Search alternatives:
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
ng decrease » _ decrease (Expand Search), we decrease (Expand Search), gy decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
ng decrease » _ decrease (Expand Search), we decrease (Expand Search), gy decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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4421
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Identification of Potent DNA Gyrase Inhibitors Active against Mycobacterium tuberculosis
Published 2022“…Models of complexes of compounds <b>G24</b> and <b>G26</b> bound to the M. tuberculosis DNA gyrase ATP-binding site, generated by molecular dynamics simulations followed by pharmacophore mapping analysis, showed hydrophobic interactions of inhibitor hydrophobic headgroups and electrostatic and hydrogen bond interactions of the polar tails, which are likely to be important for their inhibition. Decreasing compound lipophilicity by increasing the polarity of these tails then presents a likely route to improving the solubility and activity. …”
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Global effects of RG108 on DNA modifications and DNMTs and TETs enzymatic activities in hBMSCs.
Published 2018“…(A) Global methylation was assessed using Imprint Methylated DNA Quantification Kit showing a significant decrease in the RG108 group. …”
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