A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase by Kenneth W. Yip (257594)

“…This species, a porphodimethene (named PI-16), was found to inhibit UROD in an enzymatic assay (IC₅₀ = 9.9 µM), but did not affect porphobilinogen deaminase (at 62.5 µM), thereby exhibiting specificity. …”

A. Inhibition of the effect of pyruvate on lactate utilization by phenylpyruvate. by Scott John (228011)

“…Recordings in panel B are representative traces of the decrease in intracellular lactate level induced by the addition of pyruvate in the double HKI-HKII kd cells under control conditions (B1) and after a 48hr incubation with the inhibitor of ME1 (ME1*) at a concentration of 50μM (B2). …”

Triaxial test scheme of expansive soil. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

Soil samples during the testing process. by Xuelei Cheng (11725982)

“…Four groups of 16 consolidated drained triaxial shear tests with a confining pressure of 50, 100, 200, and 300 kPa were carried out to study the effects of confining pressure and water content on the deviatoric stress and pore pressure of weak expansive soil with strain. …”

RNAi controls and <i>pyr-GAL4</i> expression (related to Fig 5). by Yuting Lei (9624598)

Systematic errors and base quality score recalibration. by Justin M. Zook (146772)

“…<p>(a) Observed variants in the reads can result from a variety of biological causes and sequencing errors and biases. (1) Random sequencing errors are relatively rare at any given position in the reference, and are generally reflected accurately in the reported base quality score from the instrument. (2) Biological variants that are included in the SNP database (e.g., dbSNP for humans) are excluded from the base quality score recalibration (BQSR), and therefore do not decrease the empirical quality scores. (3) RNA editing can occur at frequencies less than 50%, so it can be difficult to distinguish from SSEs. …”

LIN-2 and FRM-3 regulate the synaptic abundance but not surface expression level of AChRs. by Lei Li (29537)

“…<p>(A-D) ACR-16::RFP and UNC-29::RFP synaptic abundance were decreased in <i>lin-2</i>^<i>null</i> and <i>frm-3</i>^<i>null</i> mutants. …”

<i>SU-like sensitive</i> and <i>SU-like VRC26 early escape</i> viruses are differently neutralized post CD4 attachment. by Lucia Reh (546554)

Period of a stable limit cycle in the AFHN model. by Seth H. Weinberg (154341)

Prolonged Glycemic Adaptation Following Transition From a Low- to High-Carbohydrate Diet: A Randomized Controlled Feeding Trial by Lisa T Jansen (11876618)

“…The number of participants with abnormal glucose tolerance by OGTT remained 10 (of 16) in VLC at start and end but decreased from 17 to 9 (of 25) in both HC groups.</p> <p><b>Conclusions: </b>Physiological adaptation from a low- to high-carbohydrate diet may require many weeks, with implications for the accuracy of diabetes tests, interpretation of macronutrient trials, and risks of periodic planned deviations from a VLC diet.…”

Overexpression of miR-184 disrupts the blood-brain barrier and larval locomotion. by Sravya Paluri (5475260)

Virus evolution alters the entry kinetics of autologous CAP256 viruses. by Lucia Reh (546554)

miR-184 expression in the central and peripheral nervous system. by Sravya Paluri (5475260)

BAG3 is a direct caspase substrate. by Victoria M. Virador (265348)

“…<p>A, B. <u>Deletion of the BAG3 PXXP domain delays loss of BAG3</u>. …”

A Single Molecule Investigation of the Photostability of Quantum Dots by Eva Arnspang Christensen (138327)

“…We further show that β-mercaptoethanol has a dual stabilizing effect on the fluorescence emission of QDs: 1) by increasing the frequency of time that a QD is in its fluorescent state, and 2) by decreasing the photobleaching rate. …”

Demographic and ocular features. by Mingxi Shao (10066570)

“…Pearson analysis revealed significant negative correlations: SOD with anterior chamber depth (r = −0.445, p = 0.012) and H₂O₂ with mean deviation values for the visual field (r = −0.412, p = 0.041). …”

Machine learning model to diagnose PCG. by Mingxi Shao (10066570)

“…Pearson analysis revealed significant negative correlations: SOD with anterior chamber depth (r = −0.445, p = 0.012) and H₂O₂ with mean deviation values for the visual field (r = −0.412, p = 0.041). …”

ROC curves of TAS + SOD + MDA to diagnose PCG. by Mingxi Shao (10066570)

“…Pearson analysis revealed significant negative correlations: SOD with anterior chamber depth (r = −0.445, p = 0.012) and H₂O₂ with mean deviation values for the visual field (r = −0.412, p = 0.041). …”

Adult fat body precursors migrate into the abdomen during metamorphosis. by Yuting Lei (9624598)

Hydrodynamic Treadmill Reveals Reduced Rising Speeds of Oil Droplets Deformed by Marine Bacteria by Vincent Hickl (16947429)

“…Oil droplets with radii 10 < <i>R</i> < 100 μm were colonized and deformed by bacteria over several days before their effective rising speeds were measured. …”