Image_2_Molecular mechanisms regulating natural menopause in the female ovary: a study based on transcriptomic data.jpeg by Quan Liu (486219)

“…Increased contents of terminally differentiated HMGB1+ Granulosa and GSTA1+ Granulosa were observed in the ovaries of individuals aged 50-69. Signaling pathway activity analysis indicated a gradual decrease in TGFb and MAPK pathway activity with menopause progression, while p53 pathway activity increased. …”

A reduction in brain mass and cortical volume seen in the adult <i>Cln6^nclf</i> mouse. by Jeremy P. Morgan (479017)

Effect of AQHAR on hnRNP-K and mortalin, tumor metastasis mediating proteins, in A549 and U2OS cells. by Kejuan Li (2580184)

Overexpression of Rab26 restricts insulin secretion in β-cells. by Ruijuan Zhuang (3938915)

Table 1_A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-b... by Huaqu Zeng (20601563)

“…</p>Method<p>A total of 22 patients with brain metastases were retrospectively enrolled. …”

Divergent signalling pathways mediate the effects of Aβ on Homer1b and Shank1 cluster dispersal. by Francesco Roselli (211670)

“…Wort+Aβ and Wort alone; p<0.05). Notably, wortmannin itself decreased Shank1 (but not Homer1b) cluster size (74.3±10.3%, cf. …”

Behavioral classification of animals with the FULL and ECO models. by Naëmi Kuehn (17310359)

“…N = 7 control and n = 5 KA animals.</p>…”

Joule heating of the brain tissue during the application of pulsed electric fields for e-biopsy. by Ilai Genish (12569114)

“…Panels <b>a-c</b> show the simulation for high voltage, short-duration protocol: 40 pulses 1000 V, 40 μs, 4 Hz, coupled with the simulation for low voltage, long-duration protocol: 40 pulses 50 V, 15 ms, delivered at 4 Hz. …”

Assessing the benefits of five years of different approaches to treatment of urogenital schistosomiasis: A SCORE project in Northern Mozambique by Anna E. Phillips (4050331)

“…<i>haematobium</i> was seen in adults even in the SBT arms implying the rate of transmission in the community had been decreased, even where only school children have been treated, which has significant logistical and cost-saving implications for a national control programme in justifying CWT.…”

image2_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

Table_1_Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review.pdf by Martine Bellanger (4101313)

“…The median cost-effectiveness ratio (in 2018 USD) was $24,973, and 80% of the interventions had a ratio below the $50,000 threshold. The low-fat-diet program for postmenopausal women was cost-effective at a societal level, and the physical activity interventions, such as the Be Active Program in the UK, had the best cost saving results. …”

Table_3_Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review.pdf by Martine Bellanger (4101313)

“…The median cost-effectiveness ratio (in 2018 USD) was $24,973, and 80% of the interventions had a ratio below the $50,000 threshold. The low-fat-diet program for postmenopausal women was cost-effective at a societal level, and the physical activity interventions, such as the Be Active Program in the UK, had the best cost saving results. …”

image2_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

Complement to Fig 7—A p53-dependent response promotes tissue development when nuclear reassembly is compromised. by Jingjing Li (7654)

“…Wings discs of indicated genotypes were incubated with EdU for 1 h and then co-stained for DNA (DAPI) and cleaved Dcp-1. Scale bar: 50 μm. Coordinate values used to generate graphs are available in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002780#pbio.3002780.s016" target="_blank">S1 Data</a>.…”

image1_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

image1_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

Changes in pain following bilateral intermittent theta-burst, transcranial magnetic stimulation for depression: A retrospective chart review by Sawmmiya Kirupaharan (18144475)

“…Of the 32 patients with both pre- and posttreatment pain scores, there was a significant decrease from 40.0 (IQR = 5.5–71.8) to 15.0 (IQR = 3.5–53.8; <i>P</i> = 0.037). …”

Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever by Michelle Mendenhall (201521)

“…Antiviral activity and reduced disease severity was evidenced by dramatic reductions in peak serum virus titers and AST concentrations in favipiravir-treated animals. Moreover, a sharp decrease in body temperature was observed shortly after the start of treatment. …”

Table_2_Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review.pdf by Martine Bellanger (4101313)

“…The median cost-effectiveness ratio (in 2018 USD) was $24,973, and 80% of the interventions had a ratio below the $50,000 threshold. The low-fat-diet program for postmenopausal women was cost-effective at a societal level, and the physical activity interventions, such as the Be Active Program in the UK, had the best cost saving results. …”

Table2_A multicenter clinical study on parent-implemented early intervention for children with global developmental delay.pdf by Ping Dong (627021)

“…Furthermore, there was a significant decrease in the mean standard score of dysfunctional interaction, difficult children and the total level of parental stress in the term test for the experimental groups (P < 0.001 for all).…”