Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Link prediction in 25%, 50% and 75% of the links in networks constructed from all the words in tweets of the emo-net^<i>a</i>, emo-net^<i>b</i>, emo-net<sup><i>... by Sanda Martinčić-Ipšić (4256092)

Bootstrapped LIWC positive word ratio (LWPR) around the hit date for each hurricane and location. by Krishna Bathina (12883820)

Immunocytochemistry showing localization of P53, P21, NF-κB p50, NF-κB p65 and MMP-9 in presence and absence of CY2 in HCT116 cells. by Sumit Kumar Dey (385318)

“…<p>DAPI was used for genomic DNA counterstaining (A) Translocation status of P53 and P21 in control cells (upper panel) and 20 µM CY2 treated cells (lower panel). …”

Comparison of staining efficacy of samples acquired using BD LSRFortessa flow cytometer. by Karine Sonzogni-Desautels (6490919)

“…Increasing levels of parasite burdens (counts in Y axis) show decreasing antibody staining efficacy: > 90% (C); < 90% but > 50% (D); < 50% but > 25% (E); < 25% (F).…”

Fig 3 - by Jianfeng Yang (49036)

SPSS Data set persons with diabetes. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

Feasibility outcomes. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

Participant eligibility criteria. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

Predefined feasibility criteria. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

Demographic characteristics of participants. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

CONSORT flow diagram. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

Original and modified version of intervention. by Joseph Ngmenesegre Suglo (9553147)

“…</p><p>Conclusion</p><p>A contextual family-oriented foot self-care education intervention is feasible, acceptable, and may improve knowledge and self-care with the potential to decrease diabetes-related complications. …”

Assessment of calcium events, pERK levels, NMDA receptor expression and extracellular zinc levels in <i>slc13a5</i> mutants. by Deepika Dogra (21072023)

“…<b>(M, M’, N, N’,</b> Q) Quantification of the fluorescence intensity (CTCF) ratios of Palm-ZP1:CellMask Orange in the plasma membrane. <i>5a</i>^{<i>−/−</i>}<i>;5b</i>^{<i>−/−</i>} larvae show a significant decrease in Palm-ZP1:CellMask Orange CTCF ratio in the plasma membrane compared to WTs. …”

EGC inhibits breast cancer growth and LDH-A expression <i>in vivo</i>. by Zhiyu Wang (282312)

“…The results showed that in both breast cancer xenografts, the expression levels of LDH-A, Ki67 and HIF-1α were decreased in comparison to that in control groups, while apoptosis ratio was elevated in EGC-treated tumor samples detected by TUNEL method; (C) Western blotting analysis showed that the expression of HIF-1α and LDH-A in EGC-treated tumor samples were significantly decreased in comparison with control groups (left panel). …”

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 by Marta E. Capala (652765)

“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”

Effects of A1AR expression on response to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…<p>A: At E9.5, responses to hypoxia in A1AR −/− (n = 15) and A1AR +/− (n = 50) embryos were studied. …”