Bortezomib inhibits infectious DENV production in primary monocytes. by Milly M. Choy (790882)

“…At doses of bortezomib that is minimally toxic to primary monocytes, a significant dose-dependent decrease in virus titers was observed for different strains of all 4 dengue serotypes, (A) DENV1, (B) DENV2, (C) DENV3 and (D) DENV4, after drug treatment in primary monocytes. …”

Image_1_Topical Melatonin Improves Gastric Microcirculatory Oxygenation During Hemorrhagic Shock in Dogs but Does Not Alter Barrier Integrity of Caco-2 Monolayers.tif by Richard Truse (781955)

“…During hemorrhagic shock, gastric microcirculatory oxygenation (μHbO₂) was decreased from 81 ± 8% to 50 ± 15%. Topical treatment with melatonin led to a significant increase in μHbO₂ to 60 ± 13%. …”

Image_2_Topical Melatonin Improves Gastric Microcirculatory Oxygenation During Hemorrhagic Shock in Dogs but Does Not Alter Barrier Integrity of Caco-2 Monolayers.tif by Richard Truse (781955)

“…During hemorrhagic shock, gastric microcirculatory oxygenation (μHbO₂) was decreased from 81 ± 8% to 50 ± 15%. Topical treatment with melatonin led to a significant increase in μHbO₂ to 60 ± 13%. …”

Table_1_Topical Melatonin Improves Gastric Microcirculatory Oxygenation During Hemorrhagic Shock in Dogs but Does Not Alter Barrier Integrity of Caco-2 Monolayers.docx by Richard Truse (781955)

“…During hemorrhagic shock, gastric microcirculatory oxygenation (μHbO₂) was decreased from 81 ± 8% to 50 ± 15%. Topical treatment with melatonin led to a significant increase in μHbO₂ to 60 ± 13%. …”

The Fate of Atrazine in Tropical Environments: Photolysis, Acute Toxicity and Endocrine Disruptor Potential by Polyana S. Barcellos (12881608)

“…Thus, with the degradation of atrazine in water, the medium toxicity may decrease, since DEA and DIA have mean effective concentrations that kill 50% of Artemia salina (EC50) similars to atrazine (13 mg L-1). …”

Effect of sex and acute dosing of (2<i>R</i>,6<i>R</i>)-HNK on withdrawal latency in the hot plate assay. by Todd M. Hillhouse (1359186)

“…<p>(A) There was a temperature-dependent decrease in withdrawal latency for male and female mice. …”

Changes in osteoblast differentiation and function of 4 week-old <i>Lmna</i>^−/− mice. by Wei Li (7081)

“…(<b>C</b>) Sections of plastic embedded proximal tibiae (secondary spongiosa) from <i>Lmna</i>^−/− mice and WT controls (n = 10 per group) were stained sequentially with toluidine blue (upper panels, Magnification ×40) for osteoblasts (black arrows) and osteocytes (red arrows) and ALP (lower panels, Magnification ×20) for osteoblasts (arrows). (<b>D</b>) A significant decrease (−47%) in the number of ALP expressing osteoblasts (N.Ob) and a significant decrease in osteocyte number (N.Ot) (−50%) were seen in <i>Lmna</i>^−/− mice compared with WT^+/+ mice. …”

XAV939 inhibits TNKS PARP-activity in MB cell lines. by Cristiano Renna (585758)

Effect of cell density on cell survival after high-dose irradiation. by Marlon R. Veldwijk (512440)

“…A significant decrease (P<0.0001) in surviving fraction (SF) after 12 Gy was found when seeding 50,000 cells/T25 flask (open symbol) compared with 10,000 cells/T25 flask. …”

Effect of MEHP and PMA on the gene transcription of TSPO, PKCε, PPAR-α, PPAr-β/δ, and PPAR-γ. by Enrico Campioli (336888)

“…Cells were seeded for 24 h before treatment with MEHP (A–C) or PMA (D) and collected after the indicated time points (A) or after 4 days (B–D). qRT-PCR results are normalized to RPS18, expressed in terms of mean and S.E.M. calculated from 3 independent experiments, and presented as fold increase or decrease compared to control. …”

Short-term thalidomide has little effects on AD-like pathology and BACE1 regulation. by Ping He (33281)

Effect of OWB extract and CA on PGE2 release and COX-2 expression in LPS-induced murine peritoneal macrophages. by Durbadal Ojha (475076)

“…The RT–PCR data are expressed as Means ± SD from triplicate experiments. Asterisks indicate a statistically significant decrease (**P, 0.05) in COX-2 expression, compared with infected macrophages.…”

Proliferation and apoptosis evaluation. by Dong Sun (165703)

“…(<b>K</b>) hAFSC group at 14 days after hAFSCs injection: The apoptotic cells were significantly decreased in animals in the hAFSC group (bar, 50 µm). …”

Sensitivity of simulated pathogen diversity to host lifespan and environmental transmission. by Benjamin Roche (84064)

“…The <i>z</i>-axis corresponds to the mean antigenic diversity over the 40-y period. A decrease in environmental uptake rate (<i>x</i>-axis) dramatically reduces mean antigenic diversity (average of the number of strains) and switches the phylogenetic pattern from one that depicts broad coexistence to an immune escape profile. …”

Table_1_Chronic symptoms in patients with unilateral vestibular hypofunction: systematic review and meta-analysis.pdf by Mustafa Karabulut (16506663)

“…In studies that investigated the effect of vestibular intervention, a significant decrease in the estimated mean total DHI scores from 51.79 (95% CI: 46.61–56.97) (pre-intervention) to 27.39 (95% CI: 23.16–31.62) (post intervention) was found (p < 0.0001). …”

The effect of coding time window on metabolically efficient information transmission. by Tomas Barta (8067509)

The E1B19K protein plays an essential role in adenovirus-mediated autophagy. by Sujan Piya (336435)

“…Deletion of E1BK jeopardizes adenovirus-associated autophagy, as assessed by a significant decrease in the LC3 membrane localization. …”

MβCD treatment is effective in sequestering cholesterol from the plasma membrane. by Bárbara Hissa (176168)

Impairment of cognitive memory functions in Auts2 mutant mice. by Kei Hori (840871)

Bcl-xL siRNA effectively knocks down Bcl-xL mRNA and protein and induces platelet apoptosis. by Shifang Yu (721211)

“…<p>Leukocyte-depleted apheresis platelets (LDPs) were transfected with siBcl-xL or negative control siRNA (siNC) at a final concentration of 50 nM. LDPs without transfection were used as blank controls (control). …”