The first systematic review and meta-analysis showed that the DOP-US is a beneficial tool in the management of bleeding ulcers and adds valuable information to visual evaluation.…”

Nitric Oxide-Releasing Selective Estrogen Receptor Modulators: A Bifunctional Approach to Improve the Therapeutic Index by Nicole Bechmann (5220479)

“…Growth of ERβ-positive breast cancer and melanoma cells was significantly decreased by treatment with SERM <b>5d</b>. This antiproliferative effect was diminished by the additional release of ^•NO by the corresponding NO-SERM <b>4d</b>. …”

Diagnostic Algorithm for Glycogenoses and Myoadenylate Deaminase Deficiency Based on Exercise Testing Parameters: A Prospective Study by Fabrice Rannou (775170)

“…The lactate/rest ratio at the 10th minute of recovery from exercise displayed the best AUC (1.0) for discriminating between Decreased and Absent MAD activities. The resulting decision tree achieved a diagnostic accuracy of 86.3%.…”

Stage-dependent changes in nuclear gRNA in wild-type and <i>fog-2</i> mutant germ cells. by Bing Sun (44691)

“…<p><b>A.</b> Age-dependent decrease in nuclear gRNA in wild-type hermaphrodites. …”

Table1_Changes in carotid artery texture by ultrasound and elastin features in a murine model.xlsx by Carol Mitchell (3525455)

“…We performed this study to examine how grayscale ultrasound texture features and elastin fibers change in plaque-free segments of the arterial wall in a murine model prone to atherosclerosis.</p>Methods<p>A total of 10 Apoe^tm1Unc/J mice (n = 5 male, n = 5 female) were imaged at 6, 16, and 24 weeks of age. …”

Risk of Shingles in Adults with Primary Sjogren’s Syndrome and Treatments: A Nationwide Population-Based Cohort Study by Jen-Yin Chen (787012)

“…In age-subgroup analyses, incidences of shingles in pSS increased with age and peaked in pSS patients aged ≧60; however, adjusted HRs decreased with age. Compared to control cohorts with no drugs, adjusted HRs for shingles in pSS patients were ranked from high to low as: combined therapies (4.14; 95% CI 3.14–5.45) > immunosuppressants alone (3.24; 95% CI 2.36–4.45) > steroids alone (2.54; 95% CI 2.16–2.97) > no pharmacological drugs (2.06; 95% CI 1.76–2.41). …”

Table1_Does sacubitril/valsartan work in children with heart failure?—a pilot study.pdf by Yahe Xu (17471550)

“…</p>Results<p>Forty-five patients (60% male) with a median age of 7.86 years were enrolled. …”

Presentation_1_A Perioperative Paradigm of Cranioplasty With Polyetheretherketone: Comprehensive Management for Preventing Postoperative Complications.PDF by Zhenghui He (155724)

“…Notably, patients who received the evolving paradigm presented a significantly decreased incidence of postoperative complications from 47.4 to 18.2% (P < 0.01), among which the incidences of subcutaneous effusion, epidural hematoma, and subcutaneous infection decreased significantly.…”

Data_Sheet_1_Evaluation of the Relationship Between Aniseikonia and Stereopsis Using a New Method.docx by Lingxian Xu (12570937)

“…In random-dot based stereograms, stereopsis values increased from 1.29 ± 0.16 at baseline to 2.24 ± 0.23 with 22.5% overall aniseikonia. Overall aniseikonia caused a significantly greater impairment on stereopsis as compared with the changes in meridional directions. …”

Video_1_A Perioperative Paradigm of Cranioplasty With Polyetheretherketone: Comprehensive Management for Preventing Postoperative Complications.MOV by Zhenghui He (155724)

“…Notably, patients who received the evolving paradigm presented a significantly decreased incidence of postoperative complications from 47.4 to 18.2% (P < 0.01), among which the incidences of subcutaneous effusion, epidural hematoma, and subcutaneous infection decreased significantly.…”

Gene expression of VEGF in laser capture microdissected airways (bronchioles) (8A) and parenchyma (8B). by Steven Zhou (440982)

“…<p>VEGF is believed to be a trophic factor for normal lung parenchymal maintenance and is decreased old compared to young animals. …”

HA-Zfr1p localization in <i>Tetrahymena</i> cells with and without brefeldin A treatment. by Jing Xu (15337)

“…<p>(A) Conjugation junction localization of HA-Zfr1p in untreated <i>Tetrahymena</i> cells (B) Conjugation junction localization of HA-Zfr1p decreased in cells treated with brefeldin A, and new signal decorated golgi apparatus closely associated with the mitochondria which are adjacent to cortically aligned basal body. …”