DataSheet_1_A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage.pdf by Manfred Fliegauf (391677)

“…The missense change disabled processing of the precursor to prevent the generation of mutant p50. Unlike the wildtype p50, the overexpressed mutant p50-Tyr350Cys was also not sustainable and showed a conspicuous subnuclear mislocalization with accumulation in dense aggregates instead of a homogenous distribution. …”

Deep neural network reliably determines the emitter's sex from individual vocalizations. by A. Ivanenko (9010331)

“…Correspondingly the change in the network's weights (light red) progressively decreased after stabilizing after ~6k iterations. Data shown for a representative training run. …”

Scaled, pairwise relative Weighted Interval Score (rWIS) (see <i>Methods</i> for description) by spatial scale for sets of team forecasts that submitted forecasts for the US nation... by Velma K. Lopez (18510171)

Bone-related serum chemistry endpoints: Aquamin (180-day treatment group) versus placebo. by Muhammad N. Aslam (6598001)

Fig 1 - by Velma K. Lopez (18510171)

Podocyte numbers in control and iPLA₂γ KO mice (WT1-positive cells). by Andrey V. Cybulsky (4007012)

Changes in Microbial Communities, Including both Uncultured and Culturable Bacteria, with Mid-Ocean Ballast-Water Exchange during a Voyage from Japan to Australia by Akiko Tomaru (511024)

Reply to Jüni and colleagues regarding “Converting standardized mean differences to dichotomous outcomes: A comment on the Cochrane review ‘Intra-articular corticosteroid for knee... by Martin Mayer (6509486)

“…As I noted previously, I submit the following in a spirit of collegial collaboration.</p> <p> </p> <p>They agree with my first point regarding the assumed probability of achieving ≥50% improvement in function in the control group, and they provide a corrected probability in line with my previous correspondence (i.e., they correct the probability from 26% as they used previously[1,3,5–7] to 22% as noted in my previous correspondence[2,4]). …”

Impact of water column attenuation on achromatic contrast (Δ<i>S</i>_<i>AC</i>) to fish (A) and bird (B) models. by Brandon J. Russell (793587)

“…Dashed line represents a ratio of 1 (no change). Decrease in achromatic contrast was generally low, except for the avian predator under the 5 m conditions, where median Δ<i>S</i>_<i>AC</i> of both species decreased by 15% and up to 50% for some individuals. …”

Locating dopamine receptors several microns away from the dopamine release site produces only a small change in cAMP signaling. by Rodrigo F. Oliveira (184716)

“…<p>A spatial gradient of dopamine decreases (A) cAMP and PKA activity as measured by (B) phosphoThr34 DARPP-32 and (C) phosphoSer845 GluA1, but no delay in time course. …”

Table_1_The Rapid Population Collapse of a Key Marine Predator in the Northern Antarctic Peninsula Endangers Genetic Diversity and Resilience to Climate Change.docx by Douglas J. Krause (4630831)

“…To update the population status of SSI AFS, we analyzed 20 years of field-based data including population counts, body size and condition, natality, recruitment, foraging behaviors, return rates, and pup mortality at the largest SSI colony. Our findings show a precipitous decline in AFS abundance (86% decrease since 2007), likely driven by leopard seal predation (increasing since 2001, p << 0.001) and potentially worsening summer foraging conditions. …”

Human F₁F₀ ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter? by Johann Habersetzer (385365)

“…We report here that in mammalian cells in culture, the shRNA-mediated down-regulation of subunits <i>e</i> and <i>g</i> affects the stability of ATP synthase and results in a 50% decrease of the available functional enzyme. …”

Table_2_The Rapid Population Collapse of a Key Marine Predator in the Northern Antarctic Peninsula Endangers Genetic Diversity and Resilience to Climate Change.csv by Douglas J. Krause (4630831)

“…To update the population status of SSI AFS, we analyzed 20 years of field-based data including population counts, body size and condition, natality, recruitment, foraging behaviors, return rates, and pup mortality at the largest SSI colony. Our findings show a precipitous decline in AFS abundance (86% decrease since 2007), likely driven by leopard seal predation (increasing since 2001, p << 0.001) and potentially worsening summer foraging conditions. …”

Germination Ecology of Ivy-Leaved Morning-Glory: an Invasive Weed in Soybean Fields, Iran by A. SIAHMARGUEE (8743458)

“…Acidity was a limiting factor for the germination, due to inhibiting effect of alkaline conditions on germination. …”

DataSheet1_The inviscid incompressible limit of Kelvin–Helmholtz instability for plasmas.PDF by A. Briard (18408375)

Germination Ecology of Catchfly (Silene conoidea) Seeds of Different Colors by A. TANVEER (4646011)

“…Optimum germination of seeds of all colors was recorded at a temperature of 15 oC. Germination of catchfly seeds of all colors followed decreasing trend as NaCl concentration increased from 50 mM to 200 mM. …”

Functional effects of 10E8 on HIV-1 clade C variants including those with a naturally occurring L673 residue. by Arthur S. Kim (603570)

“…<p>(<b>A</b>) Partial neutralization by 10E8 of clade C isolates TM20.13 and M20490 BMR 211 using the TZM-bl assay. …”

Supplementary Material for: Respiratory Sinus Arrhythmia Attenuation via Targeted Lung Denervation in Sheep and Humans by Valipour A. (6859757)

“…The average treatment location was more distal in the remaining 2 animals, which did not exhibit RSA attenuation, suggesting diminished denervation. HF power decreased in 5 of 6 humans, with 3 subjects reaching less than 50% of their baseline HF power 90 days after TLD. …”

Table_1_Erenumab for Migraine Prevention in a 1-Year Compassionate Use Program: Efficacy, Tolerability, and Differences Between Clinical Phenotypes.DOCX by Jean Schoenen (61359)

“…The lower efficacy in CM than in EM was mainly due to a very low 50% responder rate in patients with CM with continuous pain (13%) as compared to CM with pain-free periods (58%) (p < 0.001). …”

Specific and general adaptations following motor imagery practice focused on muscle strength in total knee arthroplasty rehabilitation: A randomized controlled trial by Armin H. Paravlic (7244804)

“…</p><p>Results</p><p>Significant differences in treatment effects were observed for the MIp group compared to CON: the MIp showed less strength decrease (ES = 1.15, 95% CI: 0.32, 1.99, p = 0.022); faster self-selected speed under single (ES = 2.12, 95% CI: 1.16, 3.08, p = 0.001) and dual task (ES = 1.59, large, 95% CI: 0.67, 2.50, p = 0.002) conditions; brisk-pace gait speed during single (ES = 1.32, 95% CI: 0.47, 2.17, p = 0.020) and dual task conditions (ES = 1.31, large, 95% CI: 0.38, 2.23, p = 0.013); improved chair sit-to-stand (ES = 1.45, large, 95% CI: 0.58, 2.31, p = 0.004) performance; and a higher score on MI ability questionnaires for kinaesthetic imagery (KI) (ES = 0.55, 95% CI: -0.23, 1.34, p = 0.010) and internal visual imagery (EVI) (ES = 0.99, 95% CI: 0.18, 1.80, p = 0.039) scales, respectively. …”