Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers by Daniel Nettersheim (2866097)

“…<p dir="ltr">In germ cell tumors (GCT), a growing teratoma during chemotherapy with decreasing tumor markers was defined as ´growing teratoma syndrome` (GTS) by Logothetis et al. in 1982. …”

Hyperacetylation of PS1 and BACE1 was suppressed by p300 specific inhibitor curcumin in N2a/APPswe cells. by Xi Lu (288663)

“…<p>(A) the p300 protein was markedly decreased in N2a/APPswe cells after being treated with curcumin; (B) curcumin dramatically reduced the enhancement effect of p300 in N2a/APPswe cells by immunocytochemistry, Magnification 400-fold, Scale bar: 50 µm; (C) curcumin treatment significantly suppressed the HATs activity in N2a/APPswe cells; (D) the Ac-H3 to PS1 and BACE1 promoter regions was much lower in N2a/APPswe cells after being treated with curcumin compared to DMSO (placebo) group; (E) the cellular Ac-H3 in N2a/APPswe cells was statistically significantly decreased after curcumin treatment; (F) N2a/APPswe cells after being treated with curcumin showed reduced binding of p300 to PS1 and BACE1 in N2a/APPswe cells. …”

Data_Sheet_1_Effect of Long-Term Exercise on Liver Lipid Metabolism in Chinese Patients With NAFLD: A Systematic Review and Meta-Analysis.docx by Ye Gao (338234)

“…The findings demonstrated that long-term exercise decreased the level of TG [−0.50, 95%CI (−0.64, −0.36)], TC [−0.55, 95%CI (−0.92, −0.18)], LDL-C [−0.29, 95%CI (−0.43, −0.15)], ALT [−3.45, 95%CI (−6.78, −0.12)], AST [−6.91, 95%CI (−10.00, −3.81)], and body mass index (BMI) of patients who did exercise last more than 6 months [−1.55, 95%CI (−2.32, −0.79)] significantly. …”

Table2_Effectiveness and Safety of Iguratimod Monotherapy or Combined With Methotrexate in Treating Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.DOCX by Dan Ouyang (554436)

“…Pooled results demonstrated as follows: 1) Compared with methotrexate (MTX) alone, IGU alone was superior in improving ACR20 and DAS28-ESR, while having no significant difference in ACR50 and ACR70 [ACR20: (RR 1.15, 95% CI 1.05–1.27, p = 0.004); ACR50: (RR 0.97, 95% CI 0.66–1.44, p = 0.88); ACR70: (RR 0.92, 95% CI 0.45–1.90, p = 0.83); DAS28-ESR: mean difference (MD) −0.15, 95% CI −0.27 to −0.03, p = 0.01]. 2) Compared with MTX alone, IGU + MTX was more effective in improving ACR20, ACR50, ACR70, and DAS28-ESR. …”

Table_1_Tipping point of plant functional traits of Leymus chinensis to nitrogen addition in a temperate grassland.DOCX by Guojiao Yang (12158151)

“…We chose the native, perennial clonal grass, Leymus chinensis in Inner Mongolia steppe, and conducted a field experiment, in which six N addition rates (0, 2, 5, 10, 20, and 50 g N m^–2 year^–1) and five N compound types [NH₄NO₃, (NH₄)₂SO₄, NH₄HCO₃, CO(NH₂)₂, slow-release CO(NH₂)₂] are considered. …”

Image 1_Microbiota composition-based donor selection affects FMT efficacy in a murine colitis model.pdf by Zhongming Dai (16925438)

“…Recipient mice showed increased Firmicutes and Bacteroidota and decreased Verrucomicrobiota, with Lactobacillus and Dubosiella enrichment and normalization of Lachnospiraceae NK4A136 group, Akkermansia, Turicibacter, and Parabacteroides. …”

Data_Sheet_1_Causal Relationship Between Parathyroid Hormone and the Risk of Osteoarthritis: A Mendelian Randomization Study.docx by Guiwu Huang (11183319)

“…</p>Conclusion<p>MR analysis supported a potential causative relationship between decreased serum circulating PTH and a higher risk of hip and knee OA.…”

Data_Sheet_1_Causal Association Between Tea Consumption and Bone Health: A Mendelian Randomization Study.docx by Song Chen (69646)

“…A MR study was conducted to examine the effect of selected single nucleotide polymorphisms (SNPs) and OA, RA, and OP risk. …”

Table_1_Genetic infrapopulation sizes in blood parasites: a pilot quantification of the bottleneck in louse fly vectors.xlsx by Kai Fischer (12841946)

