Chemoenzymatic Approach for the Proteomics Analysis of Mucin-Type Core‑1 O‑Glycosylation in Human Serum by Xin You (784189)

“…Human serum is a complex body fluid that contains various N-linked and O-linked glycoproteins. …”

Chemoenzymatic Approach for the Proteomics Analysis of Mucin-Type Core‑1 O‑Glycosylation in Human Serum by Xin You (784189)

“…Human serum is a complex body fluid that contains various N-linked and O-linked glycoproteins. …”

SILD increases renal expression of TEMs pro-angiogenic macrophages. by Mary Anna Venneri (737094)

Recursive Feature Addition (RFA) process and Cross-Validations (CV) used in procedures 3 to 5. by Jessica Schrouff (168128)

REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis by Rodrick Montjean (400649)

“…The effect of REG-O3, solubilized in a liposomal solution and injected at either 5, 25 or 50 μg/50 μL, was compared to liposomal (LIP), dexamethasone and hyaluronic acid (HA) solutions. …”

IDN5706 inhibits proteolytic processing of APP to CTFs, and production of Aβ species. by Viviana A. Cavieres (500139)

IDN5706 reduces the levels of EDEM1 in a time-dependent manner. by Viviana A. Cavieres (500139)

Efficacy and Acceptability of Glycemic Control of Glucagon-Like Peptide-1 Receptor Agonists among Type 2 Diabetes: A Systematic Review and Network Meta-Analysis by Zhixia Li (2736331)

“…Dulaglutide, exenatide long-acting release (exe_lar), liraglutide and taspoglutide had significant lowering effect when compared with sitagliptin (HbA1c<7.0%) and insulin (HbA1c<6.5%). Finally, according to SUCRAs, placebo, thiazolidinediones and albiglutide had the best decrease effect on hypoglycemia; sulphanylureas, sitagliptin and insulin decrease the incidence of treatment discontinuation most; exe_lar and dulaglutide had the highest impact on glycemic level among 13 treatments.…”

Apoptosis is enhanced in DCE- or CS-treated keratinocytes. by Claudia Scarponi (205759)

Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC. by Marcus Hollenbach (376231)

“…Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”

Effects of 20 μM 5-aza-dC Treatment on the 10q25 Neocentromere by Nicholas C Wong (14627)

“…Six CpG islets (28, 31, 69, 70, 71, and 101) showed an increase in DNA methylation upon the formation of the 10q25 neocentromere. However, following 5-aza-dC treatment, the methylation level of these CpG islets decreased significantly. …”

Hel2 and Asc1 attenuate gene expression from stall-containing mRNAs only at high initiation rates. by Heungwon Park (3859507)

LM11A-31's effect on cholinergic dystrophic neurites in cortex of mid-stage APP^L/S mice. by Danielle A. Simmons (621167)

“…Scale bar in photomicrograph A = 50 µm. Quantitative analysis showed that LM11A-31 decreases the total area occupied by the clusters (<b><i>C</i></b>) by decreasing their number (<b><i>D</i></b>) but not the mean area per cluster (<b><i>E</i></b>). …”

Representative data from primary HTS. by Pamela Y. Ting (713174)

Working model for REG-O3 mechanism of action. by Rodrick Montjean (400649)

Effects of COS on the expression of MCP-1 and iNOS mRNA in RGC-5 cells. by I-Mo Fang (470460)

“…<p>RGC-5 cells were stimulated with 0.5mM PQ and then treated with 50 μg/ml (low-dose) or 100 μg/ml (high-dose) COS for 12 hours. …”

Plot of adjusted risk ratios of high SARS-CoV-2 viral load upon presentation to the emergency department for each study day compared to the first day of the study that includes an... by Michael J. Satlin (9160569)

Sensitivity of U251 stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…<p>U251, U251-pCMV-HSVtk, and U251-pGFAP-HSVtk cells were treated with 0, 1, 5, or10 μg/ml of GCV for 5 days. (A–D) Live-cell phase images of U251 parent cells displayed no cytotoxicity up to 10 μg/ml of GCV. …”

Expression of Glo-I and MGO in whole rat liver. by Marcus Hollenbach (376231)

3D spheroids enhance NFAT3 and CXCR4 expression. by Keven Huang (675616)

“…(<b>C</b>) Corresponding to the increase in NFAT3 in 3D spheroids, real-time PCR showed a 30-50-fold increase in CXCR4 mRNA in 3D spheroids when compared to adherent HeyA8 cells. (*, P <0.05 vs Adh, 1-way ANOVA). …”