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point decrease » point increase (Expand Search)
teer decrease » greater decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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12661
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12662
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12663
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12664
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12665
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12666
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12667
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12668
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12669
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
Published 2016“…Among them, <b>14k</b> exhibited most potent activity, with IC<sub>50</sub> values of 3–9 nM against six cancer cells, which displayed a 3.8–8.7-fold increase in activity when compare with compound <b>2</b>. …”
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12670
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12671
WNT7A Regulation by miR-15b in Ovarian Cancer - Fig 5
Published 2016“…<p>(A) 5-aza-2’-dC treatment induces <i>miR-15b</i> expression (left) and decreases <i>WNT7A</i> expression (right) in OvCa cells. …”
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12672
Effect of high-intensity interval training on glycemic control in adults with type 1 diabetes with overweight or obesity: a randomized controlled trial with partial cross-over
Published 2020“…In participants who undertook at least 50% of the prescribed HIIT intervention, the HbA1c reduction was significantly greater than control (HIIT -0.64 ± 0.64% (n=9), control -0.14 ± 0.48% (n=15), p=0.04). …”
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12673
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12674
Attenuation of CDK expression and cyclin D-CDK4/6 activity by androgen in PC3-Lenti-AR.
Published 2015“…(E) In comparison to control samples, DHT treatment for 24 hours significantly decreased CDK4 and CDK6 mRNAs and pre-mRNAs 1.5 fold or more and increased CDKN1A mRNA and pre-mRNA 2 fold or more, suggesting AR-mediated regulation of transcription at these genes, n = 3. …”
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12675
Stereospecific CO<sub>2</sub> Copolymers from 3,5-Dioxaepoxides: Crystallization and Functionallization
Published 2014“…As a model monomer of 3,5-dioxa-epoxides, 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane (CXO) was studied in detail in the asymmetric copolymerization with CO<sub>2</sub>. …”
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12676
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12677
Rate-limiting enzymes tyrosine hydroxylase (catecholamines) and tryptophan hydroxylase (5-HT) post-stress.
Published 2014“…<p>Tyrosine hydroxylase elevation in the PFC (A) and hippocampus (B) substantiated the findings of elevated levels of NE and DA, while down-regulated tryptophan hydroxylase in the PFC (C) and hippocampus (D) confirmed decreased levels of 5-HT. All data are presented as mean ± SEM. …”
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12678
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12679
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12680