Inflammation and Gli2 Suppress Gastrin Gene Expression in a Murine Model of Antral Hyperplasia by Milena Saqui-Salces (126581)

“…Using a mouse model of constitutively active epithelial GLI2 expression, we found that activated GLI2 repressed <em>Gast</em> expression but induced <em>Il-1β</em> gene expression and proliferation in the gastric antrum, along with a reduction of the number of G-cells. …”

Negative Epistasis between Sickle and Foetal Haemoglobin Suggests a Reduction in Protection against Malaria by Bruno P. Mmbando (737804)

“…An increase in HbF was associated with a decrease in risk of malaria OR=0.50 (95%CI: 0.28, 0.90; p=0.021) in HbAA, whereas for HbSS the risk of malaria increased OR=2.94 (1.44, 5.98; p=0.003). …”

Differences in (A) aboveground biomass and (B) leaf nitrogen content among the three dominant vegetation classifications. by Mary Alldred (2512081)

“…Boxplots represent the median and interquartile range, and whiskers extend to the most extreme point within 1.5 times the interquartile range. (C) The nitrogen content of leaves decreases with increasing biomass in <i>Typha</i>-dominated (n = 24, slope_SMA = -8.34, r = 0.59, p = 0.0023) and removal communties (n = 6, slope_SMA = -9.92, r = 0.80, p = 0.0549), indicating nutrient limitation. …”

Phenotypic characterization of HG-treated primary tubular cell cultures. by Barbara Torsello (4594873)

Endocrine Determinants of Changes in Insulin Sensitivity and Insulin Secretion during a Weight Cycle in Healthy Men by Judith Karschin (696523)

“…Weight regain-induced decrease in postprandial IS correlated with increases in adiponectin, fT3, TSH, GL of the diet and a decrease in ghrelin levels (r-values between -0.40 and 0.83, p<0.05) whereas increases in early and total insulin secretion were associated with a decrease in leptin/adiponectin-ratio (r = -0.52 and r = -0.46, p<0.05) and a decrease in fT4 (r = -0.38, p<0.05 for total insulin secretion only). …”

Photomicrographs of prostate sections stained with H&E and toluidine blue. by Rabab Ahmed Rasheed (12536918)

ITR calculation for hypothetical cases of typing a 10 character sequence with error correction in 10 minutes. by William Speier (475066)

Performance of CNN models. by Fang-Rong Hsu (13983021)

Correlation between angles representing metatarsal alignment and relevant variables when standing on the non–dominant leg. by Akiko Imura (7245170)

Image_1_Oat polar lipids and sunflower lecithin similarly improve cardiometabolic risk markers and appetite controlling hormone responses after breakfast and a subsequent lunch. A... by Mohammad Mukul Hossain (20128593)

“…Dietary intake of bioactive compounds found in foods are linked to a decrease likelihood of these disorders. For this purpose, a randomized crossover meal study was performed to compare the postprandial metabolic effects of lecithin and oat polar lipids in healthy subjects.…”

Influence of Sample Stability on Non-target Analysis during Long Batch Acquisitions by Bastian Schulze (9754985)

“…The sample remained in the cooled autosampler and was re-analyzed 47 times over 24 h and daily over the following 5 days (<i>n</i> = 15 data points). Detected features were classified as “formed,” “increased,” “unchanged,” “decreased,” or “eliminated.” …”

Role of psychosocial status in predicting health-related quality of life at 1-year follow-up among newly diagnosed people living with HIV by Yunxiang Huang (7535135)

“…The trajectories of depression from baseline to 1-year follow-up were categorized into four groups: never (PHQ-9 < 10 at two time points), new-onset (PHQ-9 < 10 at baseline & PHQ-9 ≥ 10 at follow-up), recovered (PHQ-9 ≥ 10 at baseline & PHQ-9 < 10 at follow-up) and persistent depression (PHQ-9 ≥ 10 at two time points). …”

