Elemental analysis shows a decreased N content in N stressed cells without a change in their C content. by Steve Dagenais Bellefeuille (654383)

SAA in a 50 year-old woman with HHT and severe liver involvement. by Jacques Sellier (8351355)

The total muscle and motor unit capacities for initial target forces of 15, 50 and 85% until total muscle capacity decreased to 15% MVC (ie. 85% muscle fatigue for each trial). by Jim R. Potvin (4062412)

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Dysregulated alternative splicing in DM1 hiNeurons at 10 DPI. by Mougina K. Eltahir (12988153)

Physostigmine (5 nM) effect on morphological defenses in dependence of <i>Chaoborus</i> and <i>Gasterosteus</i> kairomone (Bonferroni-corrected Mann-Whitney U comparison). by Linda C. Weiss (165793)

Lysine 50 of Tat regulates expression of C5, CRLF2, APBA1, and BDNF genes. by Loreto Carvallo (4167607)

“…<p>THP-1Tat-Flag and THP-1Tat K50ATat-Flag cell lines (generated from independent experiments described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179882#pone.0179882.g005" target="_blank">Fig 5</a>) were differentiated to macrophages with PMA for 24 and 48 hours. …”

Activation of NMDA receptors with D-serine obviously limited the decrease of p-CREB in the hippocampus of the surviving LPS-treated mice. by Shuibing Zhang (4336402)

HDACi decrease NK function. by Matthew Pace (2954127)

Treatment with con-G showed improved neurological scoring and decreased peri-infarct Ca²⁺ microdeposits. by Rashna Balsara (714796)

Evaluation of propidium iodide (PI) uptake by O157 following incubation with hGRNL, bNK2A, and pNKL peptides. by Erika N. Biernbaum (12647386)

(A) Decreasing CaMKII activity by KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L) decreases spontaneous AP firing rate (n = 10 for each drug), cAMP (n = 4 for each drug) and ATP (n = 5 for each drug). by Yael Yaniv (162548)

IC₅₀ of indole alkaloid against alpha-glucosidase [26]. by Atikarn Janthongkaw (17020498)

Concentration of DRS-B2 and [W/F]³-DRS-B2 that inhibits 50% of cell growth (GI₅₀) extracted from Fig 12. by Célia Dos Santos (306471)

TH588 effectively decreases cellular survival in heterogeneous neuroendocrine tumor cells. by Elke Tatjana Aristizabal Prada (833927)

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Thermodynamic parameters of CR adsorbed onto magnetic Co_0.5Mn_0.5Fe₂O₄ nanoparticles. by Xiajun Zhang (3161865)

Subjects:

Trace-weighted images at b = 50 s/mm². by Tobit Führes (12647099)