Monofunctional Hyperbranched Ethylene Oligomers by Thomas Wiedemann (1850746)

“…The neutral κ²<i>N</i>,<i>O</i>-salicylaldiminato Ni­(II) complexes [κ²<i>N</i>,<i>O</i>-{(2,6-(3′,5′-R₂C₆H₃)₂C₆H₃-NC­(H)-(3,5-I₂-2-O-C₆H₂)}]­NiCH₃(pyridine)] (<b>1a-pyr</b>, R = Me; <b>1b-pyr</b>, R = Et; <b>1c-pyr</b>, R = <i>i</i>Pr) convert ethylene to hyperbranched low-molecular-weight oligomers (<i>M</i>_n ca. 1000 g mol^–1) with high productivities. …”

DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. by Wen Wen Zheng (17721404)

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qPCR analysis of CK8 knockdown affecting Clauding-1 mRNA expression. by Wen Wen Zheng (17721404)

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PAS staining of intestinal sections from <i>T. spiralis</i>-infected mice pretreated with DAS and Y27632. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of CK8 knockdown blocking the rTsSPc-activated pathway and -reduced TJs expression. by Wen Wen Zheng (17721404)

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IFA, GST pull-down and Co-IP assay of specific binding between rTsSPc and CK8. by Wen Wen Zheng (17721404)

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Intraperitoneal injection protocol for inhibitors (A), inhibitors DAS and Y27632 reduced intestinal permeability (B) and intestinal adult worm burden (C) of infected mice. by Wen Wen Zheng (17721404)

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HE staining showed that DAS and Y27632 alleviated intestinal inflammation in <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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The ROCK1 pathway inhibitor Y27632 prevented rTsSPc from activating the ROCK1 pathway and reducing TJs expression. by Wen Wen Zheng (17721404)

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qPCR (A-D) and ELISA (E-H) detection of inflammatory cytokines in intestine of <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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Intracellular TFV-DP levels detected in PBMC with a single 2-hour TAF pulse and washout. by Christian Callebaut (2276590)

False-positive percentage by days postpartum (A) and parity (B) utilizing the Rapid Visual Pregnancy Test. by Adalaide C. Kline (19226172)

False positive percentage by days postpartum (A) and parity (B) utilizing the OnFarm Pregnancy Test. by Adalaide C. Kline (19226172)

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…The preliminary mechanistic studies indicated that compounds <b>6</b> and <b>43</b> possibly target the HAdV DNA replication process, while compounds <b>46</b> and <b>47</b> suppress later steps of HAdV life cycle. Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC₅₀ = 0.27 μM), significantly decreased cytotoxicity (CC₅₀ = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”

Mechanical data for the two drill bits in the MIPS system (MIPS GS, MIPS WD) and the single drill bits in the MONO system at different feed rates (mm/s). The data are shown as the... by Marsel Ganeyev (21453399)

The dynamics of sickle RBCs interacting with a macrophage under a blood flow with step-wise changes. by Guansheng Li (10170467)

Binding sensogram (a) showing decrease in frequency of crystal immobilised with 1.5 M short aptamer exposed to different concentrations of heparanase. by Suzanne C. Simmons (319222)

Gametocyte numbers can increase (A) or decrease (B, C) even when transmission investment is constant over the time period observed. by Megan A. Greischar (2150737)

“…(A) Gametocyte numbers may increase because the parasite population is expanding, even though the percentage of each cohort committed to transmission remains 50%. …”

Decrease in <i>k</i>_<i>3</i> results in a change in the oscillation from dampened to inflating mode. by Daisuke Ohshima (129662)

STAT3 inhibition in human neural stem cells leads to a decrease in neurosphere formation and proliferation, and an upregulation of Jmjd3 expression. by Maureen M. Sherry-Lynes (3911521)