A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase حسب Thirumal Kumar, D

"…MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …"
احصل على النص الكامل
احصل على النص الكامل

Abnormal brain structure and behavior in MyD88-deficient mice. حسب Schroeder, Patricia

"…Our data indicate a pathophysiological significance of MyD88 for mammalian CNS development, structure, and function.…"
احصل على النص الكامل
احصل على النص الكامل

25-Hydroxyvitamin D serum levels inversely correlate to disease severity and serum C-reactive protein levels in patients with hidradenitis suppurativa حسب Moltrasio, Chiara

"…Subsequently, Guillet et al.5 described an association between vitamin D deficiency and HS severity, also reporting a significant decrease of the inflammatory nodules in patients supplemented with vitamin D. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production حسب Galal, Youssef

"…Studies have suggested that RKIP can be used therapeutically to augment the proapoptotic tendencies in tumor cells, regulate the epithelial-mesenchymal transition (EMT), and decrease metastasis. NKG2D is a C-lectin-type receptor of the NK cell. …"
احصل على النص الكامل
احصل على النص الكامل

Impact of fines type on gas flow using 3D micro-computed tomography حسب Al-Raoush, Riyadh

"…Therefore, there is a need to model and quantify fines impact on multi-phase flow using 3D reconstruction to better understand gas recovery systems. …"
احصل على النص الكامل
احصل على النص الكامل

Impact of fines type on gas flow using 3D micro-computed tomography حسب Al-Raoush, Riyadh

"…Therefore, there is a need to model and quantify fines impact on multi-phase flow using 3D reconstruction to better understand gas recovery systems. …"
احصل على النص الكامل

A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies حسب Mohamed Bakr, Hussain

"…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Vitamin D status affects proteomic profile of HDL-associated proteins and inflammatory mediators in dyslipidemia حسب Hanaa, Mousa

"…Our findings indicated a decrease in HDL-associated apolipoproteins (ApoM and ApoD) in individuals with both dyslipidemia and vitamin D deficiency. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells حسب Abdulrahman, Nabeel

"…Results: The combination of cisplatin and BI-D1870 potentiated the antimigration rate, the activation of caspases-3 and was associated with a significant decrease in RSK1 and ERK expression when compared to cisplatin alone. …"
احصل على النص الكامل
احصل على النص الكامل

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…Our predictions revealed that E17K, R67W, V164G, E319G, R391G, D32Y, L52H, L52R, and W80R were the most pathogenic mutations. …"
احصل على النص الكامل
احصل على النص الكامل

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Al-Sulaiti, Fatima Khalifa

"…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Erratum: ITRAQ-based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes (Journal of Proteome Research (2012) 11 (5527-5537) DOI: 10.1021/p... حسب Kaur, Prabhjit

"…As expected, the diabetic cohort showed an elevation in serum glucose, HbA1c, and insulin levels and a decrease in the serum levels of Vitamin D and HDL .Addition/Correctionpubs.acs.org/jpr © 2013 American Chemical Society 1065 dx.doi.org/10.1021/pr4000224 | J. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A Reverse MultipleChoice Based mLearning System حسب Karkar, AbdelGhani

احصل على النص الكامل
احصل على النص الكامل

An investigation of endometrial vascularity in normally menstruating women and those in other physiological states using 3D ultrasound imaging حسب Khan, Ammar Ahmed

"…The uterine and endometrial volume in the postnatal group were nearly double that of the luteal group (P value <0.01 and 0.014, respectively). There was a significant decrease in flow index in the postnatal group compared to the luteal group (P < 0.01), suggesting low flow intensity in the postnatal group. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comparative Study on Gas-Sensing Properties of 2D (MoS2, WS2)/PANI Nanocomposites-Based Sensor حسب Parangusan, Hemalatha

"…Therefore, the composite PANI/2D-TMDs is a suitable material for NH3 gas detection applications.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

3D FEM Model on the Parameters' Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction حسب Forsat, Masoud

احصل على النص الكامل
احصل على النص الكامل

Study of the Ion Interclation Mechanism in Mxene Membrane for the Water Treatment Applications حسب Helal, Mohamed Ibrahim Elsayed Ali Hussein

"…MXene membrane consists of free-standing layers of a 2D material, namely MXene, which is attracting growing interest due to its conductivity and well-defined interlayer distance and slit-like channels, making it attractive in applications like energy storage and water treatment applications. …"
احصل على النص الكامل

A review on thermochemical biomass gasification techniques for bioenergy production حسب Sapariya, Dharmendra D.

احصل على النص الكامل
احصل على النص الكامل

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact Of Fines On Gas Relative Permeability Through Sand Using Pore Networks From 3d Synchrotron Micro-Computed Tomography حسب Hannun, Jamal Adel Ibrahim

"…There is a knowledge gap of fines effects on gas production from sandy sediments, especially at the pore-scale. …"
احصل على النص الكامل