IC₅₀ values for inhibition of RdRp activity of NS5B by Nuc (3′-d′CTP) and NNIs. by Sarah E. Boyce (434826)

“…<p>Numbers represent mean and standard deviation of IC₅₀ values determined for each inhibitor against the set of NS5B constructs. Heatmap is colored according to IC₅₀ fold shift relative to Δ21 to show changes in inhibition profile for given NNI across NS5B mutant constructs. …”

Damage-Recovered (DR) cells show increase in H₂S and proliferation rate and exhibit tolerance to damage. by Reiko Sanokawa-Akakura (254909)

Effect of neutralization of HA receptors on TRPV4-induced protein expression of SOX9 and <i>Aggrecan</i> examined by western blotting analysis. by Yoshikazu Ogawa (7164533)

Mean secondary case-patients^a and close contacts per case-patient, and secondary attack rates and test positivity rates among contacts, by age of case-patient. by Joseph Walker (4341838)

Image_5_Xylanase VmXyl2 is involved in the pathogenicity of Valsa mali by regulating xylanase activity and inducing cell necrosis.tif by Xinyue Cui (6291014)

“…VmXyl2 has highly elevated transcript levels during the infection process of V. mali, with 15.02-fold increase. Deletion mutants of the gene were generated to investigate the necessity of VmXyl2 in the development and pathogenicity of V. mali. …”

Table_5_Is periodontal disease a risk indicator for urogenital cancer? A systematic review and meta-analysis of cohort studies.docx by Weiqi Li (419558)

Self-Powered TENG with High Humidity Sensitivity from PVA Film Modified by LiCl and MXene by Jing Wang (6206297)

“…Short-circuit current of the TENG in a wide range of RH (from 50% to 98%) responds very sensitively to humidity fluctuations in the environment and superior adsorption–desorption performance as humidity decreases. …”

Self-Powered TENG with High Humidity Sensitivity from PVA Film Modified by LiCl and MXene by Jing Wang (6206297)

“…Short-circuit current of the TENG in a wide range of RH (from 50% to 98%) responds very sensitively to humidity fluctuations in the environment and superior adsorption–desorption performance as humidity decreases. …”

Photoreceptors undergo substantial changes in TF activity during aging. by Juan Jauregui-Lozano (12024868)

“…<p>A. Heatmap of RNA-seq fold change during aging for significantly differentially expressed genes (DEGs; p-adj<0.05, |FC|>1.5 relative to D10) associated with the GO term “RNA polymerase II-specific DNA-binding transcription factor binding” (GO:0061629). …”

Inhibition of CFTR Cl^¯ channels by fractions from <i>Rhodiola kirilowii</i> (Regel) Maxim. by Lei Chen (54296)

An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos by Sergio Jarque (5698859)

“…<div><p>The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent imaging of reporter gene fluorescence in the thyroid gland of embryos of the transgenic zebrafish line tg(tg:mCherry). …”

Electrical impedance cole parameters. by W. David Arnold (3373874)

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”

Antibody responses to varying doses of rhGAA in null mutation (n = 6) or P545L mutant mice (n = 5). by Sushrusha Nayak (371224)

“…Arrows indicate fold decrease over corresponding 20 mg/kg cohort time point. p<0.05 *, p<0.005 **, p<0.0005 ***, ns = not significant.…”

Potency and breadth of subject immune sera. by Chad D. Nix (8704143)

“…The plot for each serum shows the proportion of viruses neutralized by FRNT₅₀ at a given serum dilution. Each step in each plot represents an FRNT₅₀ value for one virus; as fold serum dilution increases for each serum, the proportion of viruses neutralized decreases by 1/11 (9.1%) as each FRNT₅₀ dilution for each virus is crossed. …”

Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N‑Chelated and Pyridine Ligands by Zhe Liu (77240)

“…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe₂) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt₂) decreased anticancer activity. …”

Table_3_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.XLSX by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Image_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.TIF by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Table_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.docx by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”