Differences among the classes of CAMs. by Daniel P. Bradley (10306893)

“…Some <i>N</i>-hydroxypyridinedione (HPD) HBV RNaseH inhibitors significantly reduced accumulation of capsids in HBV-replicating cells. A representative HPD <b>1466</b>, with a 50% effective concentration against HBV replication of 0.25 µM, decreased capsid and core protein accumulation by 50–90% in HepDES19 and HepG2.2.15 cells. …”

Synthetic feasibility scores of 20 molecular fragments. by Bin Pan (742525)

Subjects:

The scatter plot of the target variable solubility dataset. by Bin Pan (742525)

Subjects:

Samples with the highest solubility after high-throughput screening. by Bin Pan (742525)

Subjects:

Assessment values of machine learning models. by Bin Pan (742525)

Subjects:

List of datasets in AqSolDB. by Bin Pan (742525)

Subjects:

Schematic workflow diagram of the StackBoost model framework. by Bin Pan (742525)

Subjects:

Comparison of training and predicted values of compound water solubility for different machine learning models: (A) AdaBoost, (B) GBDT, (C) LGBM, (D) RF, (E) XGBoost, (F) RF, and (... by Bin Pan (742525)

Subjects:

Pearson correlation analysis between pairs of feature parameters. by Bin Pan (742525)

Subjects:

Comparison of actual vs predicted values after transfer. by Bin Pan (742525)

Subjects:

List of available information in each column of AqSolDB. by Bin Pan (742525)

Subjects:

3D Scatter plot of features related to water-soluble materials. by Bin Pan (742525)

Subjects:

Workflow diagram of the prediction algorithm framework. by Bin Pan (742525)

Subjects:

Feature importance derived from SHAP analysis. by Bin Pan (742525)

Subjects:

HBV RNaseH inhibitors effects on capsid accumulation occur independent of HBV DNA synthesis. by Daniel P. Bradley (10306893)

Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. by Daniel P. Bradley (10306893)

1466 does not change total yield of capsids during biochemical assembly reactions. by Daniel P. Bradley (10306893)

1466 slows the capsid assembly rate in biochemical Cp149 capsid assembly reactions. by Daniel P. Bradley (10306893)

1466 inhibits capsid accumulation independent of HBV replication. by Daniel P. Bradley (10306893)

Screening HBV RNaseH inhibitors in HepDES19 cell for effects on capsids and core protein. by Daniel P. Bradley (10306893)