VER-155008 abrogated viral protein synthesis pre-translationally in TREx BCBL1-RTA cells. by Belinda Baquero-Pérez (706834)

“…(C) Immunoblot analysis showing that reactivated cells treated with non-cytotoxic inhibitor concentrations (1 to 2.5 μM) for 24 h revealed a decrease in viral proteins compared with DMSO-treated samples while cellular proteins remained unaffected. …”

Lagged biodiversity recoveries. by Roberto Latorre (282007)

“…Notably, the figure illustrates cases where biodiversity loss is driven by reduced speciation rather than increased extinction (e.g., the event indicated by the arrow, where a prior burst of speciation reaching nearly 50% is followed by a sharp drop in speciation, while extinction rates remain nearly constant or even decrease). …”

Physiological and transcriptomic data for <i>sdc</i>, <i>dc</i> and <i>sdc/dc</i> mutants. by Diego H. Sanchez (230286)

“…Right: Relative mean aerial biomass as percentage of controls obtained from the data shown on the left, denoting a decrease of at least 30% in relative biomass after treatment of genetic backgrounds harboring the <i>sdc</i> mutation. …”

Spatial-temporal variation in litterfall in seasonally dry tropical forests in Northeastern Brazil by V. F. P. Araújo (7141901)

“…The inter- and intra-annual variation in litterfall production was positively correlated with precipitation and evapotranspiration rates, and four months after the highest precipitation rates, there was a marked decrease in litterfall occurred during the dry season. …”

Expression of MP does not interfere with the silencing pathway. by Hannes Vogler (272256)

“…In the presence of MP, the GFP siRNA levels are reduced by about 50% compared to the empty vector control, whereas dMP causes a slight increase. …”

DataSheet_2_Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis.xlsx by Marlene Jara (774474)

“…</p>Results and discussion<p>We demonstrated in vitro that a variable proportion of cells remained viable, showing all the criteria of DT and not of DR: i) signatures of quiescence, under drug pressure: reduced proliferation and significant decrease of rDNA transcription; ii) reversibility of the phenotype: return to low IC₅₀ after removal of drug pressure; and iii) absence of significant genetic differences between exposed and unexposed lineages of each strain and absence of reported markers of DR. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…Three heavily treated relapsed/refractory AML patients with FLT3-ITD were treated with TP-0903 50 mg daily, on a phase 1b/2 clinical trial, for as long as disease response or clinical benefit was observed. …”

Effect of rotenone on the striatum, VTA, and SNc TH immunoreactivity. by Nian Xiong (218611)

“…The TH immunoreactivity on the ipsilateral side of the striatum was decreased by 66.4% (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007878#pone-0007878-g004" target="_blank">Figure 4I–J</a>; *P<0.05, as compared to the contralateral side). …”

Image_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.TIF by Gavin J. B. Elias (12044813)

“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”

Data_Sheet_1_Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.docx by Lei Yuan (713591)

“…After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. …”

Antibodies of the PGT121 family compete with sCD4, but not PGV04, for binding to gp120 in solution and on the cell-surface. by Jean-Philippe Julien (135641)

Schematic representation of the TRA/TRD locus use. by Florence Thuderoz (366862)

“…<p>The scheme shows the rearrangement distribution of 4 V genes with all J genes. The dashed red arrow indicates the decreasing frequency of rearrangements which correlates with the associations of distal V and J genes. …”

Fitness of the ligases and their relationships in crude evolutionary time. by Carolina Díaz Arenas (504034)

“…Populations where poly-A mutants (<i>e.g</i>., A27) are present in high frequency decrease in size, and are at risk of extinction, due to the low mean fitness value of the population, which keeps decreasing as adenylation tracks are extended. …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)

CTR-C PDZ- binding motif mutation and TJ disruption and invasion. by Ahmed Aljameeli (2548528)

“…<p>A. Transepithelial Electric Resistance (TER): Polarized PC-3v, PC-3-CTRwt and PC-3CTR-∆ESS cells were serum-starved for 4 hours, then treated with/without 50 nM CT. …”

Gap detection with the AT1 model. by Javier Estrada (243042)

“…<p><b>(A)</b> Plots of cytoplasmic Ca²⁺ for three representative cells in three experiments in which a step increase in histamine was interrupted by two (expt. 21 & 23) or five (expt. 22) gaps, with the size of the gap changing between experiments as shown. …”

Metabolic parameters and beta activity during infusion of human insulin, insulin detemir and saline in 10 overweight individuals. by Otto Tschritter (36354)

“…Blood glucose was measured twice at baseline and every 5–10 minutes during the infusion of human insulin, insulin detemir or saline. …”

Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate by Sophia T. Mundle (303078)

“…There are estimates that this enzyme is responsible for eliminating as many as 10⁵ potentially mutagenic and genotoxic lesions from the genome of each cell every day. …”