γδ T cells have similar TCR threshold but enhanced ERK1/2 phosphorylation comparing to αβ T cells. by Hsin-Yuan Cheng (414160)

“…Results were averaged from 5 mice, and shown in mean ± SEM. Lower: Log scaling of αCD3 concentration against % of maximum response was used to calculate EC₅₀. …”

Metformin extends median lifespan via an AMPK and LKB1-dependent mechanism. by Brian Onken (86790)

“…Pooled data for four independent trials with the <i>par-4(it57)</i> mutants show a decrease in median lifespan (9 days for 50 mM metformin plates vs. 10 days for 0 mM metformin; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008758#pone.0008758.s005" target="_blank">Table S1F</a>) and a significantly left-shifted survival curve for 50 mM metformin-treated animals (<i>P</i> = 0.0063, Log-rank; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008758#pone.0008758.s005" target="_blank">Table S1F</a>). …”

Table 1_Influence of different scion-rootstock combinations on sugars, polyamines, antioxidants and malondialdehyde in grafted grapevines under arid conditions.docx by Sonu Krishankumar (10829367)

“…In response to severe drought at 75% and 50% FC, V2 and V5 showed a decrease in MDA accumulation (by 34.2% and 50% in V2 and 23.7% and 57.6% in V5, respectively) compared to 100% FC (0.76 nmoL mL−1 in V2 and 1.18 nmoL mL−1 in V5). …”

Intranasal sufentanil versus intravenous morphine for acute severe trauma pain: A double-blind randomized non-inferiority study by Marc Blancher (6984005)

“…Non-inferiority was demonstrated (<i>p <</i> 0.001 with 1-sided mean-equivalence <i>t</i> test), as the lower 97.5% confidence interval of 0.29 (97.5% CI 0.29 to 1.93) was above the prespecified margin of −1.3. …”

DataSheet1_Analysis of Chinese investment in renewable energy generation in Brazil.PDF by Fenyu Zeng (18969457)

“…There is a rapid growth in wind and photovoltaic power generation over the next 5 years, with growth rates reaching 50.39% and 182.99%, respectively, suggesting that there is potential for a broad range of development. …”

Effect of sex and acute dosing of (2<i>R</i>,6<i>R</i>)-HNK on withdrawal latency in the hot plate assay. by Todd M. Hillhouse (1359186)

“…<p>(A) There was a temperature-dependent decrease in withdrawal latency for male and female mice. …”

Raw data for the forest soil properties. by Ananya Popradit (12520915)

“…<div><p>In a national park in Northeast Thailand, agricultural land has been converted from natural forest by small-scale farmers for cassava agriculture. …”

Raw data for the farmland soil properties. by Ananya Popradit (12520915)

“…<div><p>In a national park in Northeast Thailand, agricultural land has been converted from natural forest by small-scale farmers for cassava agriculture. …”

Changes in osteoblast differentiation and function of 4 week-old <i>Lmna</i>^−/− mice. by Wei Li (7081)

“…(<b>C</b>) Sections of plastic embedded proximal tibiae (secondary spongiosa) from <i>Lmna</i>^−/− mice and WT controls (n = 10 per group) were stained sequentially with toluidine blue (upper panels, Magnification ×40) for osteoblasts (black arrows) and osteocytes (red arrows) and ALP (lower panels, Magnification ×20) for osteoblasts (arrows). (<b>D</b>) A significant decrease (−47%) in the number of ALP expressing osteoblasts (N.Ob) and a significant decrease in osteocyte number (N.Ot) (−50%) were seen in <i>Lmna</i>^−/− mice compared with WT^+/+ mice. …”

Table_1_Diving in the Arctic: Cold Water Immersion’s Effects on Heart Rate Variability in Navy Divers.docx by Richard V. Lundell (8382078)

“…</p>Materials and Methods<p>In order to study ANS responses during diving in Arctic water temperatures, we retrospectively analyzed repeated 5-min heart rate variability (HRV) measures and the mean body temperature from dives at regular intervals using naval diving equipment measurement tests in 0°C water. …”

ORP8 KO BMDMs have reduced excretion of pro-inflammatory cytokines and reduced expression of co-stimulatory factors. by Erik van Kampen (649704)

“…Expression of co-stimulatory factors CD40 and CD80 on BMDMs from ORP8 BM and WT BM was measured using FACS C) The percentage of unstimulated BMDMs expressing CD40 was decreased in the ORP8 KO group. (** P<0.01, N = 5) D) After stimulation with LPS, the percentage of BMDMs expressing CD80 was decreased in the ORP8 KO group (* P<0.05, N = 5). …”

Automated image analysis algorithm quantifies changes in synapses development. by Thomas J. F. Nieland (535564)

“…The data in (C) present the mean and standard deviation of the primary screen. …”

A Randomized, Crossover Study to Evaluate the Pharmacokinetics of Amantadine and Oseltamivir Administered Alone and in Combination by Dennis Morrison (272746)

“…<div><h3></h3><p>The threat of potential pandemic influenza requires a reevaluation of licensed therapies for the prophylaxis or treatment of avian H5N1 infection that may adapt to man. Among the therapies considered for use in pandemic influenza is the co-administration of ion channel and neuraminidase inhibitors, both to potentially increase efficacy as well as to decrease the emergence of resistant isolates. …”

Suitable Days for Plant Growth Disappear under Projected Climate Change: Potential Human and Biotic Vulnerability by Camilo Mora (208409)

“…We show that although the global mean number of days above freezing will increase by up to 7% by 2100 under “business as usual” (representative concentration pathway [RCP] 8.5), suitable growing days will actually decrease globally by up to 11% when other climatic variables that limit plant growth are considered (i.e., temperature, water availability, and solar radiation). …”

Maintenance of Hypertensive Hemodynamics Does Not Depend on ROS in Established Experimental Chronic Kidney Disease by Diana A. Papazova (522248)

“…Compared to age-matched, sham-operated controls all ablated rats showed proteinuria, decreased glomerular filtration rate (GFR), more renal damage, higher mean arterial pressure (MAP), RVR and excretion of oxidative stress markers and hydrogen peroxide, while excretion of stable nitric oxide (NO) metabolites tended to decrease. …”

The −615 to −624 bp region of the ET_B receptor promoter is the AP-1 binding site in HNPE cells. by Shaoqing He (143800)

“…<p><b>A.</b> 0.5 µg of ET_B receptor promoter constructs and 0.5 µg of either the empty vector or c-Jun expressing plasmid DNA were co-transfected into HNPE cells in each well of a 12-well plate. …”

Long-term patency and clinical outcome of the transjugular intrahepatic portosystemic shunt using the expanded polytetrafluoroethylene stent-graft by Xuefeng Luo (538771)

“…TIPS-related complications occurred in 67 patients (13.5%) during the index hospital stay. TIPS creation resulted in an immediate decrease in mean portosystemic pressure gradient from 23.4 ± 7.1 mmHg to 7.6 ± 3.5 mmHg. …”

ER stress reduces AKT phosphorylation at Thr308, but increases it at Ser473, and alters target substrate specificity. by Hong Wa Yung (227056)

“…Phosphorylation status is presented as the ratio between phosphorylated and total protein. Data are mean±SEM from 3 to 5 independent experiments. ** and * indicate <i>P<</i>0.01 and P<0.05. …”

Confirmation of Functionality of Constructs and Model System Used by Maarten F Bijlsma (380371)

“…</p> <p>(C) Shh concentration in medium is below the detection limit (5 ng/ml) of Western blotting. Medium was spiked with decreasing concentrations of recombinant Shh, and blotted along with a 4× concentrated medium sample obtained from C3H/10T1/2 fibroblasts (incubated for 16 h at a volume-to-surface ratio identical to the mix-and-match and medium transfer experiments).…”

A degradation debt? Large-scale shifts in community composition and loss of biomass in a tropical forest fragment after 40 years of isolation by Rakan A. Zahawi (530432)

“…Turnover was high: 22.9% of stems in the first survey were lost, and 27.8% of stems in the second survey represented new recruits. Mean tree diameter decreased significantly and there was a 10% decrease in overall biomass. …”