The capacity to neutralize free viruses prior to completion of CD4 attachment varies across bnAb classes. by Lucia Reh (546554)

“…<p><b>A:</b> Schematic of free virus infection of A3.01-CCR5 target cells to measure total and pre-attachment activity of bnAbs. …”

HCV elicits differential expression of circRNAs. by Tzu-Chun Chen (787255)

Effect of obesity on angiotensin II receptors protein expression in mesenteric arteries. by Graziela N. Hagihara (623403)

Stability study results of a) & b) are ACE and CAP at 40°C±2°C/75%RH±5%RH, c) & d) are ACE and CAP at 25°C±2°C/60%RH±5%RH, e) & f) are ACE and CAP at 2–8°C. by Jaganmohan Somagoni (532859)

Table5_Transcriptome and metabolome analyses reveal the responses of brown planthoppers to RH resistant rice cultivar.XLSX by Chunmei Li (272241)

“…The application of insect-resistant rice cultivars is currently one of the principal means of controlling BPH. Understanding the physiological response mechanisms of BPH feeding on insect-resistant rice is the key for maintaining rice yield. …”

Data_Sheet_5_Discovery of Novel Markers for Identifying Cognitive Decline Using Neuron-Derived Exosomes.CSV by Jiacheng Zhong (10433687)

M2b group mean (and standard error) lines of best fit for the normalized integrated wrist flexor EMG values as a function of trial-by-trial foreperiod length. by Christopher J. Forgaard (3210876)

Kinetics of alpaca innate immune responses at the nasal submucosa in response to MERS-CoV Qatar15/2015. by Nigeer Te (7849808)

“…TFs, transcription factors; CKs, chemokines; ADs, adaptors; RT, receptor. MERS-CoV+ and MERS-CoV-, MERS-CoV positive and negative epithelium areas as assessed by IHC, respectively. …”

Image_5_Inflammatory stimuli alter bone marrow composition and compromise bone health in the malnourished host.tif by E. Yaneth Osorio (9226059)

Directed evolution of HIV-1 to utilize CD4^low target cells. by David Beauparlant (3491435)

“…<b>(E)</b> Adaptation to CD4^low target cells results in high resistance to CD4 inhibitor compared to wild type HIV-1 isolates. Comparison of IC50 of CD4-blocking DARPin 55.2 against 41 wild-type HIV-1 strains from different clades (black dots, see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006255#ppat.1006255.s003" target="_blank">S3 Table</a> for details on virus panel and individual IC50 values) and the CD4^low adaptation virus panel (colored dots, see legend) probed by Env pseudovirus infection on TZM-bl cells. …”

The pulmonary hemodynamics and the fluctuation in the serum antibody levels against EXD2 and PHAX peptides in patients with CTEPH before and one year after pulmonary endarterectomy... by Akira Naito (663843)

“…<p>The mean pulmonary artery pressure decreased from 45.5±10.9 to 25.3±7.4 mmHg and the pulmonary vascular resistance decreaseased from 732.0±287.4 to 322.1±157.2 dyne·sec·cm^-5. …”

Mendelian randomization results with COVID-19. by Alish B. Palmos (5857379)

Schematic diagram of STTFP model. by Guozhu Sui (21672798)

Expression of CRYAB in normal and tumor tissue samples across different cancer types. by Rasool Saghaleyni (10526301)

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Dysregulated alternative splicing in DM1 hiNeurons at 10 DPI. by Mougina K. Eltahir (12988153)

“…(d) Scatter plots pertaining to Fig 5c show decreased inclusion of <i>MAPT</i> e2 (top), <i>CSNK1D</i> e9 (bottom left) and <i>MPRIP</i> e9 (bottom right) in DM1 hiNeurons. …”

Effect of obesity on contraction of mesenteric arteries to angiotensin II and norepinephrine. by Graziela N. Hagihara (623403)