Protein and mRNA noise are inversely correlated with abundance. by Roy D. Dar (816541)

Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome by Heon Shin (4559110)

“…Surprisingly, in ALDH6A1-O/E cells, NO was decreased nearly 50% but ROS was increased at a similar level, while the former was restored by treatment with <i>S</i>-nitroso-<i>N</i>-acetyl-penicillamine. …”

Image_1_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.jpg by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_2_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_4_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_3_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_1_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_2_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_3_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_4_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Image_1_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.jpg by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Table_1_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…In adjusted mixed models, functional progression of glaucoma damage was associated with VIMmap (−2.57 dB change in MD per every 3 mmHg increase in VIMmap; P < 0.001) and diurnal MAP dips (changes in the MD ranged from −2.56 to −3.19 dB; P < 0.001). Every 5 mmHg decrease in the nocturnal MAP level was associated with −1.14 dB changes in MD [95% confidence interval (CI), −1.90 to −0.40] and 0.01 larger optic disc cupping (95% CI, 0.01–0.02). …”

Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<... by Li Feng (77923)

“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”

Demographic information of focus group participants. by Katie J. Shillington (16557695)

Table_1_Guanidine acetic acid exhibited greater growth performance in younger (13–30 kg) than in older (30–50 kg) lambs under high-concentrate feedlotting pattern.docx by Wen-Juan Li (1444948)

“…In a brief, the results obtained in the present study suggested that GAA (UGAA and CGAA; 1 g/kg DM) could be applied to improve growth performance in younger (13–30 kg) instead of older (30–50 kg) lambs in high-concentrate feedlotting practice.…”

The prosocial behaviour and kindness of participants over time. by Katie J. Shillington (16557695)

Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i> by Zhihao Chen (513264)

“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”

Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Neutrophil Gelatinase Associated Lipocalin Is an Early and Accurate Biomarker of Graft Function and Tissue Regeneration in Kidney Transplantation from Extended Criteria Donors by Vincenzo Cantaluppi (92814)

“…In the non DGF group, NGAL discriminated between slow or immediate graft function and decreased more rapidly than serum creatinine. NGAL increased after Tac introduction, suggesting a role as marker of drug toxicity. …”

Dietary or gavaged TU-100 and the ginger component decrease enteropooling stimulated by anti-CD3 antibody treatment in specified pathogen free (SPF) and germ free (GF) C57Bl6 mice. by Nobuhiro Ueno (346397)