Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

“…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC₅₀ = 22.02 nM). …”

Information of core targets. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

Composition of Scutellaria Barbata. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

GO function enrichment analysis. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

KEGG functional enrichment analysis. by Guobing Wang (288885)

“…Transwell Experiments to verify the migration rate of Hela cells at different time points of action. Hela cell apoptosis was determined by a Tunel assay. …”

The HMR C-terminus is required for HMR localization in proximity to centromeres and HP1a-bound chromatin. by Andrea Lukacs (3752956)

cART up-regulated iNOS and TNF-α in HIV-Tg rats—Blockade by Mg. by Lama ElZohary (6250859)

N⁶-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon blac... by Bin Han (45760)

“…We found that both of m⁶A modifications of pri-miRNA-126 and its binding with DGCR8 were decreased after CB treatment, which resulted in the reduction of mature miRNA-126 accompanied by accumulation of unprocessed pri-miRNA-126. …”

GEO database download data (GSE75595) analysis and identification of gastric cancer cell line super-enhancer and prediction of target genes. by Hong Du (117108)

Image_5_Transcriptome and miRNome Analysis Provide New Insight Into Host Lipid Accumulation, Innate Immunity, and Viral Persistence in Hepatitis C Virus Infection in vitro.TIF by Chong Li (120471)

Table_5_Transcriptome and miRNome Analysis Provide New Insight Into Host Lipid Accumulation, Innate Immunity, and Viral Persistence in Hepatitis C Virus Infection in vitro.XLS by Chong Li (120471)

HIV-1 expression plus cART promoted hepatic expression of sterol regulatory element-binding protein-1 (SREBP-1)—Suppression by high Mg diet. by Lama ElZohary (6250859)

Enrichment of <i>Efnb1</i> and <i>Efnb2</i> mRNA in POMC neurons during postnatal development of glutamatergic inputs. by Manon Gervais (9708032)

Phenotypic characterization of the mutant. by Hui Zhang (7197)

cART raised plasma total triglyceride and total cholesterol levels in HIV-Tg rats—Attenuation by high Mg diet. by Lama ElZohary (6250859)

Loss of <i>Efnb1</i> in POMC-expressing progenitors causes glucose intolerance in males. by Manon Gervais (9708032)

Table_5_Longitudinal Variations of CDC42 in Patients With Acute Ischemic Stroke During 3-Year Period: Correlation With CD4+ T Cells, Disease Severity, and Prognosis.docx by Xiao Cheng (203504)

cART suppressed Nfr-2 expression and altered responses of heme oxygenase-1 (HmOX-1) and guthathione-S-transferase (GST) expression in HIV-Tg rats. by Lama ElZohary (6250859)

Loss of C1-FDX results in a reduction of the CI and CV activity. by Baoyin Chen (2635399)

Loss of <i>Efnb2</i> in POMC-expressing progenitors causes impaired gluconeogenesis in males. by Manon Gervais (9708032)