Development of <i>N</i>‑(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrola... by Francesca Intranuovo (2231401)

“…Encouraged by principal component analysis (PCA) data identifying a wide chemical space shared by CB2R and FAAH ligands, we designed a small library of adamantyl-benzamides, as potential dual agents, CB2R agonists, and FAAH inhibitors. …”

Fluid administration rate for uncontrolled intraabdominal hemorrhage in swine by Ujwal R. Yanala (633831)

“…<div><p>Background</p><p>We hypothesized that slow crystalloid resuscitation would result in less blood loss and a smaller hemoglobin decrease compared to a rapid resuscitation during uncontrolled hemorrhage.…”

LD decay plots for A, B, D and whole genome. by Fatima Henkrar (17346528)

Table_1_Effects of Early Changes in Blood Pressure During Intravenous Thrombolysis on the Prognosis of Acute Ischemic Stroke Patients.docx by Zhong-Xiu Wang (9729359)

“…Patients were divided into two groups according to their 3-month prognosis status: patients with mRS ≤ 2 were defined as “favorable outcome group” and those with mRS ≥ 3 as “unfavorable outcome group”. …”

Loss of T37 phosphorylation protects M1 protein from degradation directed by PKG. by Chenxi Wang (284364)

Effect of chronic estradiol plus progesterone treatment on experimental arterial and venous thrombosis in mouse by Marie-Cécile Valéra (4014953)

“…Whereas progestin clearly opposes the proliferative and deleterious long-term actions of estrogen on the endometrium, the interference of progestin on the other estrogen action remains unclear. We previously reported that chronic subcutaneous 17α-estradiol (E2) in mice decreases platelet responsiveness, prolongs the tail-bleeding time and protects against acute thromboembolism. …”

Mitochondrial damage is a key event in the mechanism of oncosis in skeletal muscle cells. by Chengcheng Li (2591632)

Cell viability of canine cells treated with the autophagy inhibitor spautin-1, doxorubicin, or a combination, with spautin-1 applied pre-chemotherapy. by Courtney R. Schott (5904980)

Features and Consequences of Isopropanol Burning off PTFE–rGO Aerogels by Sergey A. Baskakov (11324315)

“…An improved procedure for the preparation of aerogel granules of polytetrafluoroethylene–graphene oxide (PTFE–GO) with a composition of 50:50 (in wt %) and a specific density of 35 ± 2 mg/cm³ is described. …”

Molecular and metabolic percentage changes caused by treatment of pediatric glioblastoma cells with GDC-0941 or PI-103 (5×GI₅₀, 24 hours). by Nada M. S. Al-Saffar (454143)

Anharmonicity and Effect of the Nanostructuring on the Lattice Dynamics of CrSi₂ by A. Moll (9955135)

“…In addition, the GVDOS of nanocrystalline CrSi₂ evidences a spectral weight transfer at low energy, which is related to a decrease in both the Debye temperature and the sound velocities that may be ascribed to an increase in both the interface density and internal strain. …”

Skin defects in <i>Hdh</i>^neoQ50/<i>Hdh</i>^ex4/5 hypomorphic embryos. by Vidya Murthy (6495386)

“…<b>A)</b> At E18.5, following toluidine-blue dye exclusion assay, WT animal shows a functional epidermal barrier but <i>Hdh</i>^neoQ50/<i>Hdh</i>^ex4/5 animal has a compromised epidermal barrier on the ventral surface. …”

Group‑9 Transition-Metal Suboxides Adopting the Filled-Ti₂Ni Structure: A Class of Superconductors Exhibiting Exceptionally High Upper Critical Fields by KeYuan Ma (11569396)

“…We found all three compounds to be type-II bulk superconductors with transition temperatures of <i>T</i>_c = 2.7, 2.8, and 5.4 K and with normalized specific heat jumps of Δ<i>C</i>/γ<i>T</i>_c = 1.65, 1.28, and 1.80 for Ti₄Co₂O, Ti₄Rh₂O, and Ti₄Ir₂O, respectively. …”

No effects of fingolimod on spinal cord glutamate transporter protein levels during EAE. by De-Hyung Lee (356687)

“…At the maximum of EAE, there was a decrease for SLC1A2 (A,B) and SLC1A3 protein levels (C,D) as compared to naïve mice which was restored after fingolimod treatment (3 mg/kg once daily). …”

eGFR trajectories by type of physical activity. by Ronit Calderon-Margalit (584756)

“…We also used Cox proportional hazards models to estimate the associations of physical activity with future eGFR < 90 ml/min/1.73m². …”

A comparison of METH or AMP brain and serum concentrations over time, after a 0.56 mg/kg <i>ip</i> injection of METH, between AAV-scFv6H4, AAV-scFv7F9, and a saline control at day... by Charles E. Hay (5470526)

Stability of H9N2 M1 protein in DF1 cells. by Chenxi Wang (284364)

M1 protein with T37A mutation confers increased pathogenicity and replication of H9N2 virus in mice. by Chenxi Wang (284364)

Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury by Qiang Li (8118)

“…This study undertakes the modification of a 4-(3-(piperidin-4-yl)-1<i>H</i>-pyrazol-5-yl)pyridine structure, leading to the discovery of 4-(3-(piperidin-4-yl)-1<i>H</i>-pyrazol-5-yl)-1<i>H</i>-pyrrolo[2,3-<i>b</i>]pyridine (D25) as a potent and selective MNK inhibitor. …”

Plausibility of the zebrafish embryos/larvae as an alternative animal model for autism: A comparison study of transcriptome changes by Sangwoo Lee (1727713)

“…Specifically, we exposed zebrafish to valproic acid (0, 12.5, 25, 50, or 100 μM), which is a chemical known to induce autism-like effects. …”