Red and green fluorescence of <i>M</i>. <i>aeruginosa</i> cells exposed to H₂O₂ and UV, blue, and green light over time relative to control. by Emma T. Brentjens (17295999)

Subjects:

Pendrin gene ablation increases force/cross-sectional area and decreases thickness of the aorta. by Roy L. Sutliff (485240)

Exposure to IQ3A compounds decreases <i>HSP90</i> and <i>KRAS</i> mRNA, protein expression and <i>KRAS</i> transcription. by Hugo Brito (747224)

Estradiol decreased vanillin-induced responses in the ORNs of p5 mice. by Ninthujah Kanageswaran (683924)

“…<p>(A) Representative responses to 100 μM vanillin from Olfr73 positive ORNs in tissue slices were obtained from patch-clamp recordings set to a voltage-clamp configuration (V_h = -56 mV). The amplitude was decreased after 1-min preincubation with 1 nM estradiol. …”

Decreased oscillatory flow decreases <i>klf2a</i> expression. by Julien Vermot (257990)

“…<p>(A) RFF is decreased by alterations in heart rate. …”

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

Porcupine plots of the PCA analysis depicting the movement and altitude of the C-alpha atoms throughout the 50 ns simulation in the native and mutant complexes. by Sneha P. (3926957)

HC-070 decreases anxiety after CCK-4 treatment in an EPM. by Stefan Just (4811358)

Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α_1A-Adrenoceptor Antagonists by Fei Zhao (183673)

“…In this study, two highly selective and potent α_1A-AR antagonists, compounds (<i>R</i>)-<b>14r</b> (IC₅₀ = 2.7 nM, α_1B/α_1A = 640.1, α_1D/α_1A = 408.2) and (<i>R</i>)-<b>23l</b> (IC₅₀ = 1.9 nM, α_1B/α_1A = 1506, α_1D/α_1A = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC₅₀ = 1.9 nM, α_1B/α_1A = 285.9, α_1D/α_1A = 14.4), were identified. …”

Over-expression of DN VPS4 in HEK293T cells leads to increased extracellular α-synuclein and parallel decrease in lysosome. by Takafumi Hasegawa (18204)

“…Each fraction was verified by the presence of a specific marker protein: LAMP-1 (late endosome and lysosome), Rab5 (early endosome), Rab11 (recycling endosome), Hsp90 (cytosol), and BSA (culture medium). …”

The percent of students who, if a science instructor were to tell a joke about a specific subject, might find the joke funny and might find the joke offensive. by Katelyn M. Cooper (5634851)

5-HT supplementation inhibits mitophagy. by Li Gao (131516)

Biologic activity of LY5 in sarcoma cell lines. by Peter Y. Yu (4281448)

Inhibition of PI3K activity decreases uptake of Opa_CEA-expressing gonococci via CEACAM1. by Maike Voges (154488)

MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

Subjects:

Silencing of SphK1, but not SphK2, decreases HPAEC migration by S1P in wound healing ECIS assay. by Evgeny V. Berdyshev (307465)

T310A mutation decreases TSP50’s ability to interact with NF-κB:IκBα complex and to promote NF-κB signaling. by Yu-Yin Li (323887)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

Changes in neuronal morphology after 150 nM sAPP-Fc added to 5DIV neurons. by Stéphanie Chasseigneaux (231744)

“…<p>Morphometric analysis 96 hours after the addition of 150 nM sAPP-Fc to 5DIV neurons shows that: (<b>A</b>) sAPP-Fc induces a significant decrease of primary dendrite number (control (Ctrl) vs sAPP-Fc: p<0.0276). …”