Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-2 by Mrigank Srivastava (94935)

“…(F) Gelatin zymography employing concentrated BAL fluid protein from mock- or bleomycin-treated wild-type mice and cath K tg mice. Data are shown as mean ± SD of n = 3 determinations. (B-F), data represent at least n = 3–5 independent analyses. * indicates < 0.05 versus bleomycin-treated wild-type mice at day 14 post-treatment.…”

Female EIIIA-cFN null mice have decreased accumulation of intracellular lipids at day 2 after PHx. by Bridget Sackey-Aboagye (3221319)

“…(E, F)</b> Quantification of percent Oil Red O covered area, mean +/- SD, * p<0.05. Scale bar, 50 μm. (EIIIA^+/+ = 10; 5 female, 5 male; EIIIA^-/- = 10; 4 female, 6 male).…”

Truncation or mutation of MinE’s membrane targeting sequence decreases the lower limit of the length scale of Min protein patterns. by Simon Kretschmer (1871506)

APB5, but not APA5, decreases proliferating cell numbers in inter-alveolar spaces of lungs. by Masami Kishi (6167105)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)

IFNAR1 is decreased on CD103⁺ DCs in the PPs of mice following treatment with La-IFN-β. by Adelle P. McFarland (229619)

IRE1 depletion decreases heterochromatin, DNA and H3K9me3 methylation, and UHRF1. by Iratxe Zuazo-Gaztelu (21071939)

Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

The surface area of breast tumors in PyMT transgenic mice was decreased after three weeks of voluntary wheel running. by Jorming Goh (490491)

“…Runners have a significant decrease in tumor size in mammary gland 1 after 5 weeks of running (p = 0.03). …”

Differential protective effects of a history of thyroid cancer on breast cancer-specific mortality in patients at age<50years and age≥50years at the diagnosis of breast cancer. by Weiwei Cheng (582223)

<i>Myotis rufoniger</i> genome sequence and analyses: <i>M</i>. <i>rufoniger’s</i> genomic feature and the decreasing effective population size of <i>Myotis</i> bats by Youngjune Bhak (3511349)

“…<i>brandtii</i> bat reference genome at a mapping rate of 96.50% covering 95.71% coding sequence region at 10× coverage. …”

TQ decreases CXCR4 expression on MM cells and CXCL12-induced CXCR4/CD45 association. by Gamal Badr (113166)

Down-regulation of PCNA increases oocyte survival, but decreases proliferation of somatic cells without effects on survival of somatic cells. by Bo Xu (233514)

Placental gene expression at E9.5 and E11.5. by Hui Zhao (7395)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…(<b>H</b>) Quantification of autoradiography for labeled TAG was by ImageJ. <i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”

Mean Capability, Opportunity, and Motivation scores by DAT and country among health care workers. by Kevin Guzman (16474985)

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. by Makoto Ohmoto (3065106)

Effect of different doses (mg/Kg) of the defatted extract (DE) of the leaves of <i>S. malaccense</i> and <i>S. samarangense</i> on serum ALT and AST levels. Data represented as mea... by Fatma A. Moharram (9276104)

Inhibition of autophagic flux increases EtOH-induced oxidative stress, induces mitochondrial depolarization, and decreases cell viability. by Prasanna M. Chandramouleeswaran (3176268)

CyaA decreases the capacity of TLR-stimulated DCs to present soluble antigen to CD4⁺ T cells. by Irena Adkins (173166)