Demonstration that SP-1 and SP-3 negatively regulates the PP2A-Aα promoter. by He-Ge Chen (90952)

“…Expression of the exogenous pCMV-SP-1 in both types of ocular cells attenuated expression of the endogenous gene coding for PP2A-Aα. F. Expression of the exogenous SP-3 in both types of ocular cells induced only slight decrease in the luciferase reporter gene activity within 0 to 500 ng of the pCMV-SP-3 plasmid, which is not statistically significant. …”

Image5_Effectiveness and safety of brucea javanica oil assisted TACE versus TACE in the treatment of liver cancer: a systematic review and meta-analysis of randomized controlled tr... by Zhi-Hai Wu (13197603)

Simultaneous Hypoxia and Low Extracellular pH Suppress Overall Metabolic Rate and Protein Synthesis In Vitro by Brita Singers Sørensen (783581)

“…A dramatic decrease in ATP turnover (SiHa) and protein synthesis (both cell lines) was observed when hypoxia and low pH_e were combined.…”

Meta-Analysis: Effects of Probiotic Supplementation on Lipid Profiles in Normal to Mildly Hypercholesterolemic Individuals by Mikiko Shimizu (205878)

“…Probiotic interventions (including fermented milk products and probiotics) produced changes in total cholesterol (TC) (mean difference –0.17 mmol/L, 95% CI: –0.27 to –0.07 mmol/L) and low-density lipoprotein cholesterol (LDL-C) (mean difference –0.22 mmol/L, 95% CI: –0.30 to –0.13 mmol/L). …”

Table 5_Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic... by Weifeng Zhen (12969341)

“…Ultra-protective ventilation (≤4 mL/kg predicted body weight) has the potential to further decrease ventilator-induced lung injury but may result in severe hypercapnia. …”

CA alleviated DOX-induced myocardial injury <i>in vitro</i> and <i>in vivo</i>. by Meijiao Mao (10677555)

IGF-1 induces an increase in <i>PRNP</i> expression through the PI3K-Akt-FOXO3a pathway. by Ting Liu (45625)

“…(C) and (D) Western blotting showing the relationship between the phosphorylation of FOXO3a and <i>PRNP</i> expression. Treatment with 50 and 100 ng/ml IGF-1 remarkably increased the phosphorylation of FOXO3a in both the SH-SY5Y and HeLa cell lines but caused little variation in the total level of FOXO3a. …”

Meta-analyses of the association of <i>G6PC2</i> allele variants with elevated fasting glucose and type 2 diabetes by Yuanyuan Shi (563992)

“…Per increment of G allele at rs560887 and A allele at rs573225 resulted in a FG 0.070 mmol/l and 0.075 mmol/l higher (ß (95% CI) = 0.070 (0.060, 0.079), <i>p</i> = 4.635e-50 and 0.075 (0.065, 0.085), <i>p</i> = 5.856e-48, respectively). …”

P2RX7 is overexpressed in metastatic ovarian carcinoma tumors. by José David Nuñez-Ríos (18823719)

DataSheet_5_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…The number of stings ranged from 7 to > 2,000, with a median of 52.5. Symptoms of envenoming were classified as mild, moderate, or severe in 80% (16), 15% (3), and 5% (1) of patients, respectively; patients with mild, moderate, or severe envenoming received 2, 6, and 10 vials of AAV as per the protocol. …”

DataSheet_5_Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.docx by Alexandre Naime Barbosa (4830609)

“…The number of stings ranged from 7 to > 2,000, with a median of 52.5. Symptoms of envenoming were classified as mild, moderate, or severe in 80% (16), 15% (3), and 5% (1) of patients, respectively; patients with mild, moderate, or severe envenoming received 2, 6, and 10 vials of AAV as per the protocol. …”

Table_1_Is a Higher Protein-Lower Glycemic Index Diet More Nutritious Than a Conventional Diet? A PREVIEW Sub-study.pdf by Alice Meroni (9737102)

“…term=NCT01777893&draw=2&rank=1) who were randomly assigned to a HPLG diet (25% energy from protein, dietary GI ≤ 50, n = 85) or a MPMG diet (15% energy from protein, dietary GI ≥ 56, n = 76). …”

Baseline characteristics of study subjects. by Arlete Gianfaldoni (17655603)

“…To detect LH and FSH pulses, the technique proposed by Santen and Bardin was adopted; therefore, one pulse was defined as a 20% increase in the concentrations as to the preceding point, followed by an important decrease.…”

S1 File - by Arlete Gianfaldoni (17655603)

“…To detect LH and FSH pulses, the technique proposed by Santen and Bardin was adopted; therefore, one pulse was defined as a 20% increase in the concentrations as to the preceding point, followed by an important decrease.…”

Hourly cumulative frequency of LH and FSH pulses. by Arlete Gianfaldoni (17655603)

“…To detect LH and FSH pulses, the technique proposed by Santen and Bardin was adopted; therefore, one pulse was defined as a 20% increase in the concentrations as to the preceding point, followed by an important decrease.…”

Metformin induced inhibition of HaCaT cells proliferation. by Fatima Ochoa-Gonzalez (2559499)

MmuPV1 integration, host gene expression, and cell growth. by Lulu Yu (737362)

“…<b>B and C,</b> Expression of MmuPV1 E6E7 (green) correlates with a decrease in the expression of mouse Krt10 and Fabp5 (red) in the tail tumor tissues of FoxN1^nu/nu at day 21 as measured by RNA ISH using dual immunofluorescence RNAscope analysis. …”

Reducing AHP duration in mice with upregulated astroglial Cx30 restores pyramidal cell excitability and excitatory synaptic transmission. by Eléonore Hardy (15208385)

Study sample. by Nipaporn Butsing (19470003)

“…</p><p>Results</p><p>Of the participants, 62.6% were men, and the mean age was 64.0 (SD = 12.5). The median mRS scores ranged from 3.0 at discharge to 0.0 at six months post-discharge. …”

Table1_Longitudinal Trend of Plasma Concentrations of Extracellular Vesicles in Patients Hospitalized for COVID-19.DOCX by Elena Campello (11953730)

“…The following EVs were measured: endothelium-, platelet-, leukocyte-derived, bearing tissue factor (TF)+, angiotensin-converting enzyme (ACE2)+, platelet-derived growth factor receptor-β (PDGF-β)+ and SARS-CoV-2-nucleoprotein (NP)+. 91 patients were recruited for baseline EV analysis (mean age 67 ± 14 years, 50.5% male) and 48 underwent the longitudinal evaluation. …”