Reproducibility and sensitivity of the method by Axel Schumacher (13710)

“…Median signal intensities of different length oligonucleotides (40–50 bases) that target a specific HpaII restriction fragment in λ DNA reveal that the length of spotted sequences directly influences the spot intensity and therefore the sensitivity of the microarray. () Sensitivity of the CpG-island microarray hybridization. …”

INFS as a transducer of NGF signals to ssTF. by Yu-Wei Lee (432337)

“…NGF stimulates the MAP/ERK pathway resulting in increased RSK1 activity <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068931#pone.0068931-Xing1" target="_blank">[11]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068931#pone.0068931-Silverman1" target="_blank">[13]</a>, which is known to promote the release of newly synthesized FGFR1 from pre-Golgi membranes into the cytosol and accumulation in the cell nucleus <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068931#pone.0068931-DunhamEms2" target="_blank">[33]</a>. RSK1 binding to FGFR1 in the nucleus decreases FGFR1 mobility promoting the FGFR1 nuclear retention accumulation <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068931#pone.0068931-DunhamEms1" target="_blank">[32]</a>. …”

Non-CpG methylation of major satellites. by Julia Arand (155279)

“…Dnmt3 family KO ESCs show decrease of CpA methylation on different sites. C: The graph represents the relative amount of reads per CpG methylation level: grey - reads showing no CpA methylation, black - reads showing CpA methylation. …”

Perturbation Analysis in Different Conditions for different perturbation values. by Giulia Moreni (15063785)

“…The threshold chosen for the figure are: 5%, 10%, 20%, 30%, 40%, 50%, 70%,80%, 90%, 100%, 150%, 200% indicating an increase or decrease of the firing rate of that quantity. …”

Comparison of the Simulated Activities of PI3K, Membrane-Bound PTEN, and the Resulting Behavior of PIP₃ (Composite Screenshot) by Martin Meier-Schellersheim (63389)

“…In the back of the cell (low cAMP concentration), membrane-bound PTEN increases beyond its prestimulus level, resulting in a decrease of PIP₃ below its resting state concentration. …”

Highly Exfoliated MWNT–rGO Ink-Wrapped Polyurethane Foam for Piezoresistive Pressure Sensor Applications by Amit Tewari (4261732)

“…At a higher pressure, the compressive contact of the coated faces of the PU foam results in a sharp decrease in resistance suitable for monitoring of large-scale motion. …”

Effects of adenosine receptor-specific antagonists on responses to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…At both ages, heart rates were not affected by SCH-58261 treatment (A and B). In contrast, at both ages DPCPX elevated heart rates above vehicle levels in normoxic conditions and inhibited hypoxia-mediated heart rate decrease below baseline (A and B). …”

Radar Tracking and Motion-Sensitive Cameras on Flowers Reveal the Development of Pollinator Multi-Destination Routes over Large Spatial Scales by Mathieu Lihoreau (137965)

“…Radar tracking of selected flights revealed a dramatic decrease by 80% (<em>ca.</em> 1500 m) of the total travel distance between the first and the last foraging bout. …”

Transmembrane signaling in cell-derived plasma membrane vesicles. by Luigino Grasso (208932)

“…(C) FRET is detected as fluorescence intensity ratio <i>F_YFP/F_CFP</i> within a single native vesicle; addition of 1 µM agonist APEC significantly increases FRET and subsequent addition of excess of antagonist XAC (10 µM) results in a decrease of the FRET signal. …”

Suppressing amphiregulin expression in tumor-supportive fibroblasts reduces tumorigenicity and amount of mesenchymal cells. by Megha Rajaram (424995)

“…Error bars represent SEM. There was a small decrease in proliferation in the shAREG-2 HFFF2 fibroblast group (not statistical significance, p = 0.06). …”

Mechano–polarity feedback induces spontaneous and robust cell shape change and tissue deformation. by Fu-Lai Wen (11798016)

“…<p>(A) The deviation of apical domain (<i>ℓ</i>_domain) from its homeostatic size () following a decrease (<i>P</i>_<i>total</i> = 0.9) of total concentration of <i>P</i> plotted as a function of time (top) with the corresponding time evolution of <i>ψ</i> and <i>L</i> normalized by their initial values (bottom). …”

Educational nutritional intervention program improved the quality of diet of women with breast cancer in adjuvant treatment by Sheyla DE LIZ (10470671)

“…Also, a rise in the punctuation of calories from solid fats, alcohol, and added sugar was observed (+5.0, p<0.05) due to lower intake of these components. …”

Simulated effects of nifedipine on control and schizophrenic models. by Peter J. Siekmeier (391910)

“…For illustrative purposes, we decreased calcium channel conductance by a maximum of 80%, in increments of 5%. …”

Data Sheet 1_Unveiling spatiotemporal evolution and driving factors of ecosystem service value: interpretable HGB-SHAP machine learning model.docx by Xiangming Xu (420946)

“…The ESV exhibited a slight increase in two counties, while it demonstrated a decrease in the remaining 16 counties at the county scale. …”

Biochemical characterization of the endolysins of the lactococcal phages P008, c2, 1358, and P335. by Frank Oechslin (4825476)

“…The concentrations used corresponded to their specific activities, which were defined as the amount of enzyme needed to decrease the absorbance by 50% in 15 min (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001740#pbio.3001740.s016" target="_blank">S1 Data</a>). …”

Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues by Thomas D. Pfister (107712)

“…Cellular response to Top1 inhibitors is complex, but Top1 target engagement is a necessary first step in this process. This paper reports the development and validation of a quantitative immunoassay for Top1 in tumors.…”

Representative confocal epifluorescent photomicrographs of <i>Schistosoma mansoni</i> sporocysts showing immunolocalization of anti-GST26 and anti-Prx1 antibodies after cultivation... by Marina de Moraes Mourão (189239)

“…By contrast, little difference in fluorescence levels was observed between the nonspecific GFP dsRNA control-treated (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000550#pntd-0000550-g002" target="_blank">Fig. 2C</a>) and Prx1/2 dsRNA-treated (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000550#pntd-0000550-g002" target="_blank">Fig. 2D</a>) sporocysts, reflecting the relatively small decrease (∼50%) observed in immunoblot protein levels. …”

Proteasome function is required for AMPA-induced depotentiation of synaptosomes. by Amadou T. Corera (372197)

“…After 10 min., samples were treated with either the proteasome inhibitor MG-132 (50 µM), lactacystin (10 µM) or control buffer, followed by AMPA (100 µM) for 30 min. to depotentiate synaptosomes as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006021#pone-0006021-g004" target="_blank">figure 4B</a>. …”

Image_1_Amyloid-β Impairs Dendritic Trafficking of Golgi-Like Organelles in the Early Phase Preceding Neurite Atrophy: Rescue by Mirtazapine.TIF by Elsa Fabbretti (103740)

“…We found that short-term (4 h) treatment with Aβ led to a decrease in anterograde trafficking of Golgi vesicles in dendrites of both resting and stimulated (with 50 mM KCl) neurons. …”

120 Years of U.S. Residential Housing Stock and Floor Space by Maria Cecilia P. Moura (781928)

“…While population increased five times over the period, a 50% decrease in household size contributed towards a tenfold increase in the number of housing units and floor space, while average floor space per unit remains surprisingly constant, as a result of housing retirement dynamics. …”