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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
Published 2016“…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …”
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Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…A blend of 25% of each precursor was used and pyrolyzed at 700°C for 2 hrs under N2 gas at a flow rate of 0.1 mL min− 1 using a Lindberg box programmable furnace equipped with an air-tight retort. …”
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Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…Results show that cell viability decreased to 93 ± 3%, 83 ± 6%, 65 ± 4% and 39 ± 3% at 10, 25, 50 and 100 mM of glucose on day 1 with further drastic decrease in cell viability to 73 ± 5%, 61 ± 3%, 35 ± 2%, and 11 ± 6%, respectively, on day 4 compared to the untreated cell. …”
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Effect Of The Apical Ectodermal Ridge On Mitotic Index In Hind Limb Bud Mesenchyme In Bufo Regularis
Published 1991“…The operated bud (80% of cases) showed a decrease in its volume and there was no significant difference in mesenchyme MI. …”
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…The slope suggests that removal of C as CaCO3, organic matter (CH2O) or gas exchange (FCO2) is occurring with a ratio of ΔCaCO3/(ΔCH2O or FCO2) = 1:2.86. The tracer Alk*, defined as the deviation of potential alkalinity (AP) (where AP = TA + 1.26 [NO3]) from conservative potential alkalinity ((ApC), (ApC = S Ap′S′ where A'P and S′ are mean values for the whole surface ocean) has values primarily determined by CaCO3 precipitation and dissolution. …”
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…The slope suggests that removal of C as CaCO3, organic matter (CH2O) or gas exchange (FCO2) is occurring with a ratio of ΔCaCO3/(ΔCH2O or FCO2) = 1:2.86. The tracer Alk*, defined as the deviation of potential alkalinity (AP) (where AP = TA + 1.26 [NO3]) from conservative potential alkalinity ((ApC), (ApC = S Ap′S′ where A'P and S′ are mean values for the whole surface ocean) has values primarily determined by CaCO3 precipitation and dissolution. …”
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Uncovering the Epigenetic Contribution of Protein Arginine Methyltransferase 5 (PRMT5) during Zebrafish Cardiomyogenesis
Published 2020“…This was accompanied by a moderate decrease in blood flow (20%), significantly higher decrease in general cardiac output (65%), and reduction in red blood cells count (50%). …”
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Prevalence of vincristine induced-peripheral neuropathy among Sudanese cancer patients
Published 2016“…Results: Out of 78 patients reviewed, majority were females (n=47, 60.3%). Most of the patients were in the age group of 18-30 (n=27, 34.6%) and 51-60 (n=27, 34.6%) years. …”
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Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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