Representative data from primary HTS. by Pamela Y. Ting (713174)

Expression of Glo-I and MGO in whole rat liver. by Marcus Hollenbach (376231)

LM11A-31's effect on cholinergic dystrophic neurites in cortex of mid-stage APP^L/S mice. by Danielle A. Simmons (621167)

“…Scale bar in photomicrograph A = 50 µm. Quantitative analysis showed that LM11A-31 decreases the total area occupied by the clusters (<b><i>C</i></b>) by decreasing their number (<b><i>D</i></b>) but not the mean area per cluster (<b><i>E</i></b>). …”

Study area (a), location of 52 sediment collection devices (b) and photograph of one of the collection devices in the field, western USA. by Andrew Kulmatiski (833256)

Extended experimental procedures. by Debabrata Tripathy (784509)

Fusion of a granzyme B-mCherry containing lytic granule with the plasma membrane. by Min Ming (785996)

“…(<i>C</i>) The whole-cell membrane capacitance trace (C_m, upper trace) and the camera trigger voltage are shown (lower trace, positive steps indicate shutter opening) versus time. The capacitance step in the C_m trace at time 48.2 s occurs at video frame 535 (arrow).…”

Sensitivity of U251 stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…<p>U251, U251-pCMV-HSVtk, and U251-pGFAP-HSVtk cells were treated with 0, 1, 5, or10 μg/ml of GCV for 5 days. (A–D) Live-cell phase images of U251 parent cells displayed no cytotoxicity up to 10 μg/ml of GCV. …”

Table_1_Effectiveness, Healthcare Resource Utilization and Adherence to Subcutaneous Interferon Beta-1a According to Age in Patients With Multiple Sclerosis: A Cohort Study Using a... by Arthur Allignol (4017428)

“…Adherence (≥80%) was seen to increase with age (77.6%, 18–30 years; 79.6%, 31–40 years; 81.3%, 41–50 years; 84.0%, ≥51 years), at the same time as a non-significant decrease in discontinuation (incidence rate: 79.91, 73.01, 71.75, 68.71%).…”

Table_1_Effectiveness, Healthcare Resource Utilization and Adherence to Subcutaneous Interferon Beta-1a According to Age in Patients With Multiple Sclerosis: A Cohort Study Using a... by Arthur Allignol (4017428)

“…Adherence (≥80%) was seen to increase with age (77.6%, 18–30 years; 79.6%, 31–40 years; 81.3%, 41–50 years; 84.0%, ≥51 years), at the same time as a non-significant decrease in discontinuation (incidence rate: 79.91, 73.01, 71.75, 68.71%).…”

3D spheroids enhance NFAT3 and CXCR4 expression. by Keven Huang (675616)

“…(<b>C</b>) Corresponding to the increase in NFAT3 in 3D spheroids, real-time PCR showed a 30-50-fold increase in CXCR4 mRNA in 3D spheroids when compared to adherent HeyA8 cells. (*, P <0.05 vs Adh, 1-way ANOVA). …”

Frequency-dependent effects of FSK on AHP and Kv2.1 current. by Luis I. Angel-Chavez (736879)

Patterns of nestin, GFAP, and βIII-tubulin expression in U251-pCMV-HSVtk cells. by Elizabeth Wei-Chia Luo (11250668)

“…Immunocytochemistry of nestin (A–F), GFAP (G–L), and βIII-tubulin (M–R, M′–R′) was performed to characterize the identity of surviving cells. …”

Relative gene expression of neural stem cell and lineage specific markers in hMSC populations throughout growth phases. by Rachel K. Okolicsanyi (794011)

Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1 by Pamela Y. Ting (713174)

“…This assay was used in a high throughput screen (HTS) of two small molecule libraries totaling 444,743 compounds. 708 confirmed hits were counter-screened to eliminate off-target inhibitors and reanalyzed to prioritize compounds with IC₅₀ values below 10 μM. …”

TLR4 and RAGE were involved in HMGB1-induced activation of NF-κB in bEnd.3 cells. by Yan Chen (4308)

“…Inhibition of TLR4 and RAGE resulted in a significant decrease in HMGB1-induced NF-κB p65 translocation to nuclei. …”

iBAT characterization of the <i>aP2-Drp1</i>^f/f neonatal mice. by Yuta Ibayashi (20404811)

The effects of purmorphamine and Msi1 knockdown on miR-148a and miR-148b expression. by In-Sun Hong (284033)

“…The expression levels of miR-148a (<b>A</b>) and miR-148b (<b>B</b>) were decreased by purmorphamine treatment. …”

DataSheet_1_Disruptive effects of plasticizers bisphenol A, F, and S on steroidogenesis of adrenocortical cells.docx by Benedikt Pötzl (18854980)

“…However, when combining all three bisphenols, additive effects were detected: e.g. 11-deoxycortisosterone was decreased at doses >10µM (FC 0.27±0.04, p≤0.0001, at 25µM), whereas 21-deoxycortisol was increased by 2.92±0.20 (p≤0.01) at 10µM, and by 3.21±0.45 (p≤0.001) at 50µM. …”

Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat by Da-Zhuang Sun (8650728)

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”