“…They are believed to play a particularly prominent role for parasitic infrapopulations, inhabiting single host individuals, which are often established by very few parasite individuals during transmission. …”

Effects of Successive Rotation Regimes on Carbon Stocks in Eucalyptus Plantations in Subtropical China Measured over a Full Rotation by Xiaoqiong Li (684376)

“…Eucalyptus plantations are primarily planted in successive rotations with a short rotation length of 6~8 years. In order to estimate the carbon-stock potential of eucalyptus plantations over successive rotations, we chose a first rotation (FR) and a second rotation (SR) stand and monitored the carbon stock dynamics over a full rotation from 1998 to 2005. …”

Supplementary Material for: Estimating the Odds of Ulcerative Colitis-Associated Pyoderma Gangrenosum: A Population-Based Case-Control Study by Kridin K. (10202555)

“…The greatest risk of developing PG occurred in the first years following the diagnosis of UC (OR 35.50, 95% CI 4.35–289.60), and decreased thereafter to 10.03 (95% CI 1.83–55.03), 6.69 (95% CI 1.49–30.02), and 10.03 (95% CI 1.83–55.03) at 1–5, 5–10, and 10–15 years after the diagnosis of UC, respectively. …”

Data_Sheet_1_Altered Composition of the Oral Microbiota in Depression Among Cigarette Smokers: A Pilot Study.PDF by Mohammad Tahseen Al Bataineh (9619565)

“…Differential abundance testing between BADS avoidance and activation groups showed the phyla Bacteroidota (effect size 0.5047, q = 0.0037), Campylobacterota (effect size 0.4012, q = 0.0276), Firmicutes A (effect size 0.3646, q = 0.0128), Firmicutes I (effect size 0.3581, q = 0.0268), and Fusobacteriota (effect size 0.6055, q = 0.0018) to be significantly increased in the avoidance group, but Verrucomicrobiota (effect size−0.6544, q = 0.0401), was found to be significantly decreased in the avoidance risk group. …”

Data_Sheet_1_Altered Composition of the Oral Microbiota in Depression Among Cigarette Smokers: A Pilot Study.PDF by Mohammad Tahseen Al Bataineh (9619565)

“…Differential abundance testing between BADS avoidance and activation groups showed the phyla Bacteroidota (effect size 0.5047, q = 0.0037), Campylobacterota (effect size 0.4012, q = 0.0276), Firmicutes A (effect size 0.3646, q = 0.0128), Firmicutes I (effect size 0.3581, q = 0.0268), and Fusobacteriota (effect size 0.6055, q = 0.0018) to be significantly increased in the avoidance group, but Verrucomicrobiota (effect size−0.6544, q = 0.0401), was found to be significantly decreased in the avoidance risk group. …”

Meal and habitual dietary networks identified through Semiparametric Gaussian Copula Graphical Models in a German adult population by Carolina Schwedhelm (2838791)

“…The meal-specific dietary networks were only partly reflected in the habitual dietary network with a decreasing percentage: 64.3% for dinner, 50.0% for breakfast, 36.2% for lunch, and 33.3% for afternoon snack. …”

Presentation_1_The effect of COVID-19 vaccine to the Omicron variant in children and adolescents: a systematic review and meta-analysis.pdf by Wenting Lu (5840954)

“…In addition, VE exhibited a gradual decrease over time, with the significant decline in the efficacy of Omicron for infection before and after 90 days following the 2-dose vaccination, registering 54% (95% CI: 48 to 59%) and 34% (95% CI: 21 to 56%), respectively.…”

Data_Sheet_1_Telemedicine in Low- and Middle-Income Countries During the COVID-19 Pandemic: A Scoping Review.docx by Kareem Mahmoud (12904142)

Secondary* case-patients generated by index case-patients. by Joseph Walker (4341838)

Permeation performance test results of BRA. by Ying Fang (147352)

Metabolic changes associated with AN5568 treatment. by Pieter C. Steketee (466154)

“…WT; wild type untreated, AN5568; wildtype treated for six hours at 10x EC₅₀. C) A schematic to show the metabolites involved in methyltransferase reactions. …”

Table_1_A Cost-Effectiveness and Quality of Life Analysis of Different Approaches to the Management and Treatment of Localized Prostate Cancer.DOCX by Aleksandra Harat (813785)

“…Microsimulations of radical prostatectomy, 3D-conformal radiotherapy, or active monitoring were performed using Medicare reimbursement schedules and clinical trial results for a target population of men aged 50–69 years with newly diagnosed localized prostate cancer (T1-T2, NX, M0) over a time horizon of 10 years. …”