Image_1_IL-14α as a Putative Biomarker for Stratification of Dry Eye in Primary Sjögren’s Syndrome.tif by Yichen Liang (585252)

“…The levels of serum BAFF in pSS was significantly higher than in NSDE and HC (p=0.0148 and p<0.0001, respectively, whereas the levels of serum BAFF in RA was only significantly higher than in HC (p=0.001), but the level of BAFF was no significant difference between pSS and RA. In pSS, there was a decrease in the serum levels of IL-14α associated with a longer duration of the disease. …”

The APPLe Study: A Randomized, Community-Based, Placebo-Controlled Trial of Azithromycin for the Prevention of Preterm Birth, with Meta-Analysis by Nynke R. van den Broek (248401)

“…We have now studied the impact of routine prophylaxis with azithromycin as directly observed, single-dose therapy at two gestational windows to try to decrease the incidence of preterm birth.</p><h3>Methods and Findings</h3><p>We randomized 2,297 pregnant women attending three rural and one peri-urban health centres in Southern Malawi to a placebo-controlled trial of oral azithromycin (1 g) given at 16–24 and 28–32 wk gestation. …”

Data Sheet 1_Efficacy and safety of Tanshinone capsule in Acne vulgaris: a systematic review and meta-analysis.docx by Yutong Deng (20908982)

“…We found that Tanshinone capsules can reduce acne recurrence rates [risk ratio (RR) 0.44, 95% confidence interval (CI): 0.34 to 0.57, p < 0.00001]; downregulate levels of necrosis factor-alpha (TNF-α) [ mean difference (MD) 0.44, −10.18, 95% CI: −13.57 to −8.04, p < 0.00001], interleukin (IL) 4 (MD -6.46, 95%CI: −7.14 to −5.77, p < 0.00001), IL-6 (MD -16.14, 95%CI: −30.10 to −2.18, p = 0.02), IL-8 (MD -4.48, 95%CI: −8.30 to −0.65, p = 0.02) and testosterone (MD -14.50, 95%CI: −17.59 to −11.40, p < 0.00001); lower Global Acne Grading System (GAGS) score (MD -4.71, 95%CI: −7.62 to −1.80, p = 0.002); decrease sebum secretion rates (MD -0.29, 95%CI: −0.49 to −0.10, p = 0.003), but the regulation of Luteinizing hormone (LH), Follicle-stimulating hormone (FSH), Estradiol (E₂) is not obvious. …”

Data_Sheet_1_Purification, Characterization, Identification, and Anticancer Activity of a Circular Bacteriocin From Enterococcus thailandicus.docx by Lamiaa A. Al-Madboly (8500359)

“…The aim of the present study was to screen, purify and characterize a hepatotoxic bacteriocin from Enterococcus species. …”

Datasheet2_Genetic association of lipids and lipid-lowering drugs with sepsis: a Mendelian randomization and mediation analysis.docx by Chen Lou (16790187)

“…The indirect impact of ApoA-I explained over 50% of the curative effects of CETP inhibitors in sepsis.…”

Datasheet1_Genetic association of lipids and lipid-lowering drugs with sepsis: a Mendelian randomization and mediation analysis.xlsx by Chen Lou (16790187)

“…The indirect impact of ApoA-I explained over 50% of the curative effects of CETP inhibitors in sepsis.…”

Table_1_What if: A retrospective reconstruction of resection cavity stereotactic radiosurgery to mimic neoadjuvant stereotactic radiosurgery.docx by Gueliz Acker (8882876)

“…In total, 62.5% of cases with an enlargement greater than 5.0 cm³ were smaller tumors (pre-GTV < 15.0 cm³), whereas larger tumors greater than 25.0 cm³ showed only a decrease in post-GTV. …”

Inhibitory effect of theaflavins and catechins on Hla secretion by <i>Staphylococcus aureus</i>. by Anna Goc (316065)

“…Significant differences between treatment and control are represented as # p ≤ 0.05, Δ p ≤ 0.01, * p ≤ 0.001; control—0.02% DMSO; dash line—0.5-fold of change reflecting 50% of expression level of target gene.…”

Video_1_Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants.MOV by Maicon Landim-Vieira (8341251)

“…In contrast, incorporation of 50% WT/50% D132N, which had not been previously reported, decreased Ca²⁺ sensitivity of isometric force. …”

The impact of improved detection and treatment of isoniazid resistant tuberculosis on prevalence of multi-drug resistant tuberculosis: A modelling study by Kamila Romanowski (6260870)

“…</p><p>Conclusion</p><p>Accurate diagnosis and tailored treatment of INHR-TB with LPA led to an almost 50% relative decrease in acquired MDR-TB when compared with an Xpert MTB/RIF strategy. …”

Table_1_Predictive Value of Geriatric Nutritional Risk Index in Patients With Coronary Artery Disease: A Meta-Analysis.pdf by Yu Fan (111503)

Supplementary Material for: Assessment of the Corticospinal Tract Profile in Pure Lower Motor Neuron Disease: A Diffusion Tensor Imaging Study by Sarica A. (7851320)

Data_Sheet_1_The influence of precipitation timing and amount on soil microbial community in a temperate desert ecosystem.pdf by Yao Xiao (227567)

“…The study included five precipitation pattern treatments: a control group (C), as well as groups receiving 50 and 100% of the local mean annual precipitation amount (145 mm) during either the early growing season (E50 and E100) or the late growing season (L50 and L100). …”

LBH589 treatment inhibited the growth of SK-NEP-1 xenograft tumors in nude mice. by Tao Yan-Fang (770096)

“…Down regulation of Bcl-2 and cleaved PARP and caspase 9 was observed after 24 hours of treatment with 50nM and 100nM LBH589. (B) SK-NEP-1 xenograft tumors from the treatment experiment. …”

Analysis of host and interferon-induced responses in glucose/galactose infected with vaccinia virus. by Tyron Chang (9922533)

Table1_Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors.DOCX by Morgan Scott-Dennis (16816950)

“…Agonist activity elicited a decrease in the BRET signal, indicative of receptor activation and G protein dissociation. …”

Time-to-death approach to reveal chronic and cumulative toxicity of a fungicide for honeybees not revealed with the standard ten-day test. by Gilles San Martin (3552875)

“…The concentration and dietary doses of boscalid inducing 50% mortality (LC₅₀ and LDD₅₀, respectively) decreased strongly with the time of exposure: LC₅₀ = 14,729 and 1,174 mg/l and LDD₅₀ = 0.318 and 0.0301 mg bee⁻¹ day⁻¹ at days 8 and 25, respectively. …”

EF-24 induces significant transcriptional changes in K-562 cells. by Ajeet P. Singh (22298432)

Ageing increases Arctic Aβ42 peptide accumulation and toxicity when transcript levels are equalised at different ages. by Iain Rogers (152860)

“…<p>UAS-Arctic Aβ42/+; elavGS/+ females were pulsed, for 1 week, either at 2 or 5 days old with 50 µM RU (RU 50 [2–9d] or [5–12d]) or 20 days old with 200 µM RU (RU 200 [20–27d]). …”

ZC3H18 is highly expressed in EBV by Huanzhou Xu (8129922)