Human vessel formation after progenitor co-transplantation depends on hypoxia-induced factors in MSPCs but not ECFCs. by Nicole A. Hofmann (138477)

“…Human mesodermal origin was visualized with anti-human vimentin monoclonal antibody staining (h.Vimentin, brown; mouse and human nuclei counterstained with hematoxylin, blue; third row; scale bar 50 µm). Plugs contain different numbers of h.Vimentin-negative infiltrating mouse CD45⁺ hematopoietic cells (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044468#pone.0044468.s006" target="_blank">Figure S6C</a>). …”

<i>NOTCH3</i> Variants and Risk of Ischemic Stroke by Owen A. Ross (139522)

“…</p> <p>Results</p><p>Sequencing of the 269 SWISS probands identified one (0.4%) with small vessel type stroke carrying a known CADASIL mutation (p.R558C; Exon 11). Of the 19 common <i>NOTCH3</i> variants identified, the only variant significantly associated with ischemic stroke after multiple testing adjustment was p.R1560P (rs78501403; Exon 25) in the combined SWISS and ISGS Caucasian series (Odds Ratio [OR] 0.50, P=0.0022) where presence of the minor allele was protective against ischemic stroke. …”

Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection. by Olga A. Maximova (3115716)

“…Note: (i) pial lymphocytic infiltration (yellow arrows) appeared at 7 dpi (<b>G</b>), increased at 14 dpi (<b>H</b>), and decreased at 21 dpi (returning to the level seen at 7 dpi) (<b>I</b>); (ii) a rare focal lesion (red asterisk in H) with depleted MAP2-IR in the Purkinje cell layer (PCL), granule cell layer (GrCL) neurons, and partially in the molecular layer (ML) is spatially associated with the increased pial lymphocytic infiltration. …”

Coordinated polarity induced by high flow triggers vessel regression. by Claudio A. Franco (124909)

“…Scale bars (<b>A</b>: 50 μm; <b>E</b>: 20 μm). The data used to make this figure can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002125#pbio.1002125.s001" target="_blank">S1 Data</a>.…”

Simplified depiction of hyperthermia impacts on the intrafollicular complement and coagulation cascade. by Louisa A. Rispoli (8201232)

“…Alpha-2-Macroglobulin (A2M) is an anti-proteinase that complexes with proteinases such as kallikrein [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0227095#pone.0227095.ref050" target="_blank">50</a>] to inhibit proteolytic activity.…”

Data_Sheet_1_Assessing the Impact of Ih Conductance on Cross-Frequency Coupling in Model Pyramidal Neurons.docx by Melvin A. Felton (9358796)

Table_1_COVID-19 Era Effect on Pandemic and Post-pandemic Pediatric Telemedicine Use: A Survey of the European Academy of Pediatrics Research in Ambulatory Settings Network.XLSX by Stephen M. Reingold (11596360)

“…Little is known about what we can expect after the pandemic: if physicians will opt for telemedicine modalities and if tele-pediatrics will continue to be a significant mode of community pediatric care.…”

DataSheet1_Conservation status and historical relatedness of South African communal indigenous goat populations using a genome-wide single-nucleotide polymorphism marker.docx by T. C. Chokoe (13217025)

“…The use of Illumina goat SNP50K BeadChip shows that there was a migration route of communal indigenous goat populations from the northern part (LP) of South Africa to the eastern areas of the KZN that confirmed their historical relatedness and coincides with the migration periods of the Bantu nation.…”

Table_1_The beneficial effect of sulforaphane on platelet responsiveness during caloric load: a single-intake, double-blind, placebo-controlled, crossover trial in healthy particip... by Hidde P. van Steenwijk (16499940)

“…Participants carrying the polymorphic variant NAD(P)H dehydrogenase quinone 1 (NQO1*2) showed decreased excretion of sulforaphane (p = 0.035).</p>Conclusion<p>Sulforaphane was shown to be effective in targeting platelet responsiveness after a single intake. …”

In Patients with Established RA, Positive Effects of a Randomised Three Month WBV Therapy Intervention on Functional Ability, Bone Mineral Density and Fatigue Are Sustained for up... by Alessandra Prioreschi (2609719)

“…Hip BMD was significantly reduced in the CON group (0.97(0.05) to 0.84(0.05) g.cm^-2, p = 0.01), while no decreases were seen in the WBV group (1.01(0.05) to 0.94(0.05) g.cm^-2, p = 0.50). …”

Image_1_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.tif by Mengting Chen (1419172)

