Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

“…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC₅₀’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …”

H₂O₂-induced mitochondrial size decrease is prevented by WY pre-treatment in hippocampal neurons. by Juan M. Zolezzi (586604)

KYNA and zaprinast decrease the [Ca²⁺]i plateau phase following an IP3-mediated stimulus in mouse cortical astrocytes. by Rolando Berlinguer-Palmini (491113)

“…<p><b>A</b>) A typical example of KYNA and zaprinast-induced decrease in somatic fluo-3 fluorescence time course measured in three different astrocytes in cultures: control (<i>upper panels</i>), in the presence of 10 μM KYNA (<i>middle panels</i>) or zaprinast 1 µM (<i>lower panels</i>). …”

The switch from PKM2 to PKM1 by OA results from the decrease in Myc, hnRNPA1 and hnRNPA2 expression. by Jia Liu (41593)

Inflammatory conditions decrease CD36 expression and CD36-mediated <i>Pf</i>PEs phagocytosis through downregulation of PPARγ. by David Olagnier (205583)

Arsenotungstate-Nanostructure-Based Derivatives with One-Dimensional Tunnels for Electrochemical Capacitors and Electrocatalytic Hydrogen Evolution by Ran Tian (2449612)

“…The overpotential is 78 mV, and the Tafel slope is 79.3 mV dec^–1 at the current density of 10 mA cm^–2 in alkali solution. The <i>i</i>–<i>t</i> curve test at 170 mV for 24 h did not decrease significantly, revealing its good durability. …”

Arsenotungstate-Nanostructure-Based Derivatives with One-Dimensional Tunnels for Electrochemical Capacitors and Electrocatalytic Hydrogen Evolution by Ran Tian (2449612)

“…The overpotential is 78 mV, and the Tafel slope is 79.3 mV dec^–1 at the current density of 10 mA cm^–2 in alkali solution. The <i>i</i>–<i>t</i> curve test at 170 mV for 24 h did not decrease significantly, revealing its good durability. …”

Arsenotungstate-Nanostructure-Based Derivatives with One-Dimensional Tunnels for Electrochemical Capacitors and Electrocatalytic Hydrogen Evolution by Ran Tian (2449612)

“…The overpotential is 78 mV, and the Tafel slope is 79.3 mV dec^–1 at the current density of 10 mA cm^–2 in alkali solution. The <i>i</i>–<i>t</i> curve test at 170 mV for 24 h did not decrease significantly, revealing its good durability. …”

Transmission electron micrographs (TEM) of thin sections of cells of <i>L</i>. <i>rhamnosus</i> CRL 1505. by María A. Correa Deza (4097602)

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> by Muhammad Saad Yousuf (20745168)

BMT mice had lower plasma insulin levels and glucose tolerance on a HFD. by Saeed Katiraei (3956147)

Predicted targets of miR-337-3p decrease in mRNA expression on over-expression of miR-337-3p. by Liqin Du (158175)

“…<p>(A) Expression levels of miR-337-3p after 72 h transfection of NCI-H1155 cells with 50 nM miR-337-3p mimic as measured by qRT-PCR. …”

Evaluation of ethanol extract of Punica granatum (Pomegranate) peel decrease in viral replication of BoHV-1 in Colorado murine embryos experimentally infected by Eduardo Gimenes Palazzi (5671100)

“…The murine embryos treated with PgEE showed satisfactory results: no morphological changes, cleavage rate similar to controls, despite the detection of the presence of virus by nested PCR and TEM, there was a decrease of the viral titer after the treatment with this extract, which suggests interference of this treatment in the viral cycle BoHV-1 Colorado without altering the embryo development.…”

Fig 4 - by Xiaolan Liu (294511)

Aliskiren decreases fibrosis markers and inhibits changes in apoptosis markers induced by peritoneal dialysis fluids (PDFs) in rat peritoneal mesothelial cells (PMCs). by Juan Pérez-Martínez (324784)

A Small Molecule Inhibitor Selectively Induces Apoptosis in Cells Transformed by High Risk Human Papilloma Viruses by Amy K. Sheaffer (1834249)

“…Testing against a panel of cell lines demonstrated that Compound 1 selectively inhibited replication of all HPV-16, HPV-18, and HPV-31 transformed cell lines tested with 50% Inhibitory Concentration (IC₅₀) values of 2 to 8 μM relative to IC₅₀ values of 28 to 73 μM in HPV-negative cell lines. …”

Intracellular Ca²⁺ signaling and IP3R2 expression are decreased in <i>Tcirg1</i>-knockdown osteoclasts. by Dongyan Zhang (640677)

Figure S2 from Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes by Pauline J. van der Watt (15068109)

Western blots showing increased CaM, CaN and NCX1 levels, and decreased SERCA2 levels in human heart failure. by Raquel Cortés (331424)

EGCG treatment decreases TTR deposition and associated biomarkers in the peripheral nervous system (PNS) of hTTR V30M/HSF mice. by Nelson Ferreira (188837)