Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes by Pavel Štarha (490367)

“…Complexes showed high <i>in vitro</i> cytotoxicity against nine human cancer cell lines (IC₅₀ ranging from 0.4 to 12.8 μM), including the <i>cisplatin</i>-resistant ovarian cancer cell line (A2780R; IC₅₀ = 1.0–3.5 μM). …”

B-THP-Ts bind to C-terminal GFP-PTP tagged F₁ α- and β- subunits. by Lindsay B. Tulloch (1266861)

2‑(Fluoromethoxy)-4′‑(<i>S</i>‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D₁ Receptor for... by Javier García-Cárceles (2073898)

2‑(Fluoromethoxy)-4′‑(<i>S</i>‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D₁ Receptor for... by Javier García-Cárceles (2073898)

2‑(Fluoromethoxy)-4′‑(<i>S</i>‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D₁ Receptor for... by Javier García-Cárceles (2073898)

2‑(Fluoromethoxy)-4′‑(<i>S</i>‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D₁ Receptor for... by Javier García-Cárceles (2073898)

2‑(Fluoromethoxy)-4′‑(<i>S</i>‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D₁ Receptor for... by Javier García-Cárceles (2073898)

Effects of compounds on mitochondrial membrane potential. by Lindsay B. Tulloch (1266861)

Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA) by Pascale Vonaesch (149522)

“…<div><p>Stunting remains a major public health concern worldwide. Although its global prevalence is slowly decreasing, the actual number of affected children is still rising in Sub-Saharan Africa. …”

Effect of potassium channels blockade on relaxation induced by CNP. by Carolina Caniffi (444744)

Different scenarios of hidden hearing loss have additive effects on SGN activity. by Maral Budak (6680351)

“…<p>(A) Sound-evoked CAPs of SGN fiber populations with different myelinopathy and synaptopathy scenarios at 70dB SPL, averaged over 50 simulations (dashed lines correspond to the peaks of each CAP, labeled with the same colors as the CAPs). …”

DAF-16 FOXO localizes to vesicles in intestinal cells. by İçten Meraş (13184380)

Keeping constant channel number as length of unmyelinated segment, <i>L</i>_<i>u</i>, is increased leads to similar effects on cumulative CAP as keeping constant channel... by Maral Budak (6680351)

“…<p>(A)Sound-evoked CAPs of SGN fiber populations with varied <i>L</i>_<i>u</i> at 70dB SPL, averaged over 50 simulations (dashed lines correspond to the peaks of each CAP, labeled with the same colors as the CAPs). …”

Maintaining channel density at the heminode as its length, <i>L</i>_<i>h</i>, is varied reduces effects on cumulative CAP compared to keeping constant channel number. by Maral Budak (6680351)

“…<p>(A) Sound-evoked CAPs of SGN fiber populations with varied <i>L</i>_<i>h</i> at 70dB SPL, averaged over 50 simulations (dashed lines correspond to the peaks of each CAP, labeled with the same colors as the CAPs). …”

Manager’s characteristics. by Martina Wallberg (16052714)

Proline metabolism in PF <i>T</i>. <i>brucei</i> and reactions catalysed by potential B-THP-T targets. by Lindsay B. Tulloch (1266861)

Loop in the IB domain drives ParM monomer opening. by Natalie Ng (6560246)

“…Two simulations (ParM-ATP-2,3) consistently exhibited opening angles of ~102° after 50 ns and maintained that value, whereas in the other simulation (ParM-ATP-1), the opening angle increased beyond 105° after 100 ns and then eventually decreased to ~103° in the last 20 ns of the 200-ns simulation (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006683#pcbi.1006683.s004" target="_blank">S4A Fig</a>). …”

Table_1_Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An in-vitro, in-vivo, and in-si... by Nasiara Karim (6085445)

“…Asparacosin A also inhibited the human recombinant COX-2 enzyme and caused a dose-dependent decrease in the levels of TNF-α, IL-1β, and PGE2 in the carrageenan-induced paws. …”

The effects of variations in coagulation potential on atherogenesis in a spontaneous atherosclerosis model at 35 weeks on a regular chow diet. by Julian I. Borissoff (280594)

Labelling and detection of B-THP-T target(s). by Lindsay B. Tulloch (1266861)