Temporal Trends of Great Lakes Legacy Contaminants: Ecological and Biological Considerations Applying the Age-Trend Model by James J. Pagano (2043490)

“…Our research revealed that select legacy contaminant groups (∑PCBs, ∑DDTs, ∑chlordanes, and ∑5PBDEs) have similar <i>t</i>_1/2 and <i>k</i>₂ values across the Great Lakes, with the exception of both Lake Erie sites and the Lake SuperiorKeweenaw Point site. …”

Efficacy of inhibition depends on spatial and temporal features of GABA_AR input. by Nicolas Doyon (344567)

“…Note that this is the optimal frequency for activation of a single “test” synapse; optimal input frequency would necessarily decrease as the number of activated synapses increased, although the exact relationship would depend on the spatial distribution of those active synapses (see <b>A</b>) as well as the level of background synaptic activity.…”

Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay by Blake A Rowe (19589318)

“…</p> <p><b>Results & conclusion:</b> A larger dynamic range, high inhibition and higher drug tolerance were achieved by adding an acid dissociation step to the assay, performing atypical biotin labeling of Drug 1 and switching to a detection target that contained an Fc linker to increase steric hinderance and decrease its binding affinity to Drug 1.…”

The impact of fishing on a highly vulnerable ecosystem, the case of Juan Fernández Ridge ecosystem - Fig 7 by Javier Porobic (6392612)

“…Note that the y-axes is the ratio of change against the starting conditions—so a -0.5 result indicates a 50% decrease and a 0.5 result indicates a 50% increase -.…”

Simulating non-small cell lung cancer with a multiscale agent-based model-2 by Zhihui Wang (88248)

“…<p><b>Copyright information:</b></p><p>Taken from "Simulating non-small cell lung cancer with a multiscale agent-based model"</p><p>http://www.tbiomed.com/content/4/1/50</p><p>Theoretical Biology & Medical Modelling 2007;4():50-50.…”

Efficacy of SGLT2 inhibitors for anthracycline-induced cardiotoxicity: a meta-analysis in cancer patients by Sana Mohsin (19773969)

“…</p> <p><b>Results:</b> 3 cohort studies were identified, analyzing 2817 patients. Results display a significant reduction in overall mortality [RR = 0.52 (0.33–0.82); <i>p</i> = 0.005; I²= 32%], HF hospitalization [RR = 0.20 (0.04–1.02); <i>p</i> = 0.05; I²= 0%] and no significant reduction in HF incidence [RR = 0.50 (0.20–1.16); <i>p</i> = 0.11, I²= 0%].…”

A role for <i>bmm</i> function in neurons in the regulation of whole-body triglyceride breakdown in males. by Lianna W. Wat (8339454)

“…(B) There was a significant reduction in whole-body triglyceride levels in 5-day-old <i>elav>+</i> and <i>+>UAS-bmm-RNAi</i> control males between 0 and 12 hours STV (<i>p</i> = 1 × 10⁻⁵ and 9 × 10⁻⁶, respectively; one-way ANOVA followed by Tukey HSD test); however, no significant decrease in triglyceride levels was observed between 0 and 12 hours STV in <i>elav>UAS-bmm-RNAi</i> males (<i>p</i> = 0.13; one-way ANOVA followed by Tukey HSD test). …”

The Efficacy of Hyperbaric Oxygen Therapy on Middle Cerebral Artery Occlusion in Animal Studies: A Meta-Analysis by Yang Xu (178421)

“…Subgroup analysis showed that a maximal neuro-protective effect was reached when HBO was administered immediately after MCAO with an absolute atmospheric pressure (ATA) of 2.0 (50% decrease; 95% CI, 43% -57% decrease; <i>p</i> < 0.0001) and more than 6 hours HBO treatment (53% decrease; 95% CI, 41% -64% decrease; <i>p</i> = 0.0005).…”