“…Moreover, the JK5G group had a lower incidence of anemia (63.33% vs. 13.33%, p < 0.001), decreased lymphocyte count (20.00% vs. 0%, p = 0.010), decreased appetite (53.33% vs. 16.67%, p = 0.003), nausea (33.33% vs. 6.67%, p = 0.010), and asthenia (30.00% vs. 6.67%, p = 0.017) than the control group. …”

Image_2_JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China.tif by Mengting Chen (1419172)

“…Moreover, the JK5G group had a lower incidence of anemia (63.33% vs. 13.33%, p < 0.001), decreased lymphocyte count (20.00% vs. 0%, p = 0.010), decreased appetite (53.33% vs. 16.67%, p = 0.003), nausea (33.33% vs. 6.67%, p = 0.010), and asthenia (30.00% vs. 6.67%, p = 0.017) than the control group. …”

Comprehensive Evaluation and Implementation of Improvement Actions in Butcher Shops by Gerardo A. Leotta (3115335)

“…<div><p>Foodborne pathogens can cause acute and chronic diseases and produce a wide range of symptoms. Since the consumption of ground beef is a risk factor for infections with some bacterial pathogens, we performed a comprehensive evaluation of butcher shops, implemented improvement actions for both butcher shops and consumers, and verified the impact of those actions implemented. …”

CD14⁺ monocytes inhibit IFN-α production triggered by Ab-RSV via TLR7 in pDC. by Marcel A. Schijf (461275)

“…<p>(<b>A</b>) IFN-α production in CD14⁺ cell depleted PBMCs induced by Ab-RSV complexes, TLR9 ligand ODN 2216 and TLR7 ligand imiquimod is decreased by blocking endosomal acidification with 50nM Bafilomycin A₁. …”

Identification of the class of mediators present in the hvKP1 generated conditioned minimal medium and ascites that enhance the growth and/or survival of hvKP1. by Thomas A. Russo (188770)

“…<p>The growth of hvKP1 was assessed at 0, 3, 6, and 24 hours in human ascites (batch 1). <u>Panel A</u>: Ascites was not supplemented (unconditioned) or supplemented with: 1) 5% hvKP1-generated conditioned (cond) ascites (batch 1) or 2) 50% conditioned ascites generated from the <i>E. coli</i> laboratory strain BW25113 and isogenic derivatives deficient in the production of enterobactin (BW25113Δ<i>entB</i> (CGSC#8704), BW25113Δ<i>entC</i> (CGSC#8702)), AI-2 molecules (BW25113Δ<i>luxS</i> (CGSC#10100)), and indole (BW25113Δ<i>tnaA</i> (CGSC#8309)) (batch 1). …”

Photothermal therapy co-localized with CD137 agonism improves survival in an SM1 melanoma model without hepatotoxicity by Jacob A Medina (19530945)

“…<i>In vivo</i>, SM1 tumor-bearing mice treated with αCD137-PBNP-PTT exhibited a significantly higher survival rate (50%) without hepatotoxicity, compared with control treatments.…”

Table1_40Ar/39Ar ages and geochemistry of the Intersalar Range of the Bolivian Altiplano: A volcanological transect spanning the arc and reararc of the Central Andean Plateau.xlsx by Morgan J. Salisbury (13896744)

“…Nb concentrations show the strongest correlation with distance into the reararc compared to all other trace elements (arc Nb = 6–16 ppm; reararc Nb = 12–26 ppm). Nb/Nb* values (a measurement of the depth of the negative Nb anomaly) correspondingly increase into the reararc (indicating smaller anomalies), reaching a maximum at Coracora volcano before decreasing in the far rear arc region. …”

Data_Sheet_1_Trends in rates and causes of hospitalization among people living with HIV in the antiretroviral therapy era: A retrospective cohort study in China, 2008–2020.docx by Ying Liu (18461)

“…Older age, non-men who have sex with men transmission, late presenters, HIV viral load (VL) > 50 copies/mL, and CD4 counts ≤ 200 cells/μL were associated with a higher hospitalization risk (all P < 0.05).…”

Table1_A disproportionality analysis of low molecular weight heparin in the overall population and in pregnancy women using the FDA adverse event reporting system (FAERS) database.... by Huanying Xu (17813399)

“…However, despite the widespread use of LMWH in clinical indications, its adverse events (AEs) have not received substantial attention, and there is a lack of systematic and comprehensive AE studies. …”

Table_1_Trends in outpatient and inpatient visits for separate ambulatory-care-sensitive conditions during the first year of the COVID-19 pandemic: a province-based study.DOCX by Tetyana Kendzerska (519437)

“…CHF-related hospitalizations also decreased, albeit to a lesser extent. For angina, hypertension, diabetes, and epilepsy, hospitalization rates reduced initially, but returned to pre-pandemic levels by the end of the year.…”