Typical Time Courses of the Number of Active Receptor Complexes upon Addition of TGF-β by Jose M. G Vilar (27466)

“…</p><p>(F) Behavior of the model with the same parameter values as in (A), with the exception of the efficiency of recycling of active receptors that has been decreased to <i>α =</i> 0.5. …”

Fig 1 - by M. Latorre (8840546)

“…<p>Fully developed, mechanobiologically equilibrated, axisymmetric dilatations of an initially cylindrical aortic segment caused by a mild (first column) or severe (second column) localized (via the respective parameter <i>ϑ</i>_{<i>central</i>} in Eq (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008273#pcbi.1008273.e024" target="_blank">9</a>)) loss of elastic fiber integrity (first row, parameter <i>c</i>^<i>e</i>, mild 32% and severe 62% reduction), decrease in collagen cross-linking (second row, parameter , mild 9%, severe 23% reduction), loss of smooth muscle contractility (third row, parameter <i>T</i>_<i>max</i>, mild 60%, severe 100% reduction), compromised mechanosensing (fourth row, parameter <i>δ</i>, mild 7.5%, severe 18.5%, absolute), or compromised mechanoregulation (fifth row, parameter <i>G</i>^<i>c</i>, mild 0.4%, severe 1.2%, relative change), with the risk factors of hypertension (third column, 50% increase in blood pressure) and aortic aging (fourth column, uniform 30% loss of elastic fiber integrity) superimposed on the mild insults. …”

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…The mechanistic interpretation of developed models explains the role of different structural attributes in predicting the pIC₅₀ of pyrazole sulfonamides extracted from the crystal structure of Leishmania major N-myristoyltransferase (NMT) along with co-crystallized myristoyl-CoA and ligands NMT106, NMT157, NMT187 and NMT236 (PDB ID: 4A2Z, 4A30, 4A32, 2WSA). …”

The Protein <i>O</i>-glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in <i>Drosophila</i> by Amanda R. Haltom (664189)

“…The intracellular accumulation of Eys and the IRS defect worsen in <i>rumi</i> mutants raised at a higher temperature, and are accompanied by a ∼50% decrease in the total level of Eys. …”

Table_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.docx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

DataSheet_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

Estrogen Receptor inhibition prevents estradiol-17ß-d-glucuronide (E17G)-induced endocytic internalization of Abcb11 and Abcc2 in perfused rat liver. by Ismael R. Barosso (116985)

“…Distribution profiles of livers treated with E17G+ICI was similar to control and indicated a significantly decreased of Abcb11 and Abcc2 internalization (P<0.01 versus E17G). …”

Data_Sheet_1_Antimicrobial Resistance and Livestock Trade for Low and Middle Income Countries: Regional Analysis of Global Coordination Policies.pdf by Charalampos Avraam (10361288)

“…We found that a user fee that increases the price of antimicrobials by 50% globally leads to a 33% reduction in global antimicrobial use. …”

BMI and Lifetime Changes in BMI and Cancer Mortality Risk by Niloofar Taghizadeh (724983)

“…Obesity at baseline was associated with a higher risk of any cancer mortality [all subjects (1.23 (1.01-1.50)), and females (1.40 (1.07-1.84))]. …”

Seasonal patterns of Asthma medication fills among diverse populations of the United States by Kedir N. Turi (4866565)

“…<i>Methods</i>: We conducted a retrospective cohort study of asthmatics 4–50 years of age and enrolled in three diverse health insurance plans. …”

Loss of parasympathetic cholinergic neurons innervating the liver. by Jiyeon Hwang (19747297)

“…Left panel: control. Scale bar, 50 μm. (E, F) Summary plots showing a significant decrease in hepatic (control, <i>n</i> = 7 mice; experimental mice, <i>n</i> = 6 mice), but not plasma (control, <i>n</i> = 11 mice; experimental mice, <i>n</i> = 8 mice), ACh contents in ChAT^{Cre + AAVrg-FLEX-dtA} mice compared to the controls. …”

CCL21 Concentration Gradients in B Cell Follicles in Lymph Nodes by Takaharu Okada (99)

“…Pixel intensity was measured using Metamorph software after converting colored pixels to gray scale. A decrease in transmitted light intensity indicates an increase in CCL21. …”

DataSheet_2_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

Presentation_1_Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.pdf by Emilia Boiadjieva Knöpfel (6795341)

“…Correspondingly, deletion of LAT2 induced a dramatic decrease in lens essential amino acid levels that was modulated by TAT1 defect. …”

Table 1_Short term heat stress alters the hematological, immunological, and plasma metabolomic responses of Florida Cracker sheep.xlsx by Makenzie Harrison (22152829)

“…Plasma samples were used for analysis of IgA level and to conduct targeted metabolomics. Targeted metabolomics analyzed a total of 50 metabolites, including organic acids, amino acids, hexoses, lipids, and carnitines. …”

Table_2_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.docx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

Evaluation of PIT effects in a disseminated peritoneal model. by Kazuhide Sato (662171)

“…(C) Quantitative analysis of GFP fluorescence intensities showed significant decreases by day 3 after PIT between control group and PIT group (n = 5 mice in each group, (*p = 0.0295<0.05 vs. …”

Galactosemia patient characteristics. by Inge Timmers (292367)

“…</p>1<p>GALT activity was measured at diagnosis;</p>2<p>In case the GALT activity is not reported, it was confirmed by the treating physician to be severely decreased;</p>3<p>ND = not detected;</p>4<p>Urine levels were measured within three months of testing;</p>5<p>At some point in life;</p>6<p>Q188R/L195P (n = 4) or Q188R/S135W (n = 1);</p>7<p>L195P/K229N (n = 3) or 400Tdel/unknown (n = 2).…”

Modifying the network architecture. by Sara Hooshangi (205828)

“…In the presence of high AI-2 concentrations, REG (like LsrR) binds AI-2-P and the auto-regulation effect of REG decreases. B) The <i>lsr-</i>operon promoter activity is plotted as a function of AI-2 concentrations at a single time point (hour 5) for all three sub-networks (<i>lsr</i>-operon, <i>lsrR</i> and <i>lsrK</i> knock-outs) and also for the intact network. …”

Relationship between periodic patterning and receptive field refinement. by James E. M. Bennett (787674)

“…Incremental changes in wave speed can continually refine RFs while maintaining a single subfield structure. Shown is the development of a RF, averaged over 16 trials, during which the wave speed is first set to 4 mm/s and then decreases to 2.5 mm/s, after which the RF decreases in size